Stoichiometric interaction of smg p21 with its GDPGTP exchange protein and its novel action to regulate the translocation of smg p21 between membrane and cytoplasm

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

ras GENES

1987 • 3,818 citations

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 • 1,806 citations

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1990 • 1,049 citations

A ras-related gene with transformation suppressor activity

1989 • 979 citations

Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis.

1989 • 462 citations

Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.

1988 • 334 citations

Purification and characterization from bovine brain cytosol of a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to smg p25A, a ras p21-like GTP-binding protein.

1990 • 305 citations

Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein.

1990 • 277 citations

Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor.

1990 • 268 citations

Inhibition of GTPase Activating Protein Stimulation of Ras-p21 GTPase by the K rev -1 Gene Product

1990 • 254 citations

A novel small molecular weight GTP-binding protein with the same putative effector domain as the ras proteins in bovine brain membranes. Purification, determination of primary structure, and characterization.

1988 • 185 citations

Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins.

1990 • 154 citations

Nucleotide sequence of a human cDNA encoding aras-related protein (rap1B)

1988 • 145 citations

Purification and Characterization from Bovine Brain Cytosol of Two Gtpase-Activating Proteins Specific for smg p21, a GTP-binding Protein Having the Same Effector Domain as c-ras p21s

1989 • 120 citations

Phosphorylation of smg p21, a ras p21-like GTP-binding Protein, by Cyclic AMP-dependent Protein Kinase in a Cell-free System and in Response to Prostaglandin E1 in Intact Human Platelets

1989 • 110 citations

Inhibition of the ras p21 GTPase-activating protein-stimulated GTPase activity of c-Ha-ras p21 by smg p21 having the same putative effector domain as ras p21s.

1990 • 105 citations

Small Molecular Weight GTP-binding Proteins in Human Platelet Membranes

1989 • 100 citations

Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products

1988 • 88 citations

Tissue and Subcellular Distributions of the smg-21/rap1/ Krev-1 Proteins Which Are Partly Distinct from Those of c-ras p21s

1990 • 77 citations

Localization and subcellular distribution of cellular ras gene products in rat brain

1989 • 56 citations

Guanine nucleotide binding properties of rap1 purified from human neutrophils

1990 • 53 citations

Oligomeric structure of p21 ras proteins as determined by radiation inactivation.

1988 • 53 citations

Molecular cloning of p21B and identification of p21 purified from bovine brain and human platelets as p21B

1990 • 53 citations

Effect of protein kinase A on inositide metabolism and rap 1 G-protein in human erythroleukemia cells.

1990 • 47 citations

GTPase activating proteins for the smg-21 GTP-binding protein having the same effector domain as the ras proteins in human platelets

1989 • 44 citations

Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s.

1990 • 39 citations