Central and Peripheral Signaling Mechanisms Involved in Endocannabinoid Regulation of Feeding: A Perspective on the Munchies

Central nervous system control of food intake

2000 • 6,305 citations

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

1992 • 5,504 citations

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1995 • 2,837 citations

International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

2002 • 2,707 citations

2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

1995 • 2,122 citations

The molecular logic of endocannabinoid signalling

2003 • 1,898 citations

Leptin-regulated endocannabinoids are involved in maintaining food intake

2001 • 1,557 citations

Role of Endogenous Cannabinoids in Synaptic Signaling

2003 • 1,535 citations

Addiction

2002 • 1,444 citations

Endocannabinoid Signaling in the Brain

2002 • 1,240 citations

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis

2003 • 1,123 citations

The Need to Feed

2002 • 1,089 citations

Endocrine Regulation of Energy Metabolism: Review of Pathobiochemical and Clinical Chemical Aspects of Leptin, Ghrelin, Adiponectin, and Resistin

2004 • 1,054 citations

The endocannabinoid system and its therapeutic exploitation

2004 • 1,045 citations

Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

2000 • 983 citations

Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2‐arachidonoyl glycerol

2002 • 776 citations

Nongenomic Glucocorticoid Inhibition via Endocannabinoid Release in the Hypothalamus: A Fast Feedback Mechanism

2003 • 774 citations

Cannabinoid physiology and pharmacology: 30 years of progress

2004 • 606 citations

Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors

1997 • 605 citations

The Cannabinoid CB₁Receptor Antagonist SR141716 Increases Acrp30 mRNA Expression in Adipose Tissue of Obese fa/fa Rats and in Cultured Adipocyte Cells

2003 • 604 citations

CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity

2004 • 575 citations

A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding

2002 • 489 citations

Cannabinoids Enhance Subsecond Dopamine Release in the Nucleus Accumbens of Awake Rats

2004 • 330 citations

Cannabinoids Modulate Synaptic Strength and Plasticity at Glutamatergic Synapses of Rat Prefrontal Cortex Pyramidal Neurons

2000 • 285 citations

Expression of Cannabinoid CB1 Receptors by Vagal Afferent Neurons Is Inhibited by Cholecystokinin

2004 • 272 citations

SR 141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset.

1998 • 272 citations

Mind versus metabolism in the control of food intake and energy balance

2004 • 254 citations

Prefrontal Cortex Stimulation Induces 2-Arachidonoyl-Glycerol-Mediated Suppression of Excitation in Dopamine Neurons

2004 • 245 citations

Encoding of Palatability and Appetitive Behaviors by Distinct Neuronal Populations in the Nucleus Accumbens

2005 • 214 citations

Cannabinoid signaling in glial cells

2004 • 210 citations

β-Adrenergic Receptors, Diet-induced Thermogenesis, and Obesity

2003 • 171 citations

Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain

2004 • 140 citations

Down-regulation of cannabinoid-1 (CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: a role for endogenous cannabinoids in driving appetite for palatable food?

2002 • 129 citations

Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain

2003 • 121 citations

Cannabinoids suppress synaptic input to neurones of the rat dorsal motor nucleus of the vagus nerve

2004 • 118 citations

CB₁ Receptors in the Preoptic Anterior Hypothalamus Regulate WIN 55212-2 [(4,5-Dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1ij]quinolin-6-one]-Induced Hypothermia

2002 • 104 citations

Addicting drugs utilize a synergistic molecular mechanism in common requiring adenosine and Gi-βγ dimers

2003 • 84 citations

Endocannabinoids and food consumption: comparisons with benzodiazepine and opioid palatability-dependent appetite

2004 • 79 citations

Exogenous and Endogenous Cannabinoids Control Synaptic Transmission in Mice Nucleus Accumbens

2003 • 73 citations