Mutant p53 protein overexpression is associated with poor outcome in patients with well or moderately differentiated ovarian carcinoma

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1992 • 27,454 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

The p53 tumour suppressor gene

1991 • 3,871 citations

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

1990 • 3,720 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Cancer of the Ovary

2004 • 2,075 citations

Clinical Implications of the p53 Tumor-Suppressor Gene

1993 • 1,341 citations

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

1990 • 1,080 citations

Cell Proliferation in Carcinogenesis

1990 • 1,063 citations

Association of p53 Protein Expression With Tumor Cell Proliferation Rate and Clinical Outcome in Node-Negative Breast Cancer

1993 • 777 citations

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

1992 • 757 citations

TP53 tumor suppressor gene: A model for investigating human mutagenesis

1992 • 584 citations

Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products

1991 • 556 citations

An immunochemical analysis of the human nuclear phosphoprotein p53

1992 • 533 citations

p53 Protein Accumulation and Gene Mutation in the Progression of Human Prostate Carcinoma

1993 • 488 citations

Overexpression and mutation of p53 in epithelial ovarian cancer.

1991 • 464 citations

Association of Overexpression of Tumor Suppressor Protien p53 With Rapid Cell Proliferation and Poor Prognosis in Node-Negative Breast Cancer Patients

1992 • 349 citations

The tumore suppressor p53

1993 • 336 citations

p53 expression and prognosis in gastric carcinoma

1992 • 333 citations

p53 gene mutations and protein accumulation in human ovarian cancer.

1993 • 294 citations

Cancer of the Ovary

1993 • 288 citations

Genetic basis for p53 overexpression in human breast cancer.

1991 • 287 citations

Maintenance of p53 alterations throughout breast cancer progression.

1991 • 244 citations

Comparative Study of p53 Gene and Protein Alterations in Human Astrocytic Tumors

1993 • 229 citations

Overexpression and mutation of p53 in endometrial carcinoma.

1992 • 227 citations

p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.

1993 • 216 citations

Enzymically amplified time-resolved fluorescence immunoassay with terbium chelates

1992 • 216 citations

Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.

1991 • 194 citations

Spectrum of Mutation and Frequency of Allelic Deletion of the p53 Gene in Ovarian Cancer

1993 • 184 citations

p53 mutation is a common genetic event in ovarian carcinoma.

1993 • 177 citations

Mutation and overexpression of p53 in early-stage epithelial ovarian cancer.

1993 • 168 citations

Prognostic significance of p53 immunostaining in epithelial ovarian cancer.

1994 • 155 citations

p53 mutations in ovarian cancer: a late event?

1991 • 151 citations

From gene to carcinogen: a rapidly evolving field in molecular epidemiology.

1991 • 146 citations

p53 Alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes

1994 • 133 citations

Allele losses on chromosome 17 in human epithelial ovarian carcinoma.

1990 • 121 citations

High Incidence of p53 Gene Mutation in Human Ovarian Cancer and Its Association with Nuclear Accumulation of p53 Protein and Tumor DNA Aneuploidy

1992 • 101 citations

Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma

1992 • 94 citations

Quantification of p53 protein in tumor cell lines, breast tissue extracts and serum with time-resolved immunofluorometry.

1993 • 58 citations

Comparison between p53 staining in tissue sections and p53 proteins levels measured by an ELISA technique

1993 • 49 citations

Ultrasensitive Thyrotropin Immunoassay Based on Enzymatically Amplified Time-Resolved Fluorescence with a Terbium Chelate

1992 • 45 citations

Multiple labeling and time-resolvable fluorophores

1991 • 42 citations

Detection of p53 Gene Mutations in Human Ovarian and Endometrial Cancers by Polymerase Chain Reaction‐Single Strand Conformation Polymorphism Analysis

1992 • 41 citations

Human Papillomavirus-Negative Status and c-mycGene Overexpression: Independent Prognostic Indicators of Distant Metastasis for Early-Stage Invasive Cervical Cancers

1992 • 34 citations

Clinical applications of the p53 tumor suppressor gene

1995 • 15 citations

High incidence of mutations of the p53 gene detected in ovarian tumours by the use of chemical mismatch cleavage

1993 • 14 citations

Enzyme‐linked immunosorbent assay for p53 in gastrointestinal malignancy: comparison with immunohistochemistry

1993 • 9 citations

Deleted Work

1955 • 0 citations