Oligomeric structure of p21 ras proteins as determined by radiation inactivation.

ras GENES

1987 • 3,818 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

Requirement for c-ras proteins during viral oncogene transformation

1986 • 680 citations

Structure of the GDP Domain of EF-Tu and Location of the Amino Acids Homologous to ras Oncogene Proteins

1985 • 626 citations

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1982 • 617 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 • 599 citations

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1983 • 553 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

1984 • 403 citations

Malignant Activation of a K- ras Oncogene in Lung Carcinoma But Not in Normal Tissue of the Same Patient

1984 • 395 citations

Signal transduction by guanine nucleotide binding proteins

1987 • 362 citations

Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus

1980 • 356 citations

Size determination of enzymes by radiation inactivation

1979 • 316 citations

Primary structure of the α-subunit of transducin and its relationship to ras proteins

1985 • 291 citations

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects.

1986 • 285 citations

Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies Between Transducin, ras , and Elongation Factors

1985 • 276 citations

The primary structure of human serum transferrin. The structures of seven cyanogen bromide fragments and the assembly of the complete structure.

1983 • 272 citations

A Model for the Tertiary Structure of p21, the Product of the ras Oncogene

1985 • 248 citations

Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation of amino acid sequence and interactions with cyclic AMP.

1982 • 229 citations

A position 12-activated H-ras oncogene in all HS578T mammary carcinosarcoma cells but not normal mammary cells of the same patient.

1984 • 207 citations

ras gene Amplification and malignant transformation.

1985 • 204 citations

Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins.

1987 • 183 citations

Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21

1984 • 144 citations

Homology between human bladder carcinoma oncogene product and mitochondrial ATP-synthase

1983 • 131 citations

The Oncogenic Activation of Human p21 ^ras by a Novel Mechanism

1986 • 130 citations

Posttranslational processing of p21 ras proteins involves palmitylation of the C-terminal tetrapeptide containing cysteine-186

1985 • 120 citations

Ras p21 proteins with high or low GTPase activity can efficiently transform NIH3T3 cells

1986 • 118 citations

Relationship of oligomerization to enzymatic and DNA-binding properties of the SV40 large T antigen

1982 • 117 citations

Sites of allosteric shift in the structure of the cyclic AMP receptor protein

1985 • 114 citations

Spontaneous activation of a human proto-oncogene.

1983 • 114 citations

Homologies in the primary structure of GTP-binding proteins: the nucleotide-binding site of EF-Tu and p21.

1984 • 109 citations

[6] Molecular weight determinations from radiation inactivation

1985 • 107 citations

Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins.

1984 • 100 citations

Effects of two major activating lesions on the structure and conformation of human ras oncogene products.

1985 • 83 citations

High resolution X-ray crystallographic analysis of a modified form of the elongation factor Tu:Guanosine diphosphate complex

1978 • 77 citations

Transformation and stimulation of DNA synthesis in NIH-3T3 cells are a titratable function of normal p21N-ras expression.

1986 • 77 citations

Prediction of the three-dimensional structure of the transforming region of the EJ/T24 human bladder oncogene product and its normal cellular homologue.

1983 • 75 citations

Guanosine nucleotide binding by highly purified Ha-ras-encoded p21 protein produced in Escherichia coli.

1984 • 71 citations

Viral Harvey ras p21 expressed in Escherichia coli purifies as a binary one-to-one complex with GDP.

1985 • 67 citations

Photoaffinity labeling with GTP of viral p21 ras protein expressed in Escherichia coli

1984 • 57 citations

Radiation target analysis of glycoproteins

1986 • 52 citations

[44] Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides

1975 • 38 citations

Molecular Size Determination of Enzymes by Radiation Inactivation

1988 • 37 citations

Deletion mutants of Harvey ras p21 protein reveal the absolute requirement of at least two distant regions for GTP-binding and transforming activities.

1986 • 35 citations

Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides is a reliable internal standard for radiation-inactivation studies of membranes in the frozen state

1985 • 26 citations

Functional size of the human asialoglycoprotein receptor as determined by radiation inactivation.

1984 • 23 citations

Functional implications of oligomerization of simian virus 40 large T antigen during lytic virus infection

1985 • 17 citations

Disaggregation and Reconstitution of Oligomeric Complexes of Simian Virus 40 Large T-Antigen

1983 • 15 citations

Monoclonal antibodies against the membrane-bound, flavin-linked D-lactate dehydrogenase of Escherichia coli: preparation, characterization, and use in immunoaffinity chromatography

1985 • 8 citations

Structural implications of cyclic AMP receptor proteins that are active without cAMP

1986 • 1 citations