Inhibition of GTPase Activating Protein Stimulation of Ras-p21 GTPase by the K rev -1 Gene Product

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

1990 • 1,077 citations

Trends in the Development of Baculovirus Expression Vectors

1988 • 1,022 citations

A ras-related gene with transformation suppressor activity

1989 • 979 citations

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1989 • 881 citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

1988 • 666 citations

GTP-binding domain: three consensus sequence elements with distinct spacing.

1987 • 602 citations

Guanosine Triphosphatase Activating Protein (GAP) Interacts with the p21 ras Effector Binding Domain

1988 • 533 citations

Molecular Cloning of Two Types of GAP Complementary DNA from Human Placenta

1988 • 492 citations

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

1988 • 402 citations

Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.

1988 • 334 citations

Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site.

1986 • 287 citations

Purification of ras GTPase activating protein from bovine brain.

1988 • 255 citations

Biochemical properties of Ha-ras encoded p21 mutants and mechanism of the autophosphorylation reaction.

1988 • 196 citations

Purification and Characterization from Bovine Brain Cytosol of Two Gtpase-Activating Proteins Specific for smg p21, a GTP-binding Protein Having the Same Effector Domain as c-ras p21s

1989 • 120 citations

Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant.

1989 • 106 citations

Hydrolysis of GTP by p21NRAS, the NRAS protooncogene product, is accompanied by a conformational change in the wild-type protein: use of a single fluorescent probe at the catalytic site.

1990 • 106 citations

Small Molecular Weight GTP-binding Proteins in Human Platelet Membranes

1989 • 100 citations

GTPase activating proteins for the smg-21 GTP-binding protein having the same effector domain as the ras proteins in human platelets

1989 • 44 citations

CYCLIC NUCLEOTIDES

1977 • 30 citations