Potential role ofbcl-2 as a suppressor of tumour angiogenesis in non-small-cell lung cancer

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1993 • 3,111 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1993 • 1,692 citations

Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1

1994 • 1,460 citations

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.

1996 • 1,045 citations

Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes.

1993 • 1,044 citations

Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer

1992 • 822 citations

Prevention of Programmed Cell Death of Sympathetic Neurons by the bcl-2 Proto-Oncogene

1992 • 724 citations

bcl-2 Protein in Non-Small-Cell Lung Carcinoma

1993 • 684 citations

Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

1994 • 664 citations

Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression.

1994 • 453 citations

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria.

1996 • 411 citations

Bcl-2 protein expression and long-term survival in breast cancer.

1994 • 404 citations

Expression of bcl-2 Protein, an Inhibitor of Apoptosis, and Bax, an Accelerator of Apoptosis, in Ventricular Myocytes of Human Hearts With Myocardial Infarction

1996 • 367 citations

bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer

1994 • 326 citations

Epidermal growth factor receptors in non-small cell lung cancer

1987 • 326 citations

c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle.

1994 • 210 citations

Characterization of Radiation-induced Apoptosis in the Small Intestine and Its Biological Implications

1994 • 202 citations

Bcl-2 protein: a prognostic factor inversely correlated to p53 in non-small-cell lung cancer

1995 • 201 citations

PROGNOSTIC VALUE OF ANGIOGENESIS IN OPERABLE NON-SMALL CELL LUNG CANCER

1996 • 176 citations

Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity.

1993 • 163 citations

c-erbB-2 Gene Product Associates with Catenins in Human Cancer Cells

1994 • 162 citations

p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients.

1996 • 157 citations

The relationship of p53 immunostaining to survival in carcinoma of the lung

1992 • 147 citations

NCL‐CB11, a new monoclonal antibody recognizing the internal domain of the c‐erbB‐2 oncogene protein effective for use on formalin‐fixed, paraffin‐embedded tissue

1990 • 108 citations

The role of endogenous nitric oxide and platelet-activating factor in hypoxia-induced intestinal injury in rats

1994 • 98 citations

Ki‐67 immunostaining and survival in operable lung cancer

1991 • 88 citations

Pattern of expression of c-erbB-2 oncoprotein in human fetuses

1989 • 70 citations

Inverse correlation between the expression of bcl-2 and p53 proteins in primary gastric lymphoma

1996 • 68 citations

Bronchial Epithelial Cells Produce Chemotactic Activity for Bronchial Epithelial Cells: Possible Role for Fibronectin in Airway Repair

1990 • 64 citations

Expression of the BCL-2 protein in normal and dysplastic bronchial epithelium and in lung carcinomas

1995 • 61 citations

Keratinocyte induced chemotaxis in the pathogenesis of Paget's disease of the breast

1994 • 40 citations

C-erbB-2 oncoprotein expression in operable non-small cell lung cancer.

1996 • 35 citations