Effect of the different dimeric forms of the platelet‐derived growth factor on cellular responses in mouse Swiss 3T3 fibroblasts

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF

1988 • 603 citations

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

1984 • 520 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains

1986 • 418 citations

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor.

1984 • 376 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1988 • 317 citations

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.

1988 • 314 citations

A glioma-derived PDGF a chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets

1988 • 264 citations

Purification and properties of porcine platelet-derived growth factor.

1984 • 260 citations

Detection of phosphotyrosine-containing proteins in the detergent-insoluble fraction of RSV-transformed fibroblasts by azobenzene phosphonate antibodies.

1984 • 147 citations

Temporal relationship between inositol polyphosphate formation and increases in cytosolic Ca2+ in quiescent 3T3 cells stimulated by platelet-derived growth factor, bombesin and vasopressin.

1988 • 125 citations

[58] Purification of human platelet-derived growth factor

1985 • 106 citations

Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts.

1988 • 102 citations

A Common PDGF rEceptor Is Activated by Homodimeric A and B Forms of PDGF

1988 • 85 citations

Bombesin and platelet-derived growth factor stimulate formation of inositol phosphates and Ca2+ mobilization in Swiss 3T3 cells by different mechanisms

1989 • 52 citations

In vivo phosphorylation and dephosphorylation of the platelet-derived growth factor receptor studied by immunoblot analysis with phosphotyrosine antibodies

1986 • 52 citations

Kinetics and regulation of the tyrosine phosphorylation of epidermal growth factor receptor in intact A431 cells.

1988 • 51 citations

PDGF-induced receptor phosphorylation and phosphoinositide hydrolysis are unaffected by protein kinase C activation in mouse Swiss 3T3 and human skin fibroblasts

1986 • 48 citations

Dissociation of the ligand and dephosphorylation of the platelet‐derived growth factor receptor

1988 • 14 citations

Receptor Phosphorylation

2018 • 8 citations