Bioaffinity therapy with antibodies and drugs bound to soluble synthetic polymers

Targeting to cells of fluorescent liposomes covalently coupled with monoclonal antibody or protein A

1980 • 374 citations

Soluble synthetic polymers as potential drug carriers

1984 • 308 citations

New Lymphocyte Antigen System ( Lna ) Controlled by the Ir Region of the Mouse H-2 Complex

1973 • 282 citations

SOME EXPERIMENTS ON THE ACTION OF ANTILYMPHOID ANTISERA

1966 • 275 citations

Polymers containing enzymatically degradable bonds, 8. Degradation of oligopeptide sequences in N‐(2‐hydroxypropyl)methacrylamide copolymers by bovine spleen cathepsin B

1983 • 259 citations

Aminolyses of monomeric and polymeric 4‐nitrophenyl esters of N‐methacryloylamino acids

1977 • 202 citations

The Preparation and Cytotoxic Properties of Antibody‐Toxin Conjugates

1982 • 199 citations

Immunotoxins: Hybrid Molecules Combining High Specificity and Potent Cytotoxicity

1982 • 181 citations

Suppression of tumour growth in mice by a drug–antibody conjugate using a novel approach to linkage

1975 • 159 citations

Polymers containing enzymatically degradable bonds, 1. Chymotrypsin catalyzed hydrolysis of p‐nitroanilides of phenylalanine and tyrosine attached to side‐chains of copolymers of N‐(2‐hydroxypropyl)methacrylamide

1981 • 141 citations

Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers

1985 • 138 citations

Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues

1983 • 128 citations

Monoclonal Antibody‐Ricin or Ricin A Chain Hybrids: Kinetic Analysis of Cell Killing for Tumor Therapy

1982 • 109 citations

Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases

1982 • 102 citations

Biological properties of targetable poly[N-(2-hydroxypropyl)-methacrylamide]-antibody conjugates

1985 • 99 citations

LIPOSOMES IN THERAPEUTIC AND PREVENTIVE MEDICINE: THE DEVELOPMENT OF THE DRUG‐CARRIER CONCEPT

1978 • 92 citations

Neoplastic B Cells as Targets for Antibody‐Ricin A Chain Immunotoxins

1982 • 85 citations

Recent advances in drug delivery systems

1985 • 78 citations

Immunogenicity of N-(2-hydroxypropyl)-methacrylamide copolymers—Potential hapten or drug carriers

1983 • 74 citations

A hybrid protein containing the toxic subunit of ricin and the cell-specific subunit of human chorionic gonadotropin. II. Biologic properties.

1979 • 69 citations

Estimation of the inductive phase of antibody formation by plaque technique

1964 • 68 citations

Polymers containing enzymatically degradable bonds V. Hydrophilic polymers degradable by papain

1980 • 65 citations

Artificial hybrid protein containing a toxic protein fragment and a cell membrane receptor-binding moiety in a disulfide conjugate. I. Synthesis of diphtheria toxin fragment A-S-S-human placental lactogen with methyl-5-bromovalerimidate.

1977 • 64 citations

Immunogenicity of N-(2-hydroxypropyl) methacrylamide copolymers

1985 • 61 citations

Effect of the chemical structure of N- (2- hydroxypropyl) methacrylajnide copolymers on their ability to induce antibody formation in inbred strains of mice

1984 • 60 citations

Antibody Mediated Delivery of Toxic Molecules to Antigen Bearing Target Cells

1982 • 59 citations

Polymers containing enzymatically degradable bonds, 3. Poly[N‐(2‐hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by trypsin

1981 • 58 citations

ESTABLISHMENT AND CHARACTERIZATION OF PERMANENT MURINE HYBRIDOMAS SECRETING MONOCLONAL ANTI‐THY‐1 ANTIBODIES *

1980 • 41 citations

Membrane transport of macromolecules: New carrier functions of proteins and poly(amino acids)

1978 • 30 citations

ENHANCEMENT OF CHEMOTHERAPEUTIC EFFECT BY ENTRAPPING 1‐β‐D‐ARABINOFURANOSYLCYTOSINE IN LIPID VESICLES AND ITS MODE OF ACTION *

1978 • 28 citations

Methods of targeting N-(2-hydroxypropyl) methacrylamide copolymers to particular cell types

1985 • 26 citations