Regulation of the peptidylglutamyl-peptide hydrolyzing activity of the pituitary multicatalytic proteinase complex

Purification of two high molecular weight proteases from rabbit reticulocyte lysate.

1987 • 542 citations

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

1990 • 464 citations

Ubiquitin-Mediated Pathways for Intracellular Proteolysis

1987 • 409 citations

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

1988 • 404 citations

ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin.

1989 • 370 citations

Evidence that Pituitary Cation‐Sensitive Neutral Endopeptidase Is a Multicatalytic Protease Complex

1983 • 356 citations

The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins.

1990 • 327 citations

Cation‐Sensitive Neutral Endopeptidase: Isolation and Specificity of the Bovine Pituitary Enzyme

1980 • 313 citations

The multicatalytic proteinase of mammalian cells

1989 • 242 citations

Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor

1985 • 231 citations

Proteasomes (multi-protease complexes) as 20 S ring-shaped particles in a variety of eukaryotic cells.

1988 • 225 citations

Activation of the multicatalytic proteinase from rat skeletal muscle by fatty acids or sodium dodecyl sulphate

1985 • 184 citations

The Role of Negative Cooperativity and Half-of-the-Sites Reactivity in Enzyme Regulation

1976 • 158 citations

Pituitary multicatalytic proteinase complex. Specificity of components and aspects of proteolytic activity

1989 • 139 citations

A multicatalytical protease complex from pituitary that forms enkephalin and enkephalin containing peptides

1981 • 122 citations

The high molecular weight multicatalytic proteinase, macropain, exists in a latent form in human erythrocytes

1989 • 115 citations

Kinetic studies of the differential effect of detergents on the peptidase activities of the multicatalytic proteinase from rat liver.

1990 • 89 citations

Size and shape of the multicatalytic proteinase from rat skeletal muscle

1986 • 73 citations

Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome)

1990 • 67 citations

Purification and characterization of a multicatalytic proteinase from crustacean muscle: Comparison of latent and heat-activated forms

1989 • 58 citations

N‐Terminal sequence similarities between components of the multicatalytic proteinase complex

1990 • 56 citations

Identification and partial purification of a cation-sensitive neutral endopeptidase from bovine pituitaries

1979 • 42 citations

Comparative studies on lens neutral endopeptidase and pituitary neutral proteinase: two closely similar enzymes

1986 • 25 citations

Multicatalytic proteinase complex or multicatalytic proteinase: a high-Mr endopeptidase

1988 • 22 citations