A mouse model of human L1 retrotransposition

Initial sequencing and analysis of the human genome

2001 • 23,520 citations

Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition

1993 • 1,129 citations

Human L1 Retrotransposon Encodes a Conserved Endonuclease Required for Retrotransposition

1996 • 1,093 citations

High Frequency Retrotransposition in Cultured Mammalian Cells

1996 • 989 citations

Biology of Mammalian L1 Retrotransposons

2001 • 751 citations

Reverse Transcriptase Encoded by a Human Transposable Element

1991 • 748 citations

Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons

1997 • 546 citations

Separation of mouse spermatogenic cells by sedimentation velocity

1976 • 505 citations

Many human L1 elements are capable of retrotransposition

1997 • 436 citations

Identification, characterization, and cell specificity of a human LINE-1 promoter.

1990 • 419 citations

Positional cloning of the gene for X-linked retinitis pigmentosa 2

1998 • 371 citations

Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA.

1996 • 338 citations

The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposons.

1986 • 326 citations

Transcriptional and translational regulation of gene expression in haploid spermatids

1999 • 294 citations

L1 (LINE-1) Retrotransposon Evolution and Amplification in Recent Human History

2000 • 290 citations

Determination of L1 retrotransposition kinetics in cultured cells

2000 • 272 citations

Twin Priming: A Proposed Mechanism for the Creation of Inversions in L1 Retrotransposition

2001 • 238 citations

Developmental and cell type specificity of LINE-1 expression in mouse testis: implications for transposition.

1994 • 238 citations

Targeting of Human Retrotransposon Integration Is Directed by the Specificity of the L1 Endonuclease for Regions of Unusual DNA Structure

1998 • 236 citations

Taming of transposable elements by homology-dependent gene silencing

1999 • 221 citations

Real‐time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein

1999 • 191 citations

An actively retrotransposing, novel subfamily of mouse L1 elements

1998 • 187 citations

Full-Length Human L1 Insertions Retain the Capacity for High Frequency Retrotransposition in Cultured Cells

1999 • 158 citations

In vitro properties of the first ORF protein from mouse LINE-1 support its role in ribonucleoprotein particle formation during retrotransposition

1997 • 158 citations

Tightly regulated, developmentally specific expression of the first open reading frame from LINE-1 during mouse embryogenesis.

1995 • 150 citations

Expression of a Glyceraldehyde 3-Phosphate Dehydrogenase Gene Specific to Mouse Spermatogenic Cells1

1992 • 147 citations

The LINE-1 DNA sequences in four mammalian orders predict proteins that conserve homologies to retrovirus proteins

1987 • 132 citations

Frequency of recent retrotransposition events in the human factor IX gene

2001 • 88 citations

The F-type 5′ motif of mouse L1 elements: a major class of L1 termini similar to the A-type in organization but unrelated in sequence

1988 • 68 citations