Frequent deletions in nine newly immortal human cell lines

A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMES

1971 • 5,049 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

Allelotype of Colorectal Carcinomas

1989 • 1,333 citations

Hereditary cancer, oncogenes, and antioncogenes.

1985 • 1,261 citations

Chromosome Abnormalities and Genetic Counseling

2011 • 852 citations

Chromosomal Imbalance in the Aniridia-Wilms' Tumor Association: 11p Interstitial Deletion

1978 • 726 citations

Replicative Senescence: the Human Fibroblast Comes of Age

1990 • 649 citations

Tumor Suppressor Genes: The Puzzle and the Promise

1989 • 488 citations

Tumorigenicity in Human Melanoma Cell Lines Controlled by Introduction of Human Chromosome 6

1990 • 333 citations

Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization.

1990 • 256 citations

Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen

1989 • 252 citations

Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21.

1991 • 207 citations

The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses

1990 • 200 citations

Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas.

1990 • 189 citations

SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts

1990 • 183 citations

Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.

1991 • 179 citations

Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens

1982 • 174 citations

Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells

1991 • 156 citations

Mutation and the environment

1990 • 148 citations

Towards an understanding of the malignant transformation of diploid human fibroblasts

1988 • 121 citations

Immortalization of Human Fibroblasts Transformed by Origin-Defective Simian Virus 40

1987 • 105 citations

Detection of mycoplasma in cell cultures

1967 • 68 citations

Immortalization of human fibroblasts transformed by origin-defective simian virus 40.

1987 • 65 citations

Spontaneous Immortalization Rate of Cultured Chinese Hamster Cells2

1986 • 57 citations

A new multi-locus DNA fingerprinting probe: pV47-2

1990 • 50 citations

Chromosome abnormalities and genetic counseling.

1990 • 43 citations

Human fibroblasts transformed by the early region of SV40 DNA: Analysis of “free” viral DNA sequences

1980 • 40 citations

Spontaneous in vitro neoplastic evolution: Recurrent chromosome changes of newly immortalized Chinese hamster cells

1986 • 30 citations

SV40-transformed human fibroblasts exhibit a characteristic chromosomal pattern

1988 • 27 citations

Karyotype evolution of the simian virus 40-transformed human cell line LNSV

1979 • 19 citations

c-myb gene analysis in T-cell malignancies with del(6q)

1990 • 19 citations

Efficient Immortalization by SV40 T DNA of Skin Fibroblasts From Patients With Wilms' Tumor Associated With Chromosome 11p Deletion

1989 • 18 citations

Karyotype evolution in a simian virus 40-transformed tumorigenic human cell line

1990 • 14 citations

Rapid isoenzyme analysis of cell cultures by agarose electrophoresis II. Intraspecies identification of human cell lines

1983 • 11 citations

Immortalization as an endpoint in studies on malignant transformation.

1990 • 4 citations