Exon skipping without splice site mutation accounting for abnormal immunoglobulin chains in nonsecretory human myeloma

In vitro methods in cell-mediated and tumor immunity

1976 • 1,266 citations

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1981 • 959 citations

ALTERNATIVE SPLICING IN THE CONTROL OF GENE EXPRESSION

1989 • 701 citations

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

1980 • 402 citations

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein.

1987 • 343 citations

Organization of human immunoglobulin heavy chain diversity gene loci.

1988 • 317 citations

Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region.

1980 • 199 citations

The nucleotide sequence of a human immnnoglobulin C_γlgene

1982 • 158 citations

Structure of a monoclonal kappa chain of the V kappa IV subgroup in the kidney and plasma cells in light chain deposition disease.

1991 • 95 citations

Structurally abnormal immunoglobulins in human immunoproliferative disorders

1992 • 81 citations

Intracellular “Monoclonal” Immunoglobulin in Non-secretory Human Myeloma

1970 • 72 citations

Intracytoplasmic and surface-bound immunoglobulins in "nonsecretory" and Bence-Jones myeloma.

1976 • 72 citations

Structurally abnormal immunoglobulins in human immunoproliferative disorders

1992 • 71 citations

Synthesis of abnormal heavy and light chains in multiple myeloma with visceral deposition of monoclonal immunoglobulin.

1980 • 67 citations

Gamma heavy chain disease in man. Genomic sequence reveals two noncontiguous deletions in a single gene.

1988 • 41 citations

Multiple genomic defects result in an alternative RNA splice creating a human gamma H chain disease protein.

1988 • 33 citations

Immunoglobulin VH determinants defined by monoclonal antibodies.

1982 • 31 citations

Structure and expression of human germline VH transcripts.

1991 • 31 citations

Derivation and Diversification of Monoclonal Antibodies

1986 • 25 citations

Correct in vivo splicing of the mouse immunoglobulin kappa light-chain pre-mRNA is dependent on 5' splice-site position even in the absence of transcription.

1988 • 23 citations

Accurate 5' splice-site selection in mouse kappa immunoglobulin light chain premessenger RNAs is not cell-type-specific.

1987 • 22 citations

Alternate splice sites within the human VH gene coding sequences lead to truncated Ig mu-chains.

1990 • 13 citations

Co-expression of full-length and truncated Ig mu-chains in human B lymphocytes results from alternative splicing of a single primary RNA transcript.

1991 • 13 citations

In vitro splicing of kappa immunoglobulin precursor mRNA.

1987 • 13 citations

Synthesis of abnormal heavy chains in Bence-Jones plasma cell leukemia with intracellular IgG

1980 • 12 citations