Distinct CpG oligonucleotide sequences activate human γ δ T cells via interferon-α/-β

A Toll-like receptor recognizes bacterial DNA

2000 • 6,348 citations

CpG motifs in bacterial DNA trigger direct B-cell activation

1995 • 3,543 citations

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

1999 • 1,754 citations

Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 • 1,262 citations

Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells

1998 • 1,134 citations

γδ Cells: A Right Time and a Right Place for a Conserved Third Way of Protection

2000 • 1,107 citations

Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

1996 • 1,077 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells

2001 • 883 citations

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

1998 • 809 citations

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

2001 • 798 citations

Type I Interferons Keep Activated T Cells Alive

1999 • 769 citations

Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA.

1996 • 764 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells

1999 • 638 citations

Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells

2000 • 604 citations

Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo

2000 • 593 citations

Human Peripheral Blood Cells Differentially Recognize and Respond to Two Distinct CpG Motifs

2001 • 518 citations

Antitumor Activity of Deoxyribonucleic Acid Fraction From <italic>Mycobacterium bovis</italic> BCG. I. Isolation, Physicochemical Characterization, and Antitumor Activity<xref ref-type="fn" rid="FN2">2</xref>

1984 • 471 citations

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

1995 • 468 citations

Self-Recognition of Cd1 by γ/δ T Cells

2000 • 367 citations

Type I Interferon-mediated Stimulation of T Cells by CpG DNA

1998 • 361 citations

Bacterial CpG-DNA Triggers Activation and Maturation of Human CD11c−, CD123+ Dendritic Cells

2001 • 306 citations

Two Roads Diverged: Interferon α/β– and Interleukin 12–mediated Pathways in Promoting T Cell Interferon γ Responses during Viral Infection

1999 • 299 citations

Interferon α/β-mediated inhibition and promotion of interferon γ: STAT1 resolves a paradox

2000 • 293 citations

Distinct CpG DNA and Polyinosinic-Polycytidylic Acid Double-Stranded RNA, Respectively, Stimulate CD11c− Type 2 Dendritic Cell Precursors and CD11c+ Dendritic Cells to Produce Type I IFN

2001 • 278 citations

Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-γ production in cells from allergic individuals and inhibit IgE synthesisin vitro

1999 • 231 citations

Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2

2000 • 190 citations

CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells

1999 • 155 citations

Control of self‐reactive cytotoxic T lymphocytes expressing γδ T cell receptors by natural killer inhibitory receptors

1997 • 151 citations

Causing a commotion in the blood: immunotherapy progresses from bacteria to bacterial DNA

2000 • 131 citations

CD1-restricted T-cell responses and microbial infection

2000 • 128 citations

Control of B cell lymphoma recognition via natural killer inhibitory receptors implies a role for human Vγ9/Vδ2 T cells in tumor immunity

1997 • 120 citations

Mechanism of Action of CpG DNA

2000 • 119 citations

Oligodeoxynucleotides containing palindrome sequences with internal 5'-CpG-3' act directly on human NK and activated T cells to induce IFN-gamma production in vitro.

1999 • 115 citations

CpG‐oligodeoxynucleotides enhance T‐cell receptor‐triggered interferon‐γ production and up‐regulation of CD69 via induction of antigen‐presenting cell‐derived interferon type I and interleukin‐12

2000 • 112 citations

Oligodeoxynucleotides Containing Palindrome Sequences with Internal 5′-CpG-3′ Act Directly on Human NK and Activated T Cells to Induce IFN-γ Production In Vitro

1999 • 84 citations

Poly‐guanosine motifs costimulate antigen‐reactive CD8 T cells while bacterial CpG‐DNA affect T‐cell activation via antigen‐presenting cell‐derived cytokines

2000 • 53 citations

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40L to induce high amounts of IL-12

2001 • 6 citations