Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

2001 • 4,399 citations

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Neuronal Calcium Signaling

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Function and Regulation of CREB Family Transcription Factors in the Nervous System

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Long-Term Potentiation and Memory

2004 • 1,888 citations

MAPK cascade signalling and synaptic plasticity

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The many faces of CREB

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Activation of Mitogen-activated Protein Kinase by H2O2

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Calibrated functional MRI: Mapping the dynamics of oxidative metabolism

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Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

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The Yin and Yang of NMDA receptor signalling

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Regulation of transcription factors by neuronal activity

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Purified ryanodine receptor from skeletal muscle sarcoplasmic reticulum is the Ca2+-permeable pore of the calcium release channel.

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Activity-dependent CREB phosphorylation: Convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway

2001 • 466 citations

Single Synaptic Events Evoke NMDA Receptor–Mediated Release of Calcium from Internal Stores in Hippocampal Dendritic Spines

1999 • 437 citations

The Skeletal Muscle Calcium Release Channel

2000 • 429 citations

Reactive oxygen species and synaptic plasticity in the aging hippocampus

2004 • 406 citations

Cellular Mechanisms Regulating Activity-Dependent Release of Native Brain-Derived Neurotrophic Factor from Hippocampal Neurons

2002 • 400 citations

Integration of calcium and RAS signalling

2002 • 375 citations

Signaling from synapse to nucleus: the logic behind the mechanisms

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S-Glutathiolation of Ras Mediates Redox-sensitive Signaling by Angiotensin II in Vascular Smooth Muscle Cells

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Molecular and cellular cognitive studies of the role of synaptic plasticity in memory

2002 • 280 citations

Control of Recruitment and Transcription-Activating Function of CBP Determines Gene Regulation by NMDA Receptors and L-Type Calcium Channels

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NMDA Receptor-Mediated Subthreshold Ca²⁺Signals in Spines of Hippocampal Neurons

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Stores Not Just for Storage

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Impairment of Long-term Potentiation and Associative Memory in Mice That Overexpress Extracellular Superoxide Dismutase

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NADPH oxidase immunoreactivity in the mouse brain

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Synaptic localization of a functional NADPH oxidase in the mouse hippocampus

2005 • 207 citations

Hydrogen peroxide‐mediated phosphorylation of ERK1/2, Akt/PKB and JNK in cortical neurones: dependence on Ca²⁺ and PI3‐kinase

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Sulfhydryl Oxidation Modifies the Calcium Dependence of Ryanodine-Sensitive Calcium Channels of Excitable Cells

1998 • 204 citations

Oxidative stress and ageing: is ageing a cysteine deficiency syndrome?

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Release of calcium from stores alters the morphology of dendritic spines in cultured hippocampal neurons

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Hydrogen Peroxide Modulation of Synaptic Plasticity

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Deletion of the ryanodine receptor type 3 (RyR3) impairs forms of synaptic plasticity and spatial learning

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Early and Simultaneous Emergence of Multiple Hippocampal Biomarkers of Aging Is Mediated by Ca²⁺-Induced Ca²⁺Release

2006 • 175 citations

Facilitation of NMDAR-Independent LTP and Spatial Learning in Mutant Mice Lacking Ryanodine Receptor Type 3

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Cell-Permeable Scavengers of Superoxide Prevent Long-Term Potentiation in Hippocampal Area CA1

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Excitation-Transcription Coupling: Signaling by Ion Channels to the Nucleus

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Ryanodine Receptors Contribute to cGMP-Induced Late-Phase LTP and CREB Phosphorylation in the Hippocampus

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A Similar DNA-binding Motif in NFAT Family Proteins and the Rel Homology Region

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NADPH oxidase is required for NMDA receptor‐dependent activation of ERK in hippocampal area CA1

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Hydrogen Peroxide As a Diffusible Signal Molecule in Synaptic Plasticity

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Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle

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Redox Regulation of cAMP-responsive Element-binding Protein and Induction of Manganous Superoxide Dismutase in Nerve Growth Factor-dependent Cell Survival

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Nitric oxide synthase-independent long-term potentiation in area CA1 of hippocampus

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S-Glutathionylation Decreases Mg2+ Inhibition and S-Nitrosylation Enhances Ca2+ Activation of RyR1 Channels

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Reactive oxygen species and nitric oxide mediate plasticity of neuronal calcium signaling

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Stimulation of p42 and p44 Mitogen‐Activated Protein Kinases by Reactive Oxygen Species and Nitric Oxide in Hippocampus

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Paradoxical Actions of Hydrogen Peroxide on Long-Term Potentiation in Transgenic Superoxide Dismutase-1 Mice

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The Ryanodine Receptors Ca2 + Release Channels: Cellular Redox Sensors?

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Ebselen attenuates oxidative stress‐induced apoptosis via the inhibition of the c‐Jun N‐terminal kinase and activator protein‐1 signalling pathway in PC12 cells

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Spatial learning induced changes in expression of the ryanodine type II receptor in the rat hippocampus

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Oxidative stress differentially modulates phosphorylation of ERK, p38 and CREB induced by NGF or EGF in PC12 cells☆

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Redox sensing properties of the Ryanodine receptor complex

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Postsynaptic Modulation of AMPA Receptor-Mediated Synaptic Responses and LTP by the Type 3 Ryanodine Receptor

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CREB Signaling-Timing Is Everything

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Calcium-dependent mitochondrial superoxide modulates nuclear CREB phosphorylation in hippocampal neurons

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Endoplasmic reticulum calcium signaling in nerve cells

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Ras Regulation by Reactive Oxygen and Nitrogen Species

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Transcriptional profiling of brain‐derived‐neurotrophic factor‐induced neuronal plasticity: A novel role for nociceptin in hippocampal neurite outgrowth

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Signal transduction and gene expression regulated by calcium release from internal stores in excitable cells

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Progressive iron accumulation induces a biphasic change in the glutathione content of neuroblastoma cells

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SH oxidation coordinates subunits of rat brain ryanodine receptor channels activated by calcium and ATP

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Inhibition of Age-Induced β-Amyloid Neurotoxicity in Rat Hippocampal Cells

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Redox sensing properties of the Ryanodine receptor complex

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The BDNF Gene: Exemplifying Complexity in Ca2+-Dependent Gene Expression

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Depolarization of Skeletal Muscle Cells induces Phosphorylation of cAMP Response Element Binding Protein via Calcium and Protein Kinase Cα

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Differential modulation of NMDA‐induced calcium transients by arachidonic acid and nitric oxide in cultured hippocampal neurons

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Detection of Redox Sensor of Ryanodine Receptor Complexes

2002 • 13 citations