Back to search

Effects of medial prefrontal or anterior cingulate cortex lesions on responding for cocaine under fixed-ratio and second-order schedules of reinforcement in rats

Data up to Jan 2025

Published1997
Citations188
References80

Total Citations Per Year

Abstract

References (80)

Statistical principles in experimental design.

1962 • 27,228 citations

Brain Maps: Structure of the Rat Brain

1992 • 1,873 citations

The rat brain in stereotaxic coordinates (2nd edn)

1987 • 1,743 citations

Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin

1989 • 1,570 citations

The organization of the projection from the cerebral cortex to the striatum in the rat

1989 • 1,334 citations

Activation of memory circuits during cue-elicited cocaine craving.

1996 • 939 citations

Reinstatement of cocaine-reinforced responding in the rat

1981 • 936 citations

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1992 • 832 citations

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

1980 • 736 citations

Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET

1997 • 707 citations

Pathophysiological Basis of Vulnerability to Drug Abuse: Role of an Interaction Between Stress, Glucocorticoids, and Dopaminergic Neurons

1996 • 671 citations

Involvement of the amygdala in stimulus-reward associations: Interaction with the ventral striatum

1989 • 662 citations

The Cortex of the Rat: A Stereotaxic Atlas

1985 • 658 citations

Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

1984 • 644 citations

The Cerebral Cortex of the Rat and Visual Attentional Function: Dissociable Effects of Mediofrontal, Cingulate, Anterior Dorsolateral, and Parietal Cortex Lesions on a Five-Choice Serial Reaction Time Task

1996 • 510 citations

Chapter 5 The anatomical relationship of the prefrontal cortex with the striatopallidal system, the thalamus and the amygdala: evidence for a parallel organization

1991 • 506 citations

Changes in brain glucose metabolism in cocaine dependence and withdrawal

1991 • 460 citations

Conditioned responses to cocaine-related stimuli in cocaine abuse patients

1992 • 457 citations

Interactions between the amygdala and ventral striatum in stimulus-reward associations: Studies using a second-order schedule of sexual reinforcement

1989 • 455 citations

Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats

1982 • 451 citations

6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine

1994 • 420 citations

The Prefrontal Cortex Regulates the Basal Release of Dopamine in the Limbic Striatum: An Effect Mediated by Ventral Tegmental Area

1996 • 365 citations

Ventral frontal deficits in psychopathy: Neuropsychological test findings

1995 • 364 citations

Brainstem innervation of prefrontal and anterior cingulate cortex in the rhesus monkey revealed by retrograde transport of HRP

1982 • 353 citations

Dopaminergic activity is reduced in the prefrontal cortex and increased in the nucleus accumbens of rats predisposed to develop amphetamine self-administration

1991 • 335 citations

Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors

1995 • 316 citations

Corticosterone in the range of stress-induced levels possesses reinforcing properties: implications for sensation-seeking behaviors.

1993 • 315 citations

Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress

1990 • 308 citations

Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement.

1996 • 301 citations

Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions ofd-amphetamine

1993 • 296 citations

Attention and the frontal cortex as examined by simultaneous temporal processing

1988 • 263 citations

Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists

1995 • 263 citations

A MATHEMATICAL INDEX OF PERFORMANCE ON FIXED‐INTERVAL SCHEDULES OF REINFORCEMENT

1960 • 247 citations

Effect of 6‐Hydroxydopamine Lesions of the Medial Prefrontal Cortex on Neurotransmitter Systems in Subcortical Sites in the Rat

1980 • 242 citations

Working memory, response selection, and effortful processing in rats with medial prefrontal lesions.

1994 • 227 citations

The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat

1990 • 223 citations

Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey.

1973 • 213 citations

Effects of lesions to amygdala, ventral subiculum, medial prefrontal cortex, and nucleus accumbens on the reaction to novelty: Implications for limbic--striatal interactions.

1996 • 197 citations

Amphetamine-type reinforcement by dopaminergic agonists in the rat

1978 • 182 citations

Reinforcing properties of cocaine in the medial prefrontal cortex: Primary action on presynaptic dopaminergic terminals

1986 • 169 citations

A learning model of addiction.

