A DNA signal from the Thy-1 gene defines de novo methylation patterns in embryonic stem cells.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Establishment in culture of pluripotential cells from mouse embryos

1981 • 8,424 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

DNA Methylation and Gene Function

1980 • 2,069 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1985 • 1,155 citations

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1988 • 891 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1985 • 668 citations

Transformation of rat cells by DNA of human adenovirus 5

1973 • 664 citations

De novo methylation and expression of retroviral genomes during mouse embryogenesis

1982 • 524 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

MspI, an isoschizomer of HpaII which cleaves both unmethylated and methylated HpaII sites

1978 • 395 citations

The somatic replication of DNA methylation

1981 • 368 citations

Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA.

1983 • 361 citations

DNA methylation, biochemistry, and biological significance

1984 • 343 citations

DNA methylation patterns Formation and function

1984 • 312 citations

Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

1984 • 305 citations

De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells.

1982 • 299 citations

Clonal inheritance of the pattern of DNA methylation in mouse cells.

1982 • 229 citations

Methylation of foreign DNA sequences in eukaryotic cells.

1980 • 190 citations

Methylation of Mouse Liver DNA Studied by Means of the Restriction Enzymes Msp I and Hpa II

1979 • 146 citations

5-Azacytidine-Induced Reactivation of a Herpes Simplex Thymidine Kinase Gene

1982 • 144 citations

3. Teratocarcinomas and Embryonic Stem Cells

2016 • 141 citations

Structure of the murine Thy-1 gene.

1985 • 118 citations

Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression.

1986 • 102 citations

Expression of transferred thymidine kinase genes is controlled by methylation.

1982 • 71 citations

Gene Methylation Patterns and Expression

1984 • 71 citations

The maintenance of methylation-free islands in transgenic mice.

1986 • 70 citations

Isolation and characterisation of DNA cytosine 5-methyltransferase from human placenta

1983 • 65 citations

Primary DNA Sequence Determines Sites of Maintenance and De Novo Methylation by Mammalian DNA Methyltransferases

1986 • 65 citations

Studies on the biological role of DNA methylation; IV. Mode of methylation of DNA in E. coli cells

1980 • 58 citations

The mouse Thy-1.2 glycoprotein gene: complete sequence and identification of an unusual promoter.

1986 • 50 citations

Primary DNA sequence determines sites of maintenance and de novo methylation by mammalian DNA methyltransferases.

1986 • 43 citations

Nucleotide-sequence-specific de novo methylation in a somatic murine cell line.

1989 • 40 citations

In vitromethylation of CpG-rich islands

1989 • 26 citations