Identification of essential sequence motifs in the node/notochord enhancer of Foxa2 (Hnf3β) gene that are conserved across vertebrate species

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 2,165 citations

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

1996 • 1,827 citations

HNF-3β is essential for node and notochord formation in mouse development

1994 • 985 citations

Requirement for Wnt3 in vertebrate axis formation

1999 • 882 citations

Requirement for LIml in head-organizer function

1995 • 801 citations

The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

1994 • 786 citations

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

1994 • 769 citations

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

1999 • 703 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro

1997 • 667 citations

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

1993 • 619 citations

Gene Targeting: A Practical Approach

1994 • 592 citations

Gene targeting: a practical approach.

1993 • 585 citations

A β-catenin/XTcf-3 complex binds to thesiamois promoter to regulate dorsal axis specification in Xenopus

1997 • 527 citations

Smad2 and Smad3 Positively and Negatively Regulate TGFβ-Dependent Transcription through the Forkhead DNA-Binding Protein FAST2

1998 • 513 citations

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

1995 • 493 citations

Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis

1997 • 455 citations

Conserved noncoding sequences are reliable guides to regulatory elements

2000 • 428 citations

From cortical rotation to organizer gene expression: toward a molecular explanation of axis specification in Xenopus

1998 • 321 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos.

1993 • 283 citations

Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

2000 • 277 citations

The Xenopus homeobox gene Twin mediates Wnt induction of Goosecoid in establishment of Spemann’s organizer

1997 • 220 citations

The vertebrate organizer: structure and molecules

1996 • 173 citations

Molecular Interactions Continuously Define the Organizer during the Cell Movements of Gastrulation

1999 • 160 citations

Activation ofSiamoisby theWntPathway

1996 • 133 citations

Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene

1996 • 125 citations

The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.

1996 • 123 citations

Early Stages of Notochord and Floor Plate Development in the Chick Embryo Defined by Normal and Induced Expression of HNF-3β

1995 • 119 citations

Evolutionary alterations of the minimal promoter for notochord-specific Brachyury expression in ascidian embryos

1999 • 103 citations

The Restricted Promoter Activity of the Liver Transcription Factor Hepatocyte Nuclear Factor 3β Involves a Cell-Specific Factor and Positive Autoactivation

1992 • 98 citations

Enhancer analysis of the mouse HNF‐3β gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub‐ elements

1996 • 94 citations

The Snail repressor establishes a muscle/notochord boundary in the Ciona embryo

1998 • 93 citations

Suppressor of Hairless ActivatesBrachyuryExpression in theCionaEmbryo

1998 • 80 citations

3 The Organizer of the Gastrulating Mouse Embryo

1999 • 39 citations

Distribution pattern of HNF‐3β proteins in developing embryos of two mammalian species, the house shrew and the mouse

1997 • 12 citations