Immortalization of Human Fibroblasts Transformed by Origin-Defective Simian Virus 40

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Establishment of a line of human fetal glial cells that supports JC virus multiplication.

1985 • 318 citations

Limited and unlimited growth of sv40-transformed cells from human diploid mrc-5 fibroblasts

1983 • 241 citations

Expression of early genes of origin-defective mutants of simian virus 40.

1980 • 205 citations

Origin-defective Mutants of SV40

1980 • 193 citations

Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen

1984 • 163 citations

In vitro transformation of human epithelial cells

1986 • 148 citations

Human cell transformation by simian virus 40—A review

1981 • 135 citations

Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells.

1982 • 130 citations

Enhanced transformation of human fibroblasts by origin-defective simian virus 40

1982 • 123 citations

Immortalization of rodent embryo fibroblasts by SV40 Is maintained by the Å gene

1983 • 100 citations

SV40 T antigen induction and transformation in human fibroblast cell strains

1968 • 88 citations

A fragment of the SV40 large T-antigen gene transforms

1982 • 86 citations

Establishment and characterization of a permanent pSV ori−-transformed ataxia-telangiectasia cell line

1985 • 86 citations

Efficient transformation of human fibroblasts by adenovirus-simian virus 40 recombinants.

1984 • 80 citations

The biology of human cells in tissue culture. I. Characterization of cells derived from osteogenic sarcomas

1976 • 70 citations

A comparison of the replication cycles of simian virus 40 in human diploid and African green monkey kidney cells

1966 • 69 citations

Cloning and characterization of the integrated viral DNA from three lines of SV40-transformed mouse cells

1981 • 66 citations

SV40‐transformed human fibroblasts: Evidence for cellular aging in precrisis cells

1985 • 66 citations

The generation of human monocyte/macrophage cell lines

1983 • 58 citations

Efficient Transfer of Cloned DNA into Human Diploid Cells: Protoplast Fusion in Suspension

1984 • 50 citations

Immortalization of xeroderma pigmentosum cells by simian virus 40 DNA having a defective origin of DNA replication

1986 • 49 citations

Susceptibility of Human Cell Strains to Transformation by Simian Virus 40 and Simian Virus 40 Deoxyribonucleic Acid

1970 • 42 citations

Induction of gene mutations and chromosomal aberrations by simian virus 40 in cultured mammalian cells

1975 • 42 citations

Mutagenesis by simian virus 40. I. Detection of mutations in Chinese hamster cell lines using different resistance markers

1976 • 41 citations

Human fibroblasts transformed by the early region of SV40 DNA: Analysis of “free” viral DNA sequences

1980 • 40 citations

Stabilization of the 53,000-Dalton Nonviral Tumor Antigen Is Not Required for Transformation by Simian Virus 40

1983 • 37 citations

Comparison of Transformation and T Antigen Induction in Human Cell Lines

1970 • 35 citations

SV40-Transformed Human Diploid Cells that Remain Transformed throughout Their Limited Lifespan

1979 • 31 citations

Rearrangements of host and viral DNA in mouse cells transformed by Simian virus 40

1984 • 31 citations

Replication of simian virus 40 DNA in normal human fibroblasts and in fibroblasts from xeroderma pigmentosum

1981 • 28 citations

Efficient Transformation of Human Fibroblasts by Adenovirus-Simian Virus 40 Recombinants

1984 • 26 citations

Cytogenetic changes induced in human diploid fibroblasts by tsA58 SV40 at permissive and restrictive temperatures

1985 • 23 citations

A frameshift mutation affecting the carboxyl terminus of the simian virus 40 large tumor antigen results in a replication- and transformation-defective virus.

1983 • 22 citations

Expression of transformation in cell hybrids. II. Nonsuppression of the transformed phenotype in hybrids between a chemically transformed and nontransformed derivatives of Balb/3T3

1978 • 17 citations

Differential replication of SV40 and polyoma DNAs in Chinese hamster ovary cells

1985 • 17 citations

Genetics of SV40 T-antigen expression: Studies of twins, heritable syndromes and cancer families

1978 • 16 citations

DNA binding properties of a mutant T antigen from the simian virus 40-transformed human cell line simian virus 80

1984 • 14 citations

G-Bands without pretreatment of slides, in chemically defined conditions

1983 • 4 citations