Pattern of expression of c-erbB-2 oncoprotein in human fetuses

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.

1985 • 607 citations

Differential expression of myc family genes during murine development

1986 • 542 citations

Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

1982 • 540 citations

OVEREXPRESSION OF THE c-erbB-2 ONCOPROTEIN IN HUMAN BREAST CARCINOMAS: IMMUNOHISTOLOGICAL ASSESSMENT CORRELATES WITH GENE AMPLIFICATION

1987 • 409 citations

Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies

1985 • 408 citations

AMPLIFICATION OF c-erbB-2 ONCOGENE IN HUMAN ADENOCARCINOMAS IN VIVO

1986 • 400 citations

Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.

1985 • 391 citations

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.

1987 • 335 citations

Coexpression of the sis and myc proto-oncogenes in developing human placenta suggests autocrine control of trophoblast growth

1985 • 328 citations

pp60c-src is developmentally regulated in the neural retina

1984 • 299 citations

Neural Tissues Express High Levels of the Cellular src Gene Product pp60^c-src

1983 • 288 citations

Developmental expression of transforming growth factors alpha and beta in mouse fetus.

1988 • 272 citations

Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue.

1988 • 251 citations

Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen.

1986 • 231 citations

Expression of ras proto-oncogene proteins in normal human tissues.

1987 • 216 citations

Association of multiple copies of the c-erbB-2 oncogene with spread of breast cancer.

1987 • 214 citations

Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.

1986 • 211 citations

Expression of the c‐erbB‐2 protein in normal and transformed cells

1987 • 197 citations

Tissue and cell type-specific expression of two human c-onc genes

1983 • 182 citations

Characterization of a microvillous membrane preparation from human placental syncytiotrophoblast: A morphologic, biochemical, and physiologic study

1977 • 167 citations

Stage- and tissue-specific expression of the neu oncogene in rat development.

1987 • 163 citations

Differential Expression of Transforming Growth Factor-α during Prenatal Development of the Mouse

1985 • 138 citations

Sporadic amplification of the HER2/neu protooncogene in adenocarcinomas of various tissues.

1988 • 134 citations

Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea.

1987 • 107 citations

Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue specific and developmentally regulated expression.

1986 • 100 citations

Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector.

1987 • 98 citations

Immunohistochemical detection of the neu protein in tissue sections of human breast tumors with amplified neu DNA.

1988 • 92 citations

Characterization of the promoter region of the human c-erbB-2 protooncogene.

1987 • 87 citations

Human HER2 (neu) promoter: evidence for multiple mechanisms for transcriptional initiation.

1987 • 77 citations

Amplification of the neu (c-erbB-2) Oncogene in Human Mammmary Tumors is Relatively Frequent and is Often Accompanied by Amplification of the Linked c-erbA Oncogene

1987 • 74 citations

Abnormalities of protooncogenes in non-small cell lung cancer. Correlations with tumor type and clinical characteristics

1987 • 67 citations

Proto-Oncogene c-ros Codes for a Molecule with Structural Features Common to Those of Growth Factor Receptors and Displays Tissue-Specific and Developmentally Regulated Expression

1986 • 34 citations

Differential expression of transforming growth factor-alpha during prenatal development of the mouse.

1985 • 34 citations

Development of nitrosourea-induced brain tumours—With a special note on changes occurring during latency

1986 • 31 citations

Human HER2 (neu) Promoter: Evidence for Multiple Mechanisms for Transcriptional Initiation

1987 • 29 citations

Epidermal growth factor receptor expression in human foetal tissues is age-dependent

1988 • 27 citations

Antibodies to the ATP-binding site of the human epidermal growth factor (EGF) receptor as specific inhibitors of EGF-stimulated protein-tyrosine kinase activity

1986 • 26 citations