Transient acidosis induces delayed neurotoxicity in cultured hippocampal slices

A simple method for organotypic cultures of nervous tissue

1991 • 3,075 citations

Cerebral hypoxia: some new approaches and unanswered questions

1990 • 674 citations

Synaptic Activity Mediates Death of Hypoxic Neurons

1983 • 441 citations

Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures

1990 • 372 citations

N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture.

1987 • 309 citations

Mechanisms involved in irreversible anoxic damage to the in vitro rat hippocampal slice

1982 • 261 citations

Organotypic cultures of neural tissue

1988 • 250 citations

Acid-induced death in neurons and glia

1991 • 241 citations

Hydrogen Ions Kill Brain at Concentrations Reached in Ischemia

1987 • 237 citations

Dynamics of interstitial and intracellular pH in evolving brain infarct

1991 • 211 citations

Neuroprotective Effects of Glutamate Antagonists and Extracellular Acidity

1993 • 202 citations

Mild acidosis protects hippocampal neurons from injury induced by oxygen and glucose deprivation

1990 • 202 citations

Enhancement of Iron-Catalyzed Free Radical Formation by Acidosis in Brain Homogenates: Difference in Effect by Lactic Acid and CO₂

1989 • 201 citations

Evolving Concepts About the Role of Acidosis in Ischemic Neuropathology

1993 • 191 citations

Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures

1991 • 175 citations

The Effects of Extracellular Acidosis on Neurons and Glia in vitro

1989 • 154 citations

Ketamine protects cultured neocortical neurons from hypoxic injury

1986 • 144 citations

Acidosis-related brain damage.

1993 • 143 citations

Increased glucose improves recovery of neuronal function after cerebral hypoxia in vitro

1987 • 104 citations

Extracellular pH in the Brain during Ischemia: Relationship to the Severity of Lactic Acidosis

1991 • 77 citations

Phencyclidine receptor ligands attenuate cortical neuronal injury after N-methyl-D-aspartate exposure or hypoxia.

1988 • 76 citations

Mechanistic Distinctions between Excitotoxic and Acidotic Hippocampal Damage in an in vitro Model of Ischemia

1990 • 74 citations

Acidosis-Induced Ischemic Brain Damage: Are Free Radicals Involved?

1991 • 55 citations

Brain pHi, cerebral blood flow, and NADH fluorescence during severe incomplete global ischemia in rabbits.

1993 • 38 citations

Intracellular pH in rat brain in vivo and in brain slices

1992 • 37 citations

Acute Brain Injury, NMDA Receptors, and Hydrogen Ions: Observations in Cortical Cell Cultures

1990 • 34 citations

5-(N-ethyl-N-isopropyl)amiloride and mild acidosis protect cultured cerebellar granule cells against glutamate-induced delayed neuronal death

1992 • 32 citations

Excitatory and inhibitory pathways modulate kainate excitotoxicity in hippocampal slice cultures

1993 • 25 citations

Mild acidosis inhibits the rise in intracellular Ca2+ concentration in response to oxygen-glucose deprivation in rat hippocampal slices

1994 • 22 citations

Pregnancy Increases Reactivity of Mice to Phenobarbital

1983 • 9 citations