The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication

Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea

1989 • 2,019 citations

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

1980 • 854 citations

Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques.

1991 • 705 citations

Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines.

1990 • 697 citations

Elimination of Metabolic Cooperation in Chinese Hamster Cells by a Tumor Promoter

1979 • 559 citations

Skin Tumor-Promoting Activity of Benzoyl Peroxide, a Widely Used Free Radical-Generating Compound

1981 • 510 citations

Growth inhibition of transformed cells correlates with their junctional communication with normal cells

1986 • 416 citations

Regulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherin.

1991 • 366 citations

Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis

1981 • 228 citations

Carcinogenicity of epoxides, lactones, and peroxy compounds. II.

1965 • 211 citations

The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins.

1991 • 162 citations

The presence of alpha 2u-globulin is necessary for d-limonene promotion of male rat kidney tumors.

1991 • 157 citations

Tumor-promoting activity of phorbol and four diesters of phorbol in mouse skin.

1971 • 155 citations

Properties of hypolipidemic peroxisome proliferators in the lymphocyte [3H]thymidine and Salmonella mutagenesis assays.

1980 • 148 citations

Two-Year Carcinogenicity Study of Sodium Fluoride in Rats

1990 • 146 citations

The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil

1989 • 145 citations

Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-α-p-chlorophenoxyisobutyrate (clofibrate) in rats

1979 • 143 citations

Connexin43 in MDCK cells: regulation by a tumor-promoting phorbol ester and Ca2+.

1992 • 141 citations

Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis

1986 • 136 citations

Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity

1989 • 134 citations

Inhibition of cell-cell communication by tumor promoters.

1982 • 119 citations

CLASSIFICATION OF GENOTOXIC AND EPIGENETIC HEPATOCARCINOGENS USING LIVER CULTURE ASSAYS*

1980 • 105 citations

Selective lack of intercellular communication between transformed and nontransformed cells as a common property of chemical and oncogene transformation of BALB/c 3T3 cells.

1987 • 103 citations

Lack of intercellular communication between chemically transformed and surrounding nontransformed BALB/c 3T3 cells.

1984 • 100 citations

Inhibition of intercellular communication between liver cells by the liver tumor promoter 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane

1981 • 99 citations

Effect of phorbol myristate acetate on the recovery of spontaneous and ultraviolet light-induced 6-thioguanine and ouabain-resistant Chinese hamster cells.

1977 • 97 citations

The predictive value of mouse liver tumour induction in carcinogenicity testing—a literature survey

1973 • 95 citations

The human relevance of the renal tumor-inducing potential of d-limonene in male rats: Implications for risk assessment

1991 • 89 citations

Gap-junctional intercellular communication in epidermal cell lines from selected stages of SENCAR mouse skin carcinogenesis.

1989 • 78 citations

Further evidence for the involvement of gap-junctional intercellular communication in induction and maintenance of transformed foci in BALB/c 3T3 cells.

1988 • 77 citations

Inhibition of gap junctional intercellular communication in Syrian hamster embryo cells by TPA, retinoic acid and DDT

1994 • 68 citations

Cytotoxic, mutagenic, and cell-cell communication inhibitory properties of DDT, lindane, and chlordane on Chinese hamster cellsin vitro

1983 • 67 citations

Lack of cytogenetic effects in mice or mutations in Salmonella receiving sodium fluoride

1979 • 66 citations

Colocalized alterations in connexin32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters.

1994 • 65 citations

Rapid and reversible inhibition of junctional communication by tumor promoters in a mouse cell line.

1983 • 61 citations

The effects of long-term feeding of DDT to BALB/c mice

1973 • 58 citations

Collaborative study of mutagenicity with Salmonella typhimurium TA102

1992 • 57 citations

Inhibition of mouse hepatocyte intercellular communication by paraquat-generated oxygen free radicals

1988 • 57 citations

Characterizations of and interactions between bile ductule cells and hepatocytes in early stages of rat hepatocarcinogenesis induced by ethionine.

1991 • 54 citations

Two inhibitors of gap junctional intercellular communication, TPA and endosulfan: Different effects on phosphorylation of connexin 43 in the rat liver epithelial cell line, IAR 20

1994 • 53 citations

Inhibition of intercellular communication between mouse hepatocytes by tumor promoters*1, *2

1987 • 51 citations

Inhibition of metabolic cooperation in Chinese hamster cells by various chemical including tumor promoters.

