Clarithromycin

Medical Section pf the American Lung Association: Guidelines for the Initial Management of Adults with Community-acquired Pneumonia: Diagnosis, Assessment of Severity, and Initial Antimicrobial Therapy

1993 • 1,063 citations

Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: results of a 30-center national surveillance study

1996 • 493 citations

Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia

1995 • 345 citations

Clarithromycin

1992 • 285 citations

Epidemiology and Treatment of Chronic Bronchitis and Its Exacerbations

1995 • 251 citations

Modulatory effect of antibiotics on cytokine production by human monocytes in vitro

1996 • 210 citations

Legionnaires' Disease

1993 • 181 citations

Reduced Serum Levels Of Clarithromycin In Patients Treated With Multi-Drug Regimens Including Rifampin Or Rifabutin For Mycobacterium Avium-M. Intracellulare Infection

1995 • 180 citations

Adverse Events Associated with High-Dose Rifabutin in Macrolide-Containing Regimens for the Treatment of Mycobacterium avium Complex Lung Disease

1995 • 154 citations

Effect of clarithromycin on sputum production and its rheological properties in chronic respiratory tract infections

1995 • 140 citations

Single-dose intrapulmonary pharmacokinetics of azithromycin, clarithromycin, ciprofloxacin, and cefuroxime in volunteer subjects

1996 • 139 citations

Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state

1995 • 135 citations

Metabolism and disposition of clarithromycin in man.

1990 • 129 citations

In vitro activities of azithromycin, clarithromycin, L-ofloxacin, and other antibiotics against Chlamydia pneumoniae

1992 • 118 citations

A comparative safety and efficacy study of clarithromycin and erythromycin stearate in community-acquired pneumonia

1991 • 116 citations

In vitro susceptibility of recent North American Group A streptococcal isolates to eleven oral antibiotics

1994 • 106 citations

Intrapulmonary pharmacokinetics of clarithromycin and of erythromycin

1995 • 105 citations

Absolute bioavailability of clarithromycin after oral administration in humans

1992 • 99 citations

Overview of issues related to medical compliance with implications for the outpatient management of infectious diseases.

1994 • 98 citations

Immunomodulatory effects of three macrolides, midecamycin acetate, josamycin, and clarithromycin, on human T-lymphocyte function in vitro

1994 • 90 citations

Treatment of Community-acquired Pneumonia

1993 • 90 citations

Effects of clarithromycin on cytochrome P-450. Comparison with other macrolides.

1989 • 81 citations

Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia

1995 • 71 citations

Efficacy of clarithromycin against Mycoplasma pneumoniae

1991 • 70 citations

The in-vitro activity of new streptogramins, RP 59500, RP 57669 and RP 54476, alone and in combination

1992 • 68 citations

Comparison of azithromycin versus clarithromycin in the treatment of patients with lower respiratory tract infection

1993 • 67 citations

Clarithromycin Pharmacokinetics in Healthy Young and Elderly Volunteers

1992 • 66 citations

The comparative efficacy and safety of clarithromycin and amoxycillin in the treatment of outpatients with acute maxillary sinusitis

1991 • 66 citations

Pharmacokinetics of clarithromycin, a new macrolide, after single ascending oral doses

1992 • 65 citations

A comparison of clarithromycin with ampicillin in the treatment of outpatients with acute bacterial exacerbation of chronic bronchitis

1991 • 64 citations

Susceptibilities to clarithromycin and erythromycin of isolates of Chlamydia pneumoniae from children with pneumonia

1994 • 64 citations

Single‐ and Multiple‐dose Pharmacokinetics of Clarithromycin, a New Macrolide Antimicrobial

1993 • 64 citations

The pharmacokinetics of clarithromycin and its 14-OH metabolite

1991 • 63 citations

Clarithromycin-Induced Mania in Two Patients with AIDS

1995 • 61 citations

Comparative study of clarithromycin and ampicillin in the treatment of patients with acute bacterial exacerbations of chronic bronchitis

1991 • 59 citations

Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens

1995 • 58 citations

A comparative study of clarithromycin and penicillin VK in the treatment of outpatients with streptococcal pharyngitis

1991 • 57 citations

Resistance to drugs targeting protein synthesis in mycobacteria

1994 • 56 citations

Drug‐Food Interaction Potential of Clarithromycin, A New Macrolide Antimicrobial

1992 • 55 citations

Delirium Probably Induced by Clarithromycin in a Patient Receiving Fluoxetine

1995 • 55 citations

Clarithromycin‐Carbamazepine Interaction: A Case Report

1993 • 54 citations

In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae

1994 • 54 citations

Comparison of azithromycin versus clarithromycin in the treatment of patients with upper respiratory tract infections

1993 • 52 citations

Penetration of clarithromycin into lung tissues from patients undergoing lung resection

