Presence of a New Conserved Domain in CART1, a Novel Member of the Tumor Necrosis Factor Receptor-associated Protein Family, Which Is Expressed in Breast Carcinoma

Basic local alignment search tool

1990 • 87,358 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Progressive sequence alignment as a prerequisitetto correct phylogenetic trees

1987 • 1,899 citations

Zinc coordination, function, and structure of zinc enzymes and other proteins

1990 • 1,731 citations

Molecular themