Iron and neoplasia

Trace Elements in Human and Animal Nutrition

1963 • 4,642 citations

Iron and infection

1978 • 1,108 citations

Trace Elements in Human and Animal Nutrition

1956 • 981 citations

Cell surface proteins and malignant transformation

1976 • 713 citations

Hepatocellular carcinoma and the hepatitis B virus: evidence for a causal association.

1978 • 588 citations

Iron and Susceptibility to Infectious Disease

1974 • 576 citations

Trace element metabolism in animals - 2.

1974 • 534 citations

Effect of Bacillus Calmette-Guérin Infection on Transplanted Tumours in the Mouse

1959 • 501 citations

Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms

1980 • 494 citations

Iron and infection.

1978 • 464 citations

Anemia of Chronic Disorders

1984 • 419 citations

Primary Carcinoma of The Liver

1958 • 402 citations

Low molecular weight intracellular iron transport compounds

1977 • 389 citations

Modulation of cell surface iron transferrin receptors by cellular density and state of activation

1979 • 366 citations

Iron in Biochemistry and Medicine

1975 • 366 citations

Novel iron uptake system specified by ColV plasmids: an important component in the virulence of invasive strains of Escherichia coli

1979 • 342 citations

Iron in biochemistry and medicine.

1974 • 341 citations

Annotation: THE ANAEMIA OF CHRONIC DISORDERS

1971 • 305 citations

THE INVOLVEMENT OF LACTOFERRIN IN THE HYPOSIDEREMIA OF ACUTE INFLAMMATION

1974 • 294 citations

A plasmid associated with virulence in the marine fish pathogen Vibrio anguillarum specifies an iron-sequestering system

1980 • 291 citations

A Unifying Hypothesis Concerning the Nature of Malignant Growth

1972 • 282 citations

TRANSFERRIN AND TRANSFERRIN RECEPTORS IN CARCINOMA OF THE BREAST

1980 • 272 citations

Nucleic Acids and Metals

1959 • 270 citations

Fever and Reduced Iron: Their Interaction as a Host Defense Response to Bacterial Infection

1979 • 261 citations

Microbial Iron Metabolism

1974 • 250 citations

Long term results of venesection therapy in idiopathic haemochromatosis.

1976 • 247 citations

The Role of Iron in Bacterial Infections, with Special Consideration of Host-Tubercle Bacillus Interaction

1973 • 233 citations

Idiopathic Hemochromatosis, an Interim Report

1980 • 221 citations

Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

1978 • 206 citations

Anemia In Cancer

1958 • 195 citations

Fever: Pathogenesis, Pathophysiology, and Purpose

1979 • 195 citations

Trace Metals in Health and Disease

1980 • 191 citations

Identification of transferrin receptors on the surface of human cultured cells.

1979 • 185 citations

The critical role of iron in host-bacterial interactions.

1978 • 184 citations

ColV Plasmid-Mediated, Colicin V-Independent Iron Uptake System of Invasive Strains of Escherichia coli

1980 • 183 citations

Induction of Sarcoma in the Rat by Iron--Dextran Complex

1959 • 178 citations

Biosynthesis of Secondary Metabolites: Roles of Trace Metals

1969 • 176 citations

Trace Elements in Infectious Processes

1976 • 173 citations

Thermoregulatory mechanisms and their therapeutic implications

1980 • 173 citations

A non-transferrin-bound serum iron in idiopathic hemochromatosis

1980 • 169 citations

The binding of human lactoferrin to mouse peritoneal cells.

1976 • 164 citations

Iron Overload in Bantu Subjects

1964 • 159 citations

Ferritinaemia in cancer

1977 • 159 citations

Cancer cachexia

1979 • 154 citations

Antitumor Activity of Corynebacterium Parvum

1978 • 148 citations

Host-tumor interaction and nutrient supply

1980 • 145 citations

A novel method for the isolation and study of a magnetotactic bacterium

1978 • 141 citations

Tumor cure and cell survival after localized radiofrequency heating.

1977 • 139 citations

On the Carcinogenicity of an Iron-Dextran Complex<xref ref-type="fn" rid="FN1">2</xref>

1960 • 136 citations

Serum ferritin as a guide to therapy in neuroblastoma.

1980 • 136 citations

IRON: ITS INTRACELLULAR LOCALIZATION AND POSSIBLE ROLE IN CELL DIVISION

1970 • 133 citations

Mechanisms of metal carcinogenesis

1979 • 121 citations

Glutamate dehydrogenase: a reliable marker of liver cell necrosis in the alcoholic.

