Weak anti-HIV CD8+ T-cell effector activity in HIV primary infection

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

1994 • 2,529 citations

Control of Viremia in Simian Immunodeficiency Virus Infection by CD8 ⁺ Lymphocytes

1999 • 2,206 citations

Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation

1999 • 1,912 citations

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

1994 • 1,899 citations

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

1998 • 1,890 citations

Vigorous HIV-1-Specific CD4 ⁺ T Cell Responses Associated with Control of Viremia

1997 • 1,868 citations

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

1998 • 1,426 citations

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

1999 • 1,131 citations

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1996 • 1,041 citations

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

1998 • 1,012 citations

Quantitation of HIV-1 RNA in Plasma Predicts Outcome after Seroconversion

1995 • 922 citations

Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo

1998 • 902 citations

Analysis of a Successful Immune Response against Hepatitis C Virus

1999 • 823 citations

Acute Human Immunodeficiency Virus Type 1 Infection

1998 • 736 citations

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

1998 • 666 citations

Cytotoxic-T-Cell Responses, Viral Load, and Disease Progression in Early Human Immunodeficiency Virus Type 1 Infection

1997 • 528 citations

A Re-Evaluation of the Frequency of CD8+ T Cells Specific for EBV in Healthy Virus Carriers

1999 • 520 citations

Controlling HIV pathogenesis: the role of the noncytotoxic anti-HIV response of CD8+ T cells

1996 • 434 citations

Association between Virus-Specific Cytotoxic T-Lymphocyte and Helper Responses in Human Immunodeficiency Virus Type 1 Infection

1999 • 374 citations

Immediate Early and Early Lytic Cycle Proteins Are Frequent Targets of the Epstein-Barr Virus–induced Cytotoxic T Cell Response

1997 • 362 citations

Decay Kinetics of Human Immunodeficiency Virus-Specific Effector Cytotoxic T Lymphocytes after Combination Antiretroviral Therapy

1999 • 350 citations

Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis

1999 • 344 citations

Levels of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T-Lymphocyte Effector and Memory Responses Decline after Suppression of Viremia with Highly Active Antiretroviral Therapy

1999 • 310 citations

The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia

1997 • 282 citations

CD8+ cell anti-HIV activity correlates with the clinical state of the infected individual.

1991 • 279 citations

Emergence of CTL Coincides with Clearance of Virus During Primary Simian Immunodeficiency Virus Infection in Rhesus Monkeys

1999 • 278 citations

Frequency of Class I HLA-Restricted Anti-HIV CD8+ T Cells in Individuals Receiving Highly Active Antiretroviral Therapy (HAART)

1999 • 274 citations

HIV-1–specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy

1999 • 240 citations

An Activated CD8+ T Cell Phenotype Correlates with Anti-HIV Activity and Asymptomatic Clinical Status

1993 • 189 citations

Patterns of Immunodominance in HIV-1–specific Cytotoxic T Lymphocyte Responses in Two Human Histocompatibility Leukocyte Antigens (HLA)-identical Siblings with HLA-A*0201 Are Influenced by Epitope Mutation

1997 • 187 citations

The Effect of Commencing Combination Antiretroviral Therapy Soon after Human Immunodeficiency Virus Type 1 Infection on Viral Replication and Antiviral Immune Responses

1999 • 181 citations

Depletion in blood CD11c-positive dendritic cells from HIV-infected patients

1999 • 181 citations

Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory.

1996 • 171 citations

Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection.

1998 • 156 citations

Broad, Intense Anti-Human Immunodeficiency Virus (HIV) Ex Vivo CD8⁺Responses in HIV Type 1-Infected Patients: Comparison with Anti-Epstein-Barr Virus Responses and Changes during Antiretroviral Therapy

1999 • 146 citations

Peptide binding to empty HLA-B27 molecules of viable human cells

1991 • 137 citations

Downregulation of CD28 surface antigen on CD4+ and CD8+ T lymphocytes during HIV-1 infection.

1994 • 113 citations

Lack of Viral Escape and Defective In Vivo Activation of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes in Rapidly Progressive Infection

1999 • 94 citations

Evolution of Cytotoxic T Lymphocyte Responses to Human Immunodeficiency Virus Type 1 in Patients with Symptomatic Primary Infection Receiving Antiretroviral Triple Therapy

1998 • 89 citations

Predominant involvement of CD8+CD28- lymphocytes in human immunodeficiency virus-specific cytotoxic activity

1996 • 83 citations

Comparative Analysis of Cytotoxic T Lymphocytes in Lymph Nodes and Peripheral Blood of Simian Immunodeficiency Virus-Infected Rhesus Monkeys

1999 • 81 citations

Ex vivo analysis of cytotoxic T lymphocytes to measles antigens during infection and after vaccination in Gambian children.

1998 • 78 citations

Antigen-Specific Expansion of Cytotoxic T Lymphocytes in Acute Measles Virus Infection

1999 • 49 citations

Persistent HIV-1-Specific CTL Clonal Expansion Despite High Viral Burden Post In Utero HIV-1 Infection

1999 • 40 citations

Different patterns of HIV-1-specific cytotoxic T-lymphocyte activity after primary infection

1995 • 39 citations

Different patterns of HIV-1-specific cytotoxic T-lymphocyte activity after primary infection

1995 • 36 citations

Alteredex vivo balance between CD28+ and CD28− cells within HIV-specific CD8+ T cells of HIV-seropositive patients

1999 • 36 citations

Virologic and immunologic events in primary HIV infection

1997 • 30 citations