Activation of a novel human transforming gene, ret, by DNA rearrangement

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Nucleotide sequence of the rightward operator of phage lambda.

1975 • 2,068 citations

The differentiation and function of human T lymphocytes

1980 • 1,548 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1984 • 1,153 citations

Molecular cloning of a new transforming gene from a chemically transformed human cell line

1984 • 966 citations

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1982 • 928 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

1982 • 775 citations

Translocations Among Antibody Genes in Human Cancer

1983 • 736 citations

Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

1982 • 706 citations

Cellular Transforming Genes

1982 • 622 citations

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1982 • 617 citations

Structure and activation of the human N-ras gene

1983 • 538 citations

Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

1982 • 494 citations

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1

1983 • 441 citations

Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene

1983 • 385 citations

Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1

1983 • 377 citations

Packaging recombinant DNA molecules into bacteriophage particles in vitro.

1977 • 343 citations

Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.

1981 • 302 citations

Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line.

1983 • 290 citations

Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.

1982 • 268 citations

Activation of the Transforming Potential of a Normal Cell Sequence: A Molecular Model for Oncogenesis

1981 • 246 citations

Gene Product of v- fgr onc : Hybrid Protein Containing a Portion of Actin and a Tyrosine-Specific Protein Kinase

1984 • 240 citations

Transforming activity of DNA of chemically transformed and normal cells

1980 • 234 citations

New human transforming genes detected by a tumorigenicity assay.

1984 • 217 citations

Identification and molecular cloning of the human Blym transforming gene activated in Burkitt's lymphomas

1983 • 192 citations

Stage-specific transforming genes of human and mouse B- and T-lymphocyte neoplasms

1982 • 175 citations

Activation of related transforming genes in mouse and human mammary carcinomas.

1981 • 139 citations

A novel transforming gene in a human malignant melanoma cell line

1984 • 135 citations

Identification of a clonally restricted 90 kD heterodimer on two human cloned natural killer cell lines. Its role in cytotoxic effector function.

1983 • 115 citations

Malignant Lymphomas: Etiology, Immunology, Pathology, Treatment

1982 • 108 citations

Characterization of human transforming genes from chemically transformed, teratocarcinoma, and pancreatic carcinoma cell lines.

1984 • 105 citations

Transformation of NIH/3T3 mouse cells by DNA of Rous sarcoma virus

1979 • 77 citations

Transformation by subgenomic fragments of Rous sarcoma virus DNA

1980 • 45 citations

Co-transfection of normal NIH/3T3 DNA and retroval LTR sequences: a novel strategy for the detection of potential c-onc genes.

1984 • 36 citations

Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas.

1984 • 35 citations

Transformation of human cells by DNAs ineffective in transformation of NIH 3T3 cells.

1985 • 26 citations

Unstable transformation of mouse 3T3 cells by transfection with DNA from normal human lymphocytes.

1984 • 26 citations

Leukaemia virus infection promotes fibroblast transformation by normal BALB/c mouse DNA

1980 • 15 citations

Transformation of NIH 3T3 cells by DNA of the MCF-7 human mammary carcinoma cell line induces expression of an endogenous murine leukemia provirus.

1984 • 4 citations