Inhibition by various antipsychotic drugs of the G‐protein‐activated inwardly rectifying K+ (GIRK) channels expressed in Xenopus oocytes
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References (43)
Dopamine receptor pharmacology
1994 • 959 citations
The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins
1995 • 830 citations
A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation
1995 • 510 citations
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 • 472 citations
IRK(1–3) and GIRK(1–4) Inwardly Rectifying K+Channel mRNAs Are Differentially Expressed in the Adult Rat Brain
1996 • 450 citations
The inward rectifier potassium channel family
1995 • 426 citations
Ionic Channels and Their Regulation by G Protein Subunits
1990 • 413 citations
Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism
1974 • 382 citations
Abnormal Heart Rate Regulation in GIRK4 Knockout Mice
1998 • 377 citations
Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K + channel GIRK2
1997 • 336 citations
Clozapine and norclozapine plasma concentrations and clinical response of treatment-refractory schizophrenic patients [published erratum appears in Am J Psychiatry 1991 Oct;148(10):1427]
1991 • 322 citations
Drug receptors and the inhibition of nerve cells
1989 • 308 citations
Molecular Properties of Neuronal G-protein-activated Inwardly Rectifying K+ Channels
1995 • 261 citations
Heteromultimerization of G-Protein-Gated Inwardly Rectifying K+Channel Proteins GIRK1 and GIRK2 and Their Altered Expression inweaverBrain
1996 • 244 citations
Tissue Concentrations of Clozapine and its Metabolites in the Rat
1993 • 226 citations
Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.
1983 • 219 citations
Pimozide
1976 • 191 citations
Cloning of a Xenopus laevis Inwardly Rectifying K+ Channel Subunit That Permits GIRK1 Expression of IKACh Currents in Oocytes
1996 • 176 citations
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.
1968 • 164 citations
Molecular Cloning of a Mouse G-Protein-Activated K+ Channel (mGIRK1) and Distinct Distributions of 3 GIRK (GIRK1, 2 and 3) mRNAs in Mouse Brain
1995 • 161 citations
Developments in the drug treatment of schizophrenia
1992 • 154 citations
Heterologous Multimeric Assembly Is Essential for K+ Channel Activity of Neuronal and Cardiac G-Protein-Activated Inward Rectifiers
1995 • 153 citations
Cardiotoxicity More Common in Thioridazine Overdose than with Other Neuroleptics
1995 • 145 citations
Functional coupling of the nociceptin/orphanin FQ receptor with the G-protein-activated K+ (GIRK) channel
1997 • 120 citations
ECG changes during haloperidol and pimozide treatment of Tourette's disorder
1987 • 118 citations
Psychotropic drug block voltage-gated ion channels in neuroblastoma cells
1989 • 89 citations
Subtype-selective inhibition of N-methyl-D-aspartate receptors by haloperidol.
1996 • 88 citations
Functional Couplings of the δ- and the κ-Opioid Receptors with the G-Protein-Activated K+ Channel
1995 • 73 citations
Blood to brain distribution of neuroleptics
1987 • 63 citations
Haloperidol: twenty years' clinical experience.
1978 • 52 citations
Effects of thioridazine and its metabolites on dopaminergic function: drug metabolism as a determinant of the antidopaminergic actions of thioridazine.
1984 • 40 citations
Plasma levels and half lives of thioridazine and some of its metabolites
1977 • 40 citations
Comparison of the Three Mouse G‐Protein‐Activated K+ (GIRK) Channels and Functional Couplings of the Opioid Receptors with the GIRKI Channela
1996 • 37 citations
Plasma pimozide profiles in chronic schizophrenics.
1979 • 36 citations
Long-term experience with clozapine in Denmark: research and clinical practice
1989 • 31 citations
Neuroleptic Serum Levels Measured by Radioreceptor Assay and Clinical Response in Schizophrenic Patients
1981 • 31 citations
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. II. Kinetic study of the distribution of pimozide and metabolites in brain, liver, and blood of the Wistar rat.
1968 • 28 citations
Partial Structure, Chromosome Localization, and Expression of the MouseIclnGene
1997 • 26 citations
Effects of clozapine on the δ‐ and κ‐opioid receptors and the G‐protein‐activated K+ (GIRK) channel expressed in Xenopus oocytes
1998 • 24 citations
Partial Structure, Chromosome Localization, and Expression of the MouseGirk4Gene
1997 • 22 citations
High Doses of Haloperidol in Schizophrenia
1982 • 18 citations
Antipsychotic medications and seizures.
1991 • 17 citations
Opposing Anticholinergic and Cardio-depressive Effects of Promazine and Thioridazine in Isolated Rat Atria
1972 • 4 citations