The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

1983 • 14,615 citations

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

THIOREDOXIN

1985 • 1,885 citations

Solvation energy in protein folding and binding

1986 • 1,853 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

Rapid recording of 2D NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins

1989 • 1,395 citations

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

1992 • 1,012 citations

Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonance

1983 • 1,012 citations

Quantitative J correlation: a new approach for measuring homonuclear three-bond J(HNH.alpha.) coupling constants in 15N-enriched proteins

1993 • 975 citations

Enzymatic Synthesis of Deoxyribonucleotides

1964 • 917 citations

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

1993 • 891 citations

Overcoming the overlap problem in the assignment of proton NMR spectra of larger proteins by use of three-dimensional heteronuclear proton-nitrogen-15 Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1.beta.

1989 • 840 citations

Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62

1992 • 825 citations

Protein Hydration in Aqueous Solution

1991 • 778 citations

Determination of three‐dimensional structures of proteins from interproton distance data by hybrid distance geometry‐dynamical simulated annealing calculations

1988 • 775 citations

Methodological Advances in Protein NMR

1993 • 721 citations

Amino acid type determination in the sequential assignment procedure of uniformly 13C/15N-enriched proteins

1993 • 692 citations

Methodological advances in protein NMR

1993 • 686 citations

A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams

1991 • 682 citations

Solution conformation of proteinase inhibitor IIA from bull seminal plasma by 1H nuclear magnetic resonance and distance geometry

1985 • 610 citations

Correlation of Backbone Amide and Aliphatic Side-Chain Resonances in 13C/15N-Enriched Proteins by Isotropic Mixing of 13C Magnetization

1993 • 591 citations

Three-dimensional heteronuclear NMR of nitrogen-15 labeled proteins

1989 • 584 citations

1H1H correlation via isotropic mixing of 13C magnetization, a new three-dimensional approach for assigning 1H and 13C spectra of 13C-enriched proteins

1990 • 580 citations

Protein structures in solution by nuclear magnetic resonance and distance geometry

1987 • 569 citations

Crystal structure of thioredoxin from Escherichia coli at 1.68 Å resolution

1990 • 568 citations

Determination of three‐dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms Circumventing problems associated with folding

1988 • 546 citations

Determination of three-dimensional structures of proteins by simulated annealing with interproton distance restraints. Application to crambin, potato carboxypeptidase inhibitor and barley serine proteinase inhibitor 2

1988 • 537 citations

Comparison of different modes of two-dimensional reverse-correlation NMR for the study of proteins

1990 • 510 citations

Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin

1993 • 490 citations

Three-dimensional structure of interleukin 8 in solution

1990 • 441 citations

Structures of Larger Proteins in Solution: Three- and Four-Dimensional Heteronuclear NMR Spectroscopy

1991 • 437 citations

Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution.

1975 • 435 citations

Regulation of CO2 assimilation in oxygenic photosynthesis: The ferredoxin/thioredoxin system

1991 • 393 citations

An efficient experiment for sequential backbone assignment of medium-sized isotopically enriched proteins

1992 • 391 citations

Differential reactivity of the functional sulfhydryl groups of cysteine-32 and cysteine-35 present in the reduced form of thioredoxin from Escherichia coli.

1980 • 364 citations

Structural and functional relations among thioredoxins of different species

1991 • 363 citations

Three-dimensional structure of proteins determined by molecular dynamics with interproton distance restraints: application to crambin.

1986 • 322 citations

Four-Dimensional Heteronuclear Triple-Resonance NMR Spectroscopy of Interleukin-1β in Solution

1990 • 308 citations

Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2.

1990 • 283 citations

An alternative 3D NMR technique for correlating backbone 15N with side chain Hβ resonances in larger proteins

1991 • 273 citations

Optimized recording of heteronuclear multidimensional NMR spectra using pulsed field gradients

1992 • 264 citations

Mimicking the active site of protein disulfide-isomerase by substitution of proline 34 in Escherichia coli thioredoxin

1991 • 256 citations

Application of molecular dynamics with interproton distance restraints to three-dimensional protein structure determination

1986 • 252 citations

Comparison of techniques for 1H-detected heteronuclear 1H15N Spectroscopy

1990 • 251 citations

The three-dimensional structure of α1-purothionin in solution: combined use of nuclear magnetic resonance, distance geometry and restrained molecular dynamics

1986 • 250 citations

Three-dimensional structure of potato carboxypeptidase inhibitor in solution. A study using nuclear magnetic resonance, distance geometry, and restrained molecular dynamics

1987 • 235 citations

The role of thioredoxin in filamentous phage assembly. Construction, isolation, and characterization of mutant thioredoxins.