1994 • 49 citations

The Safety and Efficacy of Clarithromycin in Patients with Legionella Pneumonia

1991 • 49 citations

In vitro activities of a streptogramin (RP59500), three macrolides, and an azalide against four respiratory tract pathogens

1995 • 48 citations

Comparative study of clarithromycin and roxithromycin in the treatment of community-acquired pneumonia

1991 • 47 citations

The levels of clarithromycin and its 14-hydroxy metabolite in the lung

1994 • 46 citations

Efficacy and Safety of Clarithromycin Compared to Cefixime as Outpatient Treatment of Lower Respiratory Tract Infections

1993 • 46 citations

Erythromycin, clarithromycin, and azithromycin: use of frequency distribution curves, scattergrams, and regression analyses to compare in vitro activities and describe cross-resistance

1993 • 45 citations

Clarithromycin versus penicillin in the treatment of streptococcal pharyngitis

1991 • 44 citations

Clarithromycin-associated visual hallucinations in a patient with chronic renal failure on continuous ambulatory peritoneal dialysis

1996 • 44 citations

A New Model Examining Intracellular and Extracellular Activity of Amoxicillin, Azithromycin, and Clarithromycin in Infected Cells

1993 • 43 citations

Clarithromycin

1993 • 41 citations

In-vitro activity of dirithromycin in comparison with other new and established macrolides

1993 • 40 citations

Effects of clarithromycin and its metabolites on the mixed function oxidase system in hepatic microsomes of rats.

1993 • 40 citations

Comparison of the clinical and bacteriological efficacy of clarithromycin and erythromycin in the treatment of streptococcal pharyngitis

1990 • 40 citations

Clinical relevance of intracellular and extracellular concentrations of macrolides

1995 • 40 citations

Efficacy of Clarithromycin vs. Amoxicillin/Clavulanate in the Treatment of Acute Maxillary Sinusitis

1993 • 40 citations

Antimicrobial activity of ten macrolide, linsosamine and streptogramin drugs tested againstLegionella species

1992 • 40 citations

High rate of erythromycin and clarithromycin resistance among Streptococcus pneumoniae isolates from blood cultures from Providence, R.I

1993 • 39 citations

Comparative efficacy and tolerability of clarithromycin and amoxycillin in the treatment of out-patients with acute maxillary sinusitis

1990 • 38 citations

Microbiology of Chronic Maxillary Sinusitis in Adults: Isolated Aerobic and Anaerobic Bacteria and their Susceptibility to Twenty Antibiotics

1995 • 38 citations

Pharmacokinetics of clarithromycin and zidovudine in patients with AIDS

1995 • 37 citations

Overview of the safety profile of clarithromycin suspension in pediatric patients

1993 • 37 citations

THE INTERACTION BETWEEN CLARITHROMYCIN AND CYCLOSPORINE IN KIDNEY TRANSPLANT RECIPIENTS

1994 • 34 citations

Clarithromycin and Omeprazole

1996 • 34 citations

Clinical Ergotism With Lingual Ischemia Induced by Clarithromycin-Ergotamine Interaction

1996 • 33 citations

Predicting the efficacy of antimicrobial agents in respiratory infections—is tissue concentration a valid measure?

1995 • 33 citations

Comparative study of clarithromycin and penicillin V in the treatment of streptococcal pharyngitis

1991 • 32 citations

Effect of Moderate or Severe Hepatic Impairment on Clarithromycin Pharmacokinetics

1993 • 32 citations

Pharmacokinetics of a clarithromycin suspension in infants and children

1992 • 32 citations

Clinical Efficacy and Tolerance of Two New Macrolides, Clarithromycin and Josamycin, in the Treatment of Patients with Acute Exacerbations of Chronic Bronchitis

1990 • 31 citations

Macrolide pharmacokinetics and dose scheduling of roxithromycin

1992 • 30 citations

Efficacy and Safety of Clarithromycin versus Josamycin in the Treatment of Hospitalized Patients with Bacterial Pneumonia

1990 • 30 citations

Fulminant hepatic failure associated with clarithromycin.

1996 • 30 citations

Comparative safety and efficacy of clarithromycin and ampicillin in the treatment of out‐patients with acute bacterial exacerbation of chronic bronchitis

1992 • 30 citations

Comparison of clarithromycin and penicillin VK suspensions in the treatment of children with streptococcal pharyngitis and review of currently available alternative antibiotic therapies

1993 • 30 citations

In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae

1996 • 29 citations

A comparison of 5 days of dirithromycin and 7 days of clarithromycin in acute bacterial exacerbation of chronic bronchitis

1995 • 29 citations

Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers

1995 • 29 citations

Clarithromycin-Induced Digoxin Toxicity in a Patient with AIDS

1995 • 29 citations

Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch

1993 • 27 citations

Possible Role of the Intestinal P‐450 Enzyme System in a Cyclosporine‐Clarithromycin Interaction

1996 • 27 citations

Multicenter comparison of clarithromycin and amoxicillin in the treatment of acute maxillary sinusitis

1993 • 25 citations

In-vitro activity of ten antimicrobial agents against penicillin-resistant Streptococcus pneumoniae

1992 • 25 citations

A Guide to the Treatment of Lower Respiratory Tract Infections

1995 • 25 citations

Clarithromycin-carbamazepine interaction in a clinical setting.