1977 • 120 citations

An abnormal membrane glycoprotein associated with malignancy in a wide range of different tumours

1978 • 117 citations

Retrodifferentiation and the Fetal Patterns of Gene Expression in Cancer

1979 • 117 citations

Iron Metabolism and its Disorders

1976 • 110 citations

Iron Deficiency Prevents Liver Toxicity of 2,3,7,8-Tetrachlorodibenzo- p -Dioxin

1979 • 110 citations

Roles of Iron in Host-Parasite Interactions

1971 • 107 citations

The role of lactoferrin in the bactericidal function of polymorphonuclear leucocytes.

1979 • 100 citations

Transferrin binding by human lymphoblastoid cell lines and other transformed cells

1980 • 100 citations

Iron salts and transferrin are specifically required for cell division of cultured 3T6 cells

1977 • 98 citations

Inducibility of Transferrin Receptors on Friend Erythroleukemic Cells

1977 • 96 citations

STUDIES OF THE ANEMIA AND IRON METABOLISM IN CANCER 1

1956 • 96 citations

EFFECTS OF IRON DEFICIENCY EXCLUSIVE OF ANAEMIA

1978 • 95 citations

Cirrhosis and hepatoma occurring at Boston city hospital (1917-1968)

1973 • 92 citations

Clinical studies of fever and infection in cancer

1960 • 89 citations

Differential temperature sensitivity of normal and cancer cells in culture

1970 • 88 citations

Enhancement of the chromosome-damaging action of ascorbate by transition metals.

1979 • 87 citations

Ferritin Synthesis by Human T Lymphocytes

1980 • 85 citations

Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect

1977 • 84 citations

Trophoblast transferrin and transferrin receptors in the host–parasite relationship of human pregnancy

1979 • 81 citations

Nutritional deficiency and susceptibility to infection.

1979 • 81 citations

Influence of Temperature on the Biosynthesis of Iron Transport Compounds by Salmonella typhimurium

1972 • 79 citations

Hydroxamate-mediated transport of iron controlled by ColV plasmids

1980 • 78 citations

Intramuscular iron-dextran and susceptibility of neonates to bacterial infections. In vitro studies.

1977 • 77 citations

Bcg in Tumor Immunotherapy

1978 • 76 citations

Suggested models of ecotaxopathy in lymphoreticular malignancy. A role for iron-binding proteins in the control of lymphoid cell migration.

1978 • 75 citations

Isolation and characterization of a siderophore-like growth factor from mutants of SV40-transformed cells adapted to picolinic acid

1978 • 74 citations

Trace metal levels in cancer of the breast.

1976 • 71 citations

Iron, Zinc, Free Radicals and Oxygen in Tissue Disorders and Cancer Control

1977 • 66 citations

Hyperthermia and Local Anesthetics: Potentiation of Survival of Tumor-Bearing Mice

1979 • 63 citations

Increased resistance of iron-deficient mice to salmonella infection

1977 • 63 citations

Growth‐modulating tripeptide (glycylhistidyllysine): Associaton with copper and iron in plasma, and stimulation of adhesiveness and growth of hepatoma cells in culture by tripeptide‐metal ion complexes

1980 • 60 citations

Generalized infection with Yersinia enterocolitica and the role of iron.

1979 • 60 citations

Secondary metabolism: Regulation by phosphate and trace elements

1978 • 59 citations

The resistance of spontaneous mouse hepatocellular neoplasms to iron accumulation during rapid iron loading by parenteral administration and their transplantability.

1979 • 59 citations

Storage iron regulation.

1977 • 55 citations

8-Hydroxyquinoline: Chronic toxicity and inhibitory effect on the carcinogenicity of N-2-fluorenylacetamide

1971 • 53 citations

Intramuscular injections of iron compounds and oncogenesis in man

1978 • 52 citations

Sarcoma after intramuscular iron injection.

1976 • 50 citations

A biochemical approach to the staging of human breast cancer

1977 • 48 citations

Serum iron levels and response to hepatitis B virus

1979 • 47 citations

Regulation of expression of a human lymphoid cell surface marker by iron

1980 • 46 citations

Leukocytic endogenous mediator.

1978 • 45 citations

The Carcinogenic Action of Complex Iron Preparations

1961 • 45 citations

The Effect of Desferoxamine on Fibroblasts and Collagen Formation in Cell Cultures

1979 • 40 citations

Low molecular weight iron-binding factor from mammalian tissue that potentiates bacterial growth.

1980 • 39 citations

Some further information about the abnormal membrane glycoprotein associated with malignancy

1978 • 39 citations

Lymphoid cell positioning: a new proposal for the mechanism of control of lymphoid cell migration.