1986 • 223 citations

High-Resolution Solution Structure of the β Chemokine hMIP-1β by Multidimensional NMR

1994 • 214 citations

Sampling and efficiency of metric matrix distance geometry: A novel partial metrization algorithm

1992 • 204 citations

Practical aspects of proton-carbon-carbon-proton three-dimensional correlation spectroscopy of 13C-labeled proteins

1990 • 200 citations

Increased Resolution and Improved Spectral Quality in Four-Dimensional 13C/13C-Separated HMQC-NOESY-HMQC Spectra Using Pulsed Field Gradients

1993 • 187 citations

Tryptophan Fluorescence Study of Conformational Transitions of the Oxidized and Reduced Form of Thioredoxin

1972 • 164 citations

Four-dimensional carbon-13/carbon-13-edited nuclear Overhauser enhancement spectroscopy of a protein in solution: application to interleukin 1.beta.

1991 • 162 citations

Three-dimensional solution structure of the reduced form of Escherichia coli thioredoxin determined by nuclear magnetic resonance spectroscopy

1990 • 160 citations

Exploring the Limits of Precision and Accuracy of Protein Structures Determined by Nuclear Magnetic Resonance Spectroscopy

1993 • 155 citations

Assessing the Quality of Solution Nuclear Magnetic Resonance Structures by Complete Cross-Validation

1993 • 150 citations

Interaction of mutant thioredoxins of Escherichia coli with the gene 5 protein of phage T7. The redox capacity of thioredoxin is not required for stimulation of DNA polymerase activity.

1986 • 146 citations

Measurement of amide proton exchange rates and NOEs with water in 13C/15N-enriched calcineurin B

1993 • 144 citations

Measurement of three-bond nitrogen-carbon J couplings in proteins uniformly enriched in nitrogen-15 and carbon-13

1993 • 144 citations

Triple-resonance multidimensional NMR study of calmodulin complexed with the binding domain of skeletal muscle myosin light-chain kinase: indication of a conformational change in the central helix

1991 • 143 citations

High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution

1991 • 141 citations

The Impact of Direct Refinement against Three-Bond HN-CαH Coupling Constants on Protein Structure Determination by NMR

1994 • 136 citations

The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy

1993 • 124 citations

Comparison of backbone and tryptophan side-chain dynamics of reduced and oxidized Escherichia coli thioredoxin using nitrogen-15 NMR relaxation measurements

1993 • 119 citations

Measurement of long-range 13C-13C J couplings in a 20-kDa protein-peptide complex

1992 • 114 citations

Relationship between electrostatics and redox function in human thioredoxin: characterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR

1992 • 109 citations

A simple and sensitive experiment for measurement of JCC couplings between backbone carbonyl and methyl carbons in isotopically enriched proteins

1993 • 106 citations

Stereospecific assignment of β-methylene protons in larger proteins using 3D15N-separated Hartmann-Hahn and13C-separated rotating frame Overhauser spectroscopy

1991 • 105 citations

Substitution of the conserved tryptophan 31 in Escherichia coli thioredoxin by site-directed mutagenesis and structure-function analysis

1991 • 101 citations

¹H‐Nmr stereospecific assignments by conformational data‐base searches

1990 • 100 citations

Isolation and Characterization of Calf Liver Thioredoxin

1974 • 100 citations

A 3D triple-resonance NMR technique for qualitative measurement of carbonyl-Hβ J couplings in isotopically enriched proteins

1992 • 77 citations

Characterization of Escherichia coli thioredoxins with altered active site residues

1990 • 55 citations

Localization of bound water in the solution structure of a complex of the erythroid transcription factor GATA-1 with DNA

1994 • 49 citations

Determination of the positions of bound water molecules in the solution structure of reduced human thioredoxin by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy

1991 • 44 citations

A mutant thioredoxin from Escherichia coli tsnC 7007 that is nonfunctional as subunit of phage T7 DNA polymerase.

1981 • 42 citations

Assignment of the ¹⁵N NMR spectra of reduced and oxidized Escherichia coli thioredoxin

1991 • 41 citations

Structural differences between oxidized and reduced thioredoxin monitored by two‐dimensional ¹H NMR spectroscopy

1988 • 38 citations

Effect of disulfide bridge formation on the NMR spectrum of a protein: Studies on oxidized and reduced Escherichia coli thioredoxin

1994 • 32 citations

High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.

1991 • 31 citations

1H and15N resonance assignments and secondary structure of the human thioredoxin C62A, C69A, C73A mutant

1992 • 25 citations

Reduction of thioredoxin significantly decreases its partial specific volume and adiabatic compressibility

1992 • 25 citations

Differences in hydrogen exchange behavior between the oxidized and reduced forms of Escherichia coli thioredoxin

1992 • 17 citations