Pharmacokinetic interaction between ritonavir and clarithromycin*

Prediction of Creatinine Clearance from Serum Creatinine

1976 • 15,066 citations

A Short-Term Study of the Safety, Pharmacokinetics, and Efficacy of Ritonavir, an Inhibitor of HIV-1 Protease

1995 • 569 citations

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

1995 • 546 citations

A Preliminary Study of Ritonavir, an Inhibitor of HIV-1 Protease, to Treat HIV-1 Infection

1995 • 484 citations

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

1996 • 342 citations

Effect of ritonavir on the pharmacokinetics of ethinyl oestradiol in healthy female volunteers

1998 • 180 citations

Metabolism and disposition of clarithromycin in man.

1990 • 129 citations

Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.

1997 • 120 citations

Simultaneous determination of clarithromycin and 14(R)-hydroxyclarithromycin in plasma and urine using high-performance liquid chromatography with electrochemical detection

1991 • 91 citations

Clarithromycin

1997 • 82 citations

Determination of ritonavir, a new HIV protease inhibitor, in biological samples using reversed-phase high-performance liquid chromatography

1997 • 75 citations

HIV protease inhibitors: their anti-HIV activity and potential role in treatment.

1993 • 67 citations

Pharmacokinetics of clarithromycin, a new macrolide, after single ascending oral doses

1992 • 65 citations

Use of a more general model for bioavailability studies

1990 • 13 citations