1978 • 38 citations

Inhibition of E-rosette formation by two iron salts

1978 • 37 citations

The Effects of Hyperthermia in Animal Tumour Systems

1977 • 37 citations

Carcinogenic and Cocarcinogenic Effects of Inhaled Synthetic Smog and Ferric Oxide Particles2

1975 • 36 citations

Multifractionated hyperthermia treatment of malignant and normal tissue in vivo.

1980 • 36 citations

Tissue changes following injection of iron‐dextran complex

1961 • 35 citations

Iron Metabolism in Hodgkin's Disease

1972 • 35 citations

Iron Binding Proteins in Selected Human Peripheral Blood Cell Sets: Immunofluorescence

1980 • 34 citations

The growth stimulation of SV3T3 cells by transferrin and its dependence on biotin

1979 • 34 citations

Biochemical Aspects of Heat Sensitivity of Tumour Cells

1977 • 33 citations

Iron overloading phenomena in animals

1960 • 33 citations

Temperature: A Critical Factor Determining Localization and Natural History of Infectious, Metabolic, and Immunological Diseases

1980 • 33 citations

Intramuscular iron and local oncogenesis.

1977 • 29 citations

Spontaneous pyrogen production by mouse histiocytic and myelomonocytic tumor cell lines in vitro.

1978 • 27 citations

Mechanism of placental iron transfer in the rat

1972 • 25 citations

The mutagenic activity of ferrous sulfate for Salmonella typhimurium

1976 • 24 citations

The Cancer Pattern in African Gold Miners

1971 • 24 citations

Sarcoma Induction by Iron-carbohydrate Complexes

1962 • 23 citations

Content of some trace elements in sarcoma M-1 DNA in dynamics of malignant growth.

1974 • 23 citations

Factors affecting the susceptibility of staphylococci to killing by the cationic proteins from rabbit polymorphonuclear leucocytes: the effects of alteration of cellular energetics and of various iron compounds.

1976 • 21 citations

Some systemic effects of toxohormone.

1959 • 20 citations

The Mechanism of Endotoxin‐Induced Hypoferraemia

1978 • 20 citations

Amino acid transport in normal and Rous sarcoma virus‐transformed chicken embryo fibroblasts

1979 • 18 citations

Effects of Plasma From Pregnant Women on Iron Absorption by the Rat

1969 • 18 citations

Cancer incidence and exposure to iron oxide dust.

1979 • 18 citations

Implications of reiterative DNA—Metal ion complexes in the induction and development of neoplastic cells

1979 • 17 citations

The Effects of Iron Deficiency and the Quality and Quantity of Fat on Chemically Induced Cancer

1978 • 17 citations

Correction

1978 • 14 citations

Iron negative foci and nodules in safrole-exposed mouse liver made siderotic by iron-dextran injection

1979 • 13 citations

Radioiron incorporation by a transplantable lymphoid tumor.

1973 • 13 citations

Iron‐dextran induction of distant tumours in mice

1968 • 13 citations

New dimensions in the biology of cancer

1980 • 13 citations

Early development of injection-site sarcomas in rats: a study of tumours induced by iron-dextran.

1969 • 13 citations

Electron paramagnetic resonance investigation of high‐spin iron (III) in cancer

1978 • 11 citations

Siderosis of lymph nodes in patients with Hodgkin's disease

1976 • 11 citations

Systemic salmonellosis: a sequela of sideremia.

1972 • 11 citations

Oncological Study in Rats of Ferastral®, an Iron‐poly‐(sorbitol‐gluconic acid) complex, after Intramuscular Administration

1977 • 10 citations

Iron and Copper Metabolism in Cancer, as Exemplified by Changes in Ferritin and Ceruloplasmin in Rats with Transplantable Tumors

1978 • 10 citations

Hemochromatosis: Course and Treatment

1976 • 10 citations

Microbial iron chelates with iron donor properties in hemoglobin-synthesizing cells.

1976 • 9 citations

Tissue damage in haemochromatosis: an analysis of the roles of iron and alcoholism.

1970 • 9 citations

Spleen Cell Populations in Hodgkin’s Disease

1979 • 7 citations

Immunotherapeutic effectiveness of BCG inactivated by various modalities

1980 • 7 citations

Iron homeostasis in plasmacytoma-bearing mice.

1976 • 6 citations

Sporulation competence in Aspergillus Nidulans: A role for iron in development

1978 • 6 citations

Actions of Hyperthermia on Tumor Cells Cultured in vitro

1977 • 5 citations

[Should the lung cancer of iron-miners in Lorraine be considered an occupational disease? (author's transl)].

1979 • 2 citations

The serum iron content in malignant and non-malignant diseases.

1967 • 1 citations