Characterizations of and interactions between bile ductule cells and hepatocytes in early stages of rat hepatocarcinogenesis induced by ethionine.

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

1966 • 6,585 citations

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

1974 • 3,882 citations

Histochemistry of Hepatic Phosphatases at a Physiologic pH: With Special Reference to the Demonstration of Bile Canaliculi

1957 • 1,831 citations

Rat liver peroxisomes catalyze the beta oxidation of fatty acids.

1978 • 608 citations

The multistep nature of cancer development.

1984 • 510 citations

A precursor—product relationship exists between oval cells and hepatocytes in rat liver

1987 • 448 citations

A diploid epithelial cell line from normal adult rat liver with phenotypic properties of ?oval? cells*1

1984 • 381 citations

In vivo differentiation of rat liver oval cells into hepatocytes.

1989 • 318 citations

Evidence for the stem cell origin of hepatocellular carcinoma and cholangiocarcinoma.

1989 • 294 citations

PEROXISOMES IN ABSORPTIVE CELLS OF MAMMALIAN SMALL INTESTINE

1972 • 262 citations

Early histological and functional alterations of ethionine liver carcinogenesis in rats fed a choline-deficient diet.

1978 • 248 citations

STUDIES ON MICROPEROXISOMES II. A CYTOCHEMICAL METHOD FOR LIGHT AND ELECTRON MICROSCOPY

1972 • 231 citations

Regression and persistence of hyperplastic hepatic nodules induced by N-2-Fluorenylacetamide and their relationship to hepatocarcinogenesis.

1971 • 221 citations

STUDIES ON MICROPEROXISOMES V. ARE MICROPEROXISOMES UBIQUITOUS IN MAMMALIAN CELLS?

1973 • 177 citations

Promotion of growth and differentiation of rat ductular oval cells in primary culture.

1988 • 142 citations

Isolation, Culture, and Transplantation of Intrahepatic Biliary Epithelial Cells and Oval Cells

1990 • 141 citations

Origin and fate of proliferated hepatic ductal cells in the rat: Electron microscopic and autoradiographic studies

1964 • 128 citations

GLUTATHIONE S‐TRANSFERASES AND HEPATOCARCINOGENESIS

1988 • 123 citations

Growth in culture and tumorigenicity after transfection with the ras oncogene of liver epithelial cells from carcinogen-treated rats.

1987 • 116 citations

Different lineages of chemically induced hepatocellular carcinoma in rats defined by monoclonal antibodies.

1989 • 111 citations

Isolation of oval cells by centrifugal elutriation and comparison with other cell types purified from normal and preneoplastic livers.

1984 • 110 citations

Isozyme profiles of oval cells, parenchymal cells, and biliary cells isolated by centrifugal elutriation from normal and preneoplastic livers.

1984 • 94 citations

Cellular and molecular changes in the early stages of chemical hepatocarcinogenesis in the rat.

1990 • 93 citations

In situ hybridization studies on expression of albumin and alpha-fetoprotein during the early stage of neoplastic transformation in rat liver.

1987 • 93 citations

Antigenic relationship between oval cells and a subpopulation of hepatic foci, nodules, and carcinomas induced by the "resistant hepatocyte" model system.

1991 • 83 citations

An Antigenic Portrait of the Liver during Carcinogenesis

1990 • 83 citations

Monoclonal antibodies recognizing oval cells induced in the liver of rats by N-2-fluorenylacetamide or ethionine in a choline-deficient diet.

1985 • 81 citations

STUDIES ON MICROPEROXISOMES III. OBSERVATIONS ON HUMAN AND RAT HEPATOCYTES

1973 • 80 citations

Effects of choline deficiency on rat hepatocytes.

1971 • 71 citations

Purification and characterization of P-52 (glutathione S-transferase-P or 7-7) from normal liver and putative preneoplastic liver nodules.

1988 • 45 citations

Expression of hepatocyte and oval cell antigens in hepatocellular carcinomas produced by oncogene-transfected liver epithelial cells.

1990 • 42 citations

A characteristic electrophoretic pattern of cytosolic polypeptides from hepatocyte nodules generated during liver carcinogenesis in several models

1983 • 38 citations

Immunocytochemical localization of lysosomal beta-galactosidase in rat liver.

1983 • 25 citations

Immunocytochemical localization of epoxide hydrase in hyperplastic nodules induced in rat liver by 2-acetylaminofluorene.

1979 • 24 citations

A structural analysis of gap and tight junctions in the rat liver during a dietary treatment that induces oval cell proliferation.

1986 • 13 citations