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Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis

Data up to Jan 2025

Published1986
Citations136
References21

Total Citations Per Year

Abstract

References (21)

Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.

1975 • 504 citations

Indole alkaloids: dihydroteleocidin B, teleocidin, and lyngbyatoxin A as members of a new class of tumor promoters.

1981 • 254 citations

New Classes of Tumor Promoters: Teleocidin, Aplysiatoxin, and Palytoxin

1987 • 205 citations

A possible naturally occurring tumor promoter, teleocidin B from Streptomyces

1979 • 130 citations

The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

1985 • 107 citations

Natural products and drug development

1984 • 96 citations

Direct measurment of specific binding of highly lipophilic phorbol diester to mouse epidermal membranes using cold acetone

1981 • 81 citations

Stimulation of prostaglandin E2 production by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters in macrophages and its inhibition by cycloheximide

1985 • 78 citations

Increase in histidine decarboxylase activity in mouse skin after application of the tumor promoter tetradecanoylphorbol acetate

1981 • 75 citations

Teleocidin from Streptomyces is a potent promoter of mouse skin carcinogenesis

1982 • 74 citations

Thapsigargin and thapsigargicin, two histamine liberating sesquiterpene lactones from Thapsia garganica. X-ray analysis of the 7,11-epoxide of thapsigargin

1982 • 69 citations

Estimation of tumor promoting activity and structure-function relationships of aplysiatoxins

1984 • 56 citations

Absolute configurations of the histamine liberating sesquiterpene lactones thapsigargin and trilobolide

1985 • 49 citations

New classes of environmental tumor promoters: indole alkaloids and polyacetates.

1983 • 49 citations

Thapsia garganicaからの,ヒスタミン放出性の二種のセスキテルペンラクトン,タプシガルジン及びタプシガルジシン タプシガルジンの7,11-エポキシドのX線解析 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター

1982 • 48 citations

Specific binding of the tumor promoter TPA in various mouse organs as measured by a 'cold acetone-filter assay'

1981 • 39 citations

Structure of histamine releasing guaianolides from Thapsia species

1984 • 32 citations

Palytoxin both Induces and Inhibits the Release of Histamine from Rat Mast Cells

1982 • 30 citations

Inhibition of histidine decarboxylase and tumour promoter-induced arachidonic acid release by lecanoric acid analogues

1983 • 14 citations

Induction of histidine decarboxylase activity in mouse skin after application of indole alkaloids, a new class of tumor promoter

1982 • 11 citations

Studies on olivoretins indicate a requirement for a free hydroxyl group for teleocidin B activity.

1984 • 10 citations

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Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate… (1986) – Journal of Cancer Research and Clinical Oncology | Metascience Observatory Explorer