1992 • 159 citations

Supersensitivity to the reinforcing effects of cocaine following 6-hydroxydopamine lesions to the medial prefrontal cortex in rats

1991 • 144 citations

Partial dopamine depletion of the prefrontal cortex leads to enhanced mesolimbic dopamine release elicited by repeated exposure to naturally reinforcing stimuli

1992 • 141 citations

Effects of dopamine depletions in the medial prefrontal cortex on DRL performance and motor activity in the rat

1994 • 138 citations

Effects of medial dorsal thalamic and ventral pallidal lesions on the acquisition of a conditioned place preference: Further evidence for the involvement of the ventral striatopallidal system in reward-related processes

1993 • 132 citations

Two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat

1993 • 130 citations

Effect of ibotenic acid lesions of the medial prefrontal cortex on amphetamine-induced locomotion and regional brain catecholamine concentrations in the rat

1990 • 128 citations

Dissociable effects of anterior and posterior cingulate cortex lesions on the acquisition of a conditional visual discrimination: Facilitation of early learning vs. impairment of late learning

1996 • 125 citations

Cocaine Addiction:

1996 • 123 citations

Role of prefrontal cortex and striatal output systems in short-term memory deficits associated with ageing, basal forebrain lesions, and cholinergic-rich grafts.

1990 • 123 citations

Isolation rearing enhances the locomotor response to cocaine and a novel environment, but impairs the intravenous self-administration of cocaine

1994 • 121 citations

Studies of instrumental behavior with sexual reinforcement in male rats (Rattus norvegicus): I. Control by brief visual stimuli paired with a receptive female.

1987 • 116 citations

6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence intravenous self-administration of cocaine

1986 • 115 citations

Schizophrenia and psychostimulant abuse: a review and re-analysis of clinical evidence

1995 • 93 citations

Similar effects ofd-amphetamine and cocaine on extracellular dopamine levels in medial prefrontal cortex of rats

1990 • 89 citations

Effect of 6-hydroxydopamine lesions of the medial prefrontal cortex on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement

1996 • 88 citations

Effect of medial prefrontal cortex injections of SCH 23390 on intravenous cocaine self-administration under both a fixed and progressive ratio schedule of reinforcement

1995 • 86 citations

Retrospective and prospective coding of information: role of the medial prefrontal cortex

1989 • 85 citations

Behavior maintained under a second-order schedule by intramuscular injection of morphine or cocaine in rhesus monkeys.

1976 • 84 citations

Designing studies of drug conditioning in humans

1992 • 80 citations

Enhancement of drug-seeking behavior by environmental stimuli associated with cocaine or morphine injections

1979 • 76 citations

Lesions of dopamine neurons in the medial prefrontal cortex: Effects on self-administration of amphetamine and dopamine synthesis in the brain of the rat

1987 • 71 citations

Effects of 6-hydroxydopamine lesions of the prefrontal cortex on tyrosine hydroxylase activity in mesolimbic and nigrostriatal dopamine systems

1992 • 67 citations

Chemical Interactions in Methamphetamine Reinforcement

1968 • 66 citations

Frontal cortex, timing and memory

1989 • 65 citations

FIXED‐INTERVAL RESPONDING UNDER SECOND‐ORDER SCHEDULES OF FOOD PRESENTATION OR COCAINE INJECTION1

1977 • 65 citations

Behavior maintained under second-order schedules of intravenous morphine injection in squirrel and rhesus monkeys

1977 • 65 citations

Bromocriptine and cocaine cue reactivity in cocaine‐dependent patients

1992 • 62 citations

Contrasting effects of excitotoxic lesions of the prefrontal cortex on the behavioural response to d-amphetamine and presynaptic and postsynaptic measures of striatal dopamine function in monkeys

1997 • 58 citations

Stimulus-bound perseveration after frontal ablations in marmosets

1993 • 56 citations

Response-related deficits following unilateral lesions of the medial agranular cortex of the rat.

1991 • 42 citations

Effect of 6-hydroxydopamine lesions of the amygdala on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement

1994 • 36 citations

Cortical and ventral tegmental systems exert opposing influences on self-stimulation from the prefrontal cortex

1985 • 34 citations

Cocaine facilitation of prefrontal cortex self-stimulation: a microstructural and pharmacological analysis

1992 • 28 citations

Cocaine facilitates prefrontal cortex self-stimulation

1990 • 23 citations

Monoaminergic-Dependent Cognitive Functions of the Prefrontal Cortex in Monkey and Man

1994 • 21 citations

SEPARATING THE REINFORCING AND DISCRIMINATIVE PROPERTIES OF BRIEF‐STIMULUS PRESENTATIONS IN SECOND‐ORDER SCHEDULES

1979 • 18 citations

Frontal lesions and the rate of operant behavior in the rat

1982 • 10 citations

Activation of human brain reward circuitry by cocaine observed using FMRI

1996 • 6 citations

EFFECTS OF d‐AMPHETAMINE ON RESPONDING UNDER SECOND‐ORDER SCHEDULES OF REINFORCEMENT WITH PAIRED AND NONPAIRED BRIEF STIMULI

1991 • 5 citations

Cited By (0)

Loading...
Effects of medial prefrontal or anterior cingulate cortex lesions on responding for… (1997) – Psychopharmacology | Metascience Observatory Explorer