Identification of a novel first exon in the human dystrophin gene and of a new promoter located more than 500 kb upstream of the nearest known promoter.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Duchenne Muscular Dystrophy

1995 • 1,084 citations

Transcription of the dystrophin gene in human muscle and non-muscle tissues

1988 • 733 citations

Detection of 98% of DMD/BMD gene deletions by polymerase chain reaction

1990 • 677 citations

The structural and functional diversity of dystrophin

1993 • 632 citations

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1986 • 489 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

Alternative splicing of human dystrophin mRNA generates isoforms at the carboxy terminus

1989 • 332 citations

Dystrophin abnormalities in Duchenne/Becker muscular dystrophy

1989 • 330 citations

Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.

1988 • 313 citations

Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.

1993 • 303 citations

The thalassemia syndromes: molecular basis and prenatal diagnosis in 1990.

1990 • 285 citations

An alternative dystrophin transcript specific to peripheral nerve

1993 • 280 citations

Expression of four alternative dystrophin transcripts in brain regions regulated by different promoters

1992 • 249 citations

Duchenne muscular dystrophy gene product is not identical in muscle and brain

1989 • 230 citations

ALTERNATIVE PROMOTERS IN DEVELOPMENTAL GENE EXPRESSION

1987 • 204 citations

Insertion of a 5' truncated L1 element into the 3' end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy.

1993 • 197 citations

The human alpha 1-antitrypsin gene is transcribed from two different promoters in macrophages and hepatocytes.

1987 • 196 citations

Dystrophin is transcribed in brain from a distant upstream promoter.

1991 • 191 citations

Exon Structure of the Human Dystrophin Gene

1993 • 160 citations

A physical map of 4 million bp around the Duchenne muscular dystrophy gene on the human X-chromosome

1986 • 152 citations

Exon skipping during splicing of dystrophin mRNA precursor due to an intraexon deletion in the dystrophin gene of Duchenne muscular dystrophy kobe.

1991 • 147 citations

Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues.

1992 • 146 citations

Molecular and functional analysis of the muscle-specific promoter region of the Duchenne muscular dystrophy gene.

1990 • 142 citations

Separate promoters control transcription of the human aminopeptidase N gene in myeloid and intestinal epithelial cells

1991 • 123 citations

A housekeeping type promoter, located in the 3' region of the Duchenne muscular dystrophy gene, controls the expression of Dp71, a major product of the gene

1993 • 76 citations

Duchenne Muscular Dystrophy

2015 • 75 citations

Characterization of three optional promoters in the 5′ region of the human aldolase A gene

1987 • 70 citations

Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells.

1989 • 61 citations

Medium reiteration frequency repetitive sequences in the human genome

1991 • 60 citations

Expression of the Duchenne muscular dystrophy gene products in embryonic stem cells and their differentiated derivatives.

1992 • 46 citations

Molecular and Functional Analysis of the Muscle-Specific Promoter Region of the Duchenne Muscular Dystrophy Gene

1990 • 35 citations

Mapping of dystrophin brain promoter: A deletion of this region is compatible with normal intellect

1991 • 31 citations

Alternative Promoters In Developmental Gene Expression

1987 • 19 citations

Structure of the Two Promoters of the Human lck Gene: Differential Accumulation of Two Classes of lck Transcripts in T Cells

1989 • 12 citations

Brain- and muscle-type promoters of the dystrophin gene are selected in peripheral lymphocytes and Epstein Barr virus-transformed lymphoplastoid cells

1993 • 2 citations

Deleted Work

1955 • 0 citations