CD8 ⁺ T Cell Cross-Priming via Transfer of Proteasome Substrates

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

1976 • 951 citations

Interaction of Heat Shock Proteins with Peptides and Antigen Presenting Cells: Chaperoning of the Innate and Adaptive Immune Responses

2002 • 845 citations

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8–9 residues

2002 • 486 citations

Producing Nature’s Gene-Chips: The Generation of Peptides for Display by MHC Class I Molecules

2002 • 309 citations

Mechanisms of Exogenous Antigen Presentation by MHC Class I Molecules in Vitro and in Vivo: Implications for Generating CD8+ T Cell Responses to Infectious Agents, Tumors, Transplants, and Vaccines

1999 • 293 citations

Characterization of the ovalbumin‐specific TCR transgenic line OT‐I: MHC elements for positive and negative selection

2000 • 279 citations

Processing of engulfed apoptotic bodies yields T cell epitopes.

1997 • 267 citations

Antigen processing in vivo and the elicitation of primary CTL responses.

1995 • 226 citations

A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line.

1994 • 225 citations

The Genetic Control of HLA‐A and B Antigens in Somatic Cell Hybrids: Requirement for β₂ Microglobulin

1978 • 222 citations

Cellular protein is the source of cross-priming antigenin vivo

2004 • 190 citations

Antigen Bias in T Cell Cross-Priming

2004 • 184 citations

Bone Marrow–Derived Antigen-Presenting Cells Are Required for the Generation of Cytotoxic T Lymphocyte Responses to Viruses and Use Transporter Associated with Antigen Presentation (Tap)-Dependent and -Independent Pathways of Antigen Presentation

2000 • 138 citations

HSP70 Peptide Binding Mutants Separate Antigen Delivery from Dendritic Cell Stimulation

2004 • 122 citations

MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies.

1997 • 110 citations

Intercellular transfer of antigen‐presenting cell determinants onto T cells: molecular mechanisms and biological significance

2002 • 103 citations

Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells

1997 • 96 citations

Generating MHC class I ligands from viral gene products

1999 • 63 citations

Cutting Edge: Efficient MHC Class I Cross-Presentation during Early Vaccinia Infection Requires the Transfer of Proteasomal Intermediates between Antigen Donor and Presenting Cells

2003 • 54 citations

Cross-priming of CTL responses in vivo does not require antigenic peptides in the endoplasmic reticulum of immunizing cells.

1998 • 44 citations

Cutting Edge: Cross-Priming of CTL Responses In Vivo Does Not Require Antigenic Peptides in the Endoplasmic Reticulum of Immunizing Cells

1998 • 34 citations