1994 • 24 citations

In-vitro activity of six intracellular antibiotics against Legionella pneumophila strains of human and environmental origin

1994 • 23 citations

Comparative in vitro activity of clarithromycin

1992 • 22 citations

Safety and efficacy of Clarithromycin in the treatment of acute mild to moderate respiratory tract infections.

1991 • 20 citations

Clarithromycin versus cefaclor for the treatment of mild-to-moderate acute bacterial bronchitis

1993 • 19 citations

In vitro activity of cefpodoxime compared with other oral cephalosporins tested against 5556 recent clinical isolates from five medical centers

1993 • 19 citations

In vitro activity of Bay y 3118, a new quinolone

1993 • 19 citations

Comparative efficacy and safety of roxithromycin and clarithromycin in upper respiratory tract infections

1992 • 18 citations

Clarithromycin vs penicillin in the treatment of streptococcal pharyngitis.

1992 • 17 citations

Penetration of clarithromycin and its 14-hydroxy metabolite into middle ear effusion in children with secretory otitis media

1994 • 17 citations

A comparative study of clarithromycin and amoxycillin suspensions in the treatment of pediatric patients with acute otitis media

1993 • 17 citations

Immunostimulation by Clarithromycin in Healthy Volunteers and Chronic Bronchitis Patients

1993 • 17 citations

Cytomegalovirus infection and the development of cellular rejection.

1994 • 16 citations

Penetration of Clarithromycin into Human Saliva

1993 • 16 citations

Sinusitis. A review for generalists.

1995 • 15 citations

Clarithromycin versus cefaclor in lower respiratory tract infections. The Canadian Bronchitis Study Group.

1995 • 15 citations

Penetration of clarithromycin into middle ear fluid of children with acute otitis media

1997 • 15 citations

Treatment Recommendations for Respiratory Tract Infections Associated with Aging

1993 • 15 citations

Susceptibility of Legionella species to antimicrobial agents

1993 • 15 citations

Susceptibility of Streptococcus pyogenes to azithromycin, clarithromycin, erythromycin and roxithromycin in vitro

1995 • 15 citations

Cost-Effective Treatment of Lower Respiratory Tract Infections

1996 • 14 citations

The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration

1994 • 14 citations

Clarithromycin 250 mg b. i. d. for 5 or 10 days in the treatment of adult patients with purulent bronchitis

1993 • 14 citations

In vitro activity of clarithromycin, cefprozil, and other common oral antimicrobial agents against gram-positive and gram-negative pathogens.

1993 • 13 citations

[Clarithromycin versus amoxicillin-clavulanic acid in the treatment of acute maxillary sinusitis in adults].

1996 • 13 citations

Pneumonia: The Impact of Antibiotic Resistance on Its Management

1995 • 12 citations

A randomized comparative study on the safety and efficacy of clarithromycin and erythromycin in treating community-acquired pneumonia.

1995 • 12 citations

Azithromycin Compared with Clarithromycin in the Treatment of Adult Patients with Acute Purulent Tracheobronchitis: A Cost of Illness Study

1995 • 10 citations

Antibiotic utilization and cost analysis in hospitalized patients with community-acquired pneumonia.

1995 • 9 citations

Treatment with Ribavirin+Alpha Interferon in HCV Chronic Active Hepatitis Non-Responders to Interferon Alone: Preliminary Results

1995 • 9 citations

Enhanced Effect of Clarithromycin on Neutrophil Function In Vitro

1996 • 8 citations

A Single-Blind, Randomised, Comparative Study of Clarithromycin and Amoxycillin Suspensions in the Treatment of Children with Lower Respiratory Tract Infections

1993 • 6 citations

Susceptibility surveillance of U.S. respiratory pathogen isolates to newer macrolide and azalide antibiotics

1996 • 5 citations

Comparative in vitro activity of furopenem against aerobic bacteria isolated from pediatric patients

1995 • 5 citations

Kidney graft dysfunction after drug interaction between clarithromycin and cyclosporin

1996 • 5 citations

In vitro and in vivo Antibacterial Activities of Clarithromycin

1996 • 4 citations

In Vitro Susceptibility of Recently Isolated Respiratory Tract Pathogens to Minocycline and Comparable Antibiotics. A Multicentre Study.

1994 • 3 citations

[Comparative in vitro activity of new oral macrolides against Streptococcus pyogenes strains].

1993 • 3 citations

Antimicrobial activity of josamycin against erythromycin-resistant staphylococci as compared to roxythromycin and clarithromycin

1993 • 2 citations

Drug usage evaluation: clarithromycin as sequential therapy.

1993 • 1 citations