Aldosterone Antagonism Ameliorates Proteinuria and Nephrosclerosis Independent of Glomerular Dynamics in <i>L</i>-NAME/SHR Model

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The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

1999 • 8,588 citations

Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction

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The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

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Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats

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Mineralocorticoid Blockade Reduces Vascular Injury in Stroke-Prone Hypertensive Rats

1998 • 504 citations

Role of aldosterone in the remnant kidney model in the rat.

1996 • 473 citations

Aldosterone: A Mediator of Myocardial Necrosis and Renal Arteriopathy*

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Effectiveness of Aldosterone Blockade in Patients With Diabetic Nephropathy

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Regulation of Aldosterone Secretion

1988 • 311 citations

Role of Aldosterone in Renal Vascular Injury in Stroke-Prone Hypertensive Rats

1999 • 311 citations

Effects of the Selective Aldosterone Blocker Eplerenone Versus the Calcium Antagonist Amlodipine in Systolic Hypertension

2003 • 295 citations

Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo

2000 • 256 citations

Aldosterone escape during angiotensin-converting enzyme inhibitor therapy in chronic heart failure

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Plasma aldosterone concentrations in chronic renal disease

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Reversal of Glomerulosclerosis after High-Dose Enalapril Treatment in Subtotally Nephrectomized Rats

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The paradox of the renin-angiotensin system in chronic renal disease

1994 • 156 citations

Aldosterone as a mediator of progressive renal disease: Pathogenetic and clinical implications

2001 • 156 citations

Aldosterone: A Mediator of Myocardial Necrosis and Renal Arteriopathy

2000 • 130 citations

Antiproteinuric efficacy of eplerenone, enalapril, and eplerenone/enalapril combination therapy in diabetic hypertensives with microalbuminuria

2002 • 120 citations

Locally Activated Renin-Angiotensin System Associated with TGF-β1 as a Major Factor for Renal Injury Induced by Chronic Inhibition of Nitric Oxide Synthase in Rats

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Nitric Oxide Synthase Inhibition in Spontaneously Hypertensive Rats

1995 • 90 citations

Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift

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Effects of chronic NO synthase inhibition in rats on renin-angiotensin system and sympathetic nervous system

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Hydrostatic pressures in peritubular capillaries and tubules in the rat kidney

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Late escape from the antiproteinuric effect of ACE inhibitors in nondiabetic renal disease

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ACE Inhibition Prevents and Reverses L-NAMEExacerbated Nephrosclerosis in Spontaneously Hypertensive Rats

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Renoprotective Effects of Felodipine and/or Enalapril in Spontaneously Hypertensive Rats With and Without L-NAME

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Influence of Nitric Oxide and Angiotensin II on Renal Involvement in Hypertension

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Role of angiotensin II in tubulointerstitial injury

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Hydrochlorothiazide exacerbates nitric oxide-blockade nephrosclerosis with glomerular hypertension in spontaneously hypertensive rats

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Aldosterone: A risk factor for vascular disease

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Role of angiotensin II in glomerular injury

2001 • 53 citations

Angiotensin Type 1 Receptor Antagonism and ACE Inhibition Produce Similar Renoprotection in N ^ω -Nitro- <scp>l</scp> &gt;-Arginine Methyl Ester/Spontaneously Hypertensive Rats

2001 • 49 citations

Apoptosis and Glomerular Injury After Prolonged Nitric Oxide Synthase Inhibition in Spontaneously Hypertensive Rats

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Mechanisms of albuminuria in the chronic nitric oxide inhibition model

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Plasma Aldosterone Concentrations Are Not Related to the Degree of Angiotensin-Converting Enzyme Inhibition in Essential Hypertensive Patients.

2000 • 33 citations

NITRIC OXIDE SYNTHASE INHIBITION IN A SPONTANEOUSLY HYPERTENSIVE RAT MODEL OF DIABETIC NEPHROPATHY

1997 • 16 citations