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An Enhancer Element in the EphA2 (Eck) Gene Sufficient for Rhombomere-specific Expression Is Activated by HOXA1 and HOXB1 Homeobox Proteins

Data up to Jan 2025

Published1998
Citations99
References39

Total Citations Per Year

Abstract

References (39)

Manipulating the mouse embryo: A laboratory manual

1986 • 2,165 citations

Hox genes in vertebrate development

1994 • 2,057 citations

Patterning the Vertebrate Neuraxis

1996 • 1,151 citations

Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

1996 • 851 citations

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

1995 • 849 citations

Segmental patterns of neuronal development in the chick hindbrain

1989 • 840 citations

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

1995 • 740 citations

Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions

1990 • 685 citations

Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System

1996 • 536 citations

A distinct Hox code for the branchial region of the vertebrate head

1991 • 503 citations

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

1995 • 493 citations

Eph Family Transmembrane Ligands Can Mediate Repulsive Guidance of Trunk Neural Crest Migration and Motor Axon Outgrowth

1997 • 477 citations

Topographically Specific Effects of ELF-1 on Retinal Axon Guidance In Vitro and Retinal Axon Mapping In Vivo

1996 • 418 citations

Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1

1996 • 410 citations

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

1996 • 393 citations

Interactions of Eph-related receptors and ligands confer rostrocaudal pattern to trunk neural crest migration

1997 • 389 citations

The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells

1997 • 343 citations

Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain

1993 • 340 citations

Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch

1998 • 317 citations

Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain

1995 • 315 citations

Genetic interactions betweenHoxa1andHoxb1reveal new roles in regulation of early hindbrain patterning

1998 • 311 citations

Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm

1990 • 300 citations

Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve

1996 • 282 citations

Expression of the mouse labial-Alike homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain

1991 • 239 citations

A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm

1992 • 226 citations

Distinct and Overlapping Expression Patterns of Ligands for Eph-Related Receptor Tyrosine Kinases during Mouse Embryogenesis

1996 • 215 citations

Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain

1989 • 214 citations

Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis.

1994 • 174 citations

Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20

1998 • 147 citations

Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain

1994 • 135 citations

Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos.

1993 • 133 citations

Functional dissection of a transcriptionally active, target-specific Hox-Pbx complex

1997 • 104 citations

The expression of the receptor-protein tyrosine kinase gene, eck, is highly restricted during early mouse development

1994 • 98 citations

Enhancer analysis of the mouse HNF‐3β gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub‐ elements

1996 • 94 citations

The Expression Pattern of the Mouse Receptor Tyrosine Kinase Gene MDK1 Is Conserved through Evolution and Requires Hoxa-2 for Rhombomere-Specific Expression in Mouse Embryos

1996 • 88 citations

The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development.

1994 • 78 citations

Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion.

1996 • 60 citations

Isolation and analysis of embryonic expression of Hox-4.9, a member of the murine labial-like gene family

1992 • 42 citations

Transcriptional specificity of the pluripotent embryonic stem cell.

1996 • 38 citations

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