Region- and cell type-specific de novo DNA methylation in cultured mammalian cells

DNA methylation and gene activity

1988 • 904 citations

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1988 • 891 citations

High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines

1990 • 709 citations

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

1989 • 655 citations

De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines.

1990 • 237 citations

A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine

1987 • 201 citations

DNA methylation and chromatin structure: a view from below

1990 • 166 citations

The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.

1988 • 96 citations

A DNA signal from the Thy-1 gene defines de novo methylation patterns in embryonic stem cells.

1990 • 76 citations

Variation in epigenetic inheritance

1990 • 73 citations

Isolation and characterisation of DNA cytosine 5-methyltransferase from human placenta

1983 • 65 citations

Primary DNA Sequence Determines Sites of Maintenance and De Novo Methylation by Mammalian DNA Methyltransferases

1986 • 65 citations

Human methylated DNA-binding protein. Determinants of a pBR322 recognition site.

1988 • 59 citations

Smooth muscle actin expression during P19 embryonal carcinoma differentiation in cell culture

1990 • 53 citations

A partial methylation profile for a CpG site is stably maintained in mammalian tissues and cultured cell lines

1989 • 44 citations

Primary DNA sequence determines sites of maintenance and de novo methylation by mammalian DNA methyltransferases.

1986 • 43 citations

DNA methylation: sequences flanking C-G pairs modulate the specificity of the human DNA methylase

1985 • 40 citations

Nucleotide-sequence-specific de novo methylation in a somatic murine cell line.

1989 • 40 citations

Related sites in human and herpesvirus DNA recognized by methylated DNA-binding protein from human placenta

1989 • 36 citations

High frequency ?switching? at the adenine phosphoribosyltransferase locus in multipotent mouse teratocarcinoma stem cells

1984 • 32 citations

De novo and maintenance DNA methylation by a mouse plasmacytoma cell DNA methyltransferase.

1988 • 27 citations

DNA methyltransferase polypeptides in mouse and human cells

1986 • 26 citations

Allelic variation linked to adenine phosphoribosyltransferase locus in mouse teratocarcinoma cell line and feral-derived mouse strains

1989 • 14 citations

Methylation of mouse adenine phosphoribosyltransferase gene is altered upon cellular differentiation and loss of phenotypic expression

1990 • 7 citations