1980 • 50 citations

Variation in drug-metabolizing enzyme activities during the growth of human Hep G2 hepatoma cells

1990 • 49 citations

Selective gap-junctional communication capacity of transformed and non-transformed rat liver epithelial cell lines

1988 • 48 citations

Antioxidant prevention of tumor promoter induced inhibition of mouse hepatocyte intercellular communication

1986 • 47 citations

Inhibition of junctional intercellular communication as a possible short-term test to detect tumor-promoting agents: results with nine chemicals tested by dye transfer assay in Chinese hamster V79 cells.

1986 • 45 citations

Non-mutagenicity for salmonella of the chlorinated hydrocarbons aroclor 1254, 1,2,4-trichlorobenzene, mirex and kepone

1979 • 45 citations

Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity

1989 • 42 citations

The in vitro metabolism, macromolecular binding and bacterial mutagenicity of 4-chloribiphenyl, a model PCB substrate.

1976 • 40 citations

Mutagenicity testing of chlorinated biphenyls and chlorinated dibenzofurans

1982 • 39 citations

Effects of various concentrations of ethyl-α-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat

1982 • 39 citations

Characterization of gap junctional communication-deficient mutants of a rat liver epithelial cell line.

1993 • 38 citations

Alteration of calcium transport by tumor promoters, 12-O-tetradecanoyl phorbol-13-acetate and p,p′-dichlorodiphenyltrichloroethane, in the Chinese hamster V79 fibroblast cell line

1983 • 38 citations

Comparison of some carcinogenic, mutagenic, and biochemical properties of S-vinylhomocysteine and ethionine.

1982 • 36 citations

Assessment of the subchronic oral toxicity of d-limonene in dogs

1990 • 34 citations

Intercellular communication capacity as a possible determinant of transformation sensitivity of BALB/c 3T3 clonal cells.

1985 • 34 citations

Possible Molecular Mechanism of Loss of Homologous and Heterologous Gap Junctional Intercellular Communication in Rat Liver Epithelial Cell Lines

1994 • 33 citations

Effect of retinol and cigarette-smoke condensate on dye-coupled intercellular communication between hamster tracheal epithelial cells

1988 • 30 citations

Sex differential and dose dependence of phenobarbital-promoting activity in N-bis(2-hydroxypropyl)nitrosamine-initiated thyroid tumorigenesis in rats.

1985 • 29 citations

Effect of tumor promoting stimuli on gap junction permeability and connexin 43 expression in ARL 18 rat liver cell line

1993 • 28 citations

Enhanced mutagenicity of anisidine isomers in bacterial strains containing elevated N-acetyltransferase activity

1992 • 28 citations

An improved long-term culture of rat hepatocytes to detect liver tumour-promoting agents: results with phenobarbital

1993 • 27 citations

Carcinogenicity testing of some constituents of black pepper

1992 • 21 citations

Use of a new citrulline incorporation assay to investigate inhibition of intercellular communication by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane in human fibroblasts.

1985 • 21 citations

Role of cyclic AMP in the inhibition of mouse hepatocyte intercellular communication by liver tumor promoters

1987 • 20 citations

Modulation of oxidant formation in mouse skin in vivo by tumor-promoting phorbol esters.

1994 • 20 citations

Evidence for a common genetic pathway controlling susceptibility to mouse skin tumor promotion by diverse classes of promoting agents.

1991 • 18 citations

Identification of tumor promoters by their inhibitory effect on intercellular transfer of lucifer yellow

1989 • 18 citations

Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells.

1992 • 15 citations

Synergism of Environmental Carcinogens and Promoters on Bladder Cancer Development Initiated by N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine in F344 Rats

1992 • 14 citations

Inhibitory effects of the phorboloester TPA and cigarette smoke condensate on the mutagenicity of benzo[a]pyrene in a co-cultivation system

1986 • 12 citations

Effect of simultaneous administration of clofibrate with diethylnitrosamine on hepatic tumorigenesis in the rat

1983 • 10 citations

12-O-Tetradecanoylphorbol-13-acetate-mediated systemic co-promotion in the murine skin multistage carcinogenesis protocol

1993 • 5 citations

Deficiency of tyrosine phosphorylation in a Balb/c 3T3 cell variant hypersensitive to phorbol ester-induced cell transformation

1994 • 3 citations

Cell-to-cell communication in cultured rat thyroid monolayer cells is inhibited dose-dependently by methimazole.

1992 • 3 citations