GM-CSF-secreting melanoma vaccines

The Hallmarks of Cancer

2000 • 27,569 citations

Dendritic cells and the control of immunity

1998 • 14,345 citations

Immunobiology of Dendritic Cells

2000 • 6,653 citations

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

1997 • 2,370 citations

The Basic Science of Gene Therapy

1993 • 1,767 citations

The Central Role of CD4+ T Cells in the Antitumor Immune Response

1998 • 1,332 citations

MOUSE CD1-SPECIFIC NK1 T CELLS: Development, Specificity, and Function

1997 • 1,326 citations

Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV Melanoma

1999 • 1,260 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

Model Predicting Survival in Stage I Melanoma Based on Tumor Progression

1989 • 1,235 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma

1996 • 1,110 citations

Human neoplasms elicit multiple specific immune responses in the autologous host.

1995 • 1,097 citations

Complexities of CD28/B7: CTLA-4 Costimulatory Pathways in Autoimmunity and Transplantation

2001 • 1,032 citations

Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

1999 • 1,006 citations

Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation

1999 • 1,000 citations

CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy

2001 • 964 citations

Human tumor antigens recognized by T lymphocytes.

1996 • 860 citations

The Emerging Role of CTLA-4 as an Immune Attenuator

1997 • 637 citations

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

1998 • 586 citations

Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow.

1993 • 428 citations

Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses

2000 • 407 citations

Characterization of human colon cancer antigens recognized by autologous antibodies

1998 • 335 citations

Elucidating the Autoimmune and Antitumor Effector Mechanisms of a Treatment Based on Cytotoxic T Lymphocyte Antigen-4 Blockade in Combination with a B16 Melanoma Vaccine

2001 • 307 citations

NKT cells — conductors of tumor immunity?

2002 • 289 citations

Experimental and Clinical Studies of Cytokine Gene-Modified Tumor Cells

1994 • 259 citations

A Monocyte Conditioned Medium Is More Effective Than Defined Cytokines in Mediating the Terminal Maturation of Human Dendritic Cells

1997 • 256 citations

CD4⁺T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA DP4 allele: Association with NY-ESO-1 antibody production

2001 • 199 citations

Antigens recognized by autologous antibody in patients with renal-cell carcinoma

1999 • 170 citations

Gene Transfer as Cancer Therapy

1995 • 142 citations

A novel accessory subunit for vacuolar H(+)-ATPase from chromaffin granules.

1994 • 129 citations

Cytokine-secreting tumor cell vaccines

2000 • 119 citations

Induction of Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) <u>Restricts</u> Clonal Expansion of Helper T Cells

2001 • 105 citations

Helper strategy in tumor immunology: Expansion of helper lymphocytes and utilization of helper lymphokines for experimental and clinical immunotherapy

1988 • 69 citations

ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction

2002 • 49 citations

Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient.

1990 • 44 citations

Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands

1999 • 40 citations