Cyclin-Dependent Kinase 5 Phosphorylates the N-Terminal Domain of the Postsynaptic Density Protein PSD-95 in Neurons

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

1993 • 2,272 citations

Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95

1995 • 1,861 citations

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

1996 • 1,589 citations

PSD-95 Involvement in Maturation of Excitatory Synapses

2000 • 1,238 citations

The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein

1992 • 1,180 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

1983 • 1,162 citations

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

1998 • 1,147 citations

A decade of CDK5

2001 • 1,027 citations

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

1995 • 994 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

Signal-Processing Machines at the Postsynaptic Density

2000 • 792 citations

Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases

1996 • 735 citations

Binding of Neuroligins to PSD-95

1997 • 731 citations

SynGAP: a Synaptic RasGAP that Associates with the PSD-95/SAP90 Protein Family

1998 • 617 citations

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.

1996 • 592 citations

A Synaptic Ras-GTPase Activating Protein (p135 SynGAP) Inhibited by CaM Kinase II

1998 • 578 citations

A Structural Basis for Substrate Specificities of Protein Ser/Thr Kinases: Primary Sequence Preference of Casein Kinases I and II, NIMA, Phosphorylase Kinase, Calmodulin-Dependent Kinase II, CDK5, and Erk1

1996 • 555 citations

Heteromultimerization and NMDA Receptor-Clustering Activity of Chapsyn-110, a Member of the PSD-95 Family of Proteins

1996 • 539 citations

PDZ domains in synapse assembly and signalling

2000 • 525 citations

NUDEL Is a Novel Cdk5 Substrate that Associates with LIS1 and Cytoplasmic Dynein

2000 • 482 citations

PDZ Proteins Organize Synaptic Signaling Pathways

1998 • 474 citations

SAP102, a Novel Postsynaptic Protein That Interacts with NMDA Receptor Complexes In Vivo

1996 • 422 citations

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

1998 • 403 citations

Identification of Proteins in the Postsynaptic Density Fraction by Mass Spectrometry

2000 • 399 citations

Heterogeneity in the Molecular Composition of Excitatory Postsynaptic Sites during Development of Hippocampal Neurons in Culture

1998 • 396 citations

Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein

1995 • 388 citations

p35 and p39 Are Essential for Cyclin-Dependent Kinase 5 Function during Neurodevelopment

2001 • 379 citations

Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1.

1994 • 365 citations

Ligand-Gated Ion Channel Interactions with Cytoskeletal and Signaling Proteins

2000 • 352 citations

Synaptic Targeting of the Postsynaptic Density Protein PSD-95 Mediated by Lipid and Protein Motifs

1999 • 327 citations

Cloning and Characterization of Postsynaptic Density 93, a Nitric Oxide Synthase Interacting Protein

1996 • 327 citations

The dynamic role of palmitoylation in signal transduction

1995 • 315 citations

Rapid formation and remodeling of postsynaptic densities in developing dendrites

2001 • 298 citations

N-Terminal Palmitoylation of PSD-95 Regulates Association with Cell Membranes and Interaction with K+ Channel Kv1.4

1998 • 292 citations

Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities

1991 • 272 citations

Dual Palmitoylation of Psd-95 Mediates Its Vesiculotubular Sorting, Postsynaptic Targeting, and Ion Channel Clustering

2000 • 272 citations

Regulation of DLG Localization at Synapses by CaMKII-Dependent Phosphorylation

1999 • 270 citations

Reversible palmitoylation of signaling proteins

1997 • 256 citations

Regulation of NMDA receptors by cyclin-dependent kinase-5

2001 • 255 citations

Interaction of the Postsynaptic Density-95/Guanylate Kinase Domain-Associated Protein Complex with a Light Chain of Myosin-V and Dynein

2000 • 250 citations

Continual remodeling of postsynaptic density and its regulation by synaptic activity

1999 • 244 citations

Disulfide-Linked Head-to-Head Multimerization in the Mechanism of Ion Channel Clustering by PSD-95

1997 • 207 citations

Differential K + Channel Clustering Activity of PSD-95 and SAP97, Two Related Membrane-associated Putative Guanylate Kinases

1996 • 146 citations

Molecular heterogeneity of central synapses: afferent and target regulation

2001 • 143 citations

Substrate specificity characterization of a cdc2-like protein kinase purified from bovine brain.

1993 • 127 citations

Postsynaptic Targeting of Alternative Postsynaptic Density-95 Isoforms by Distinct Mechanisms

2002 • 126 citations

Development of neuron–neuron synapses

2000 • 103 citations

Assembly and plasticity of the glutamatergic postsynaptic specialization

2003 • 103 citations

Requirement of N-terminal Cysteines of PSD-95 for PSD-95 Multimerization and Ternary Complex Formation, but Not for Binding to Potassium Channel Kv1.4

1999 • 83 citations

Synaptic localization of p39, a neuronal activator of cdk5

2000 • 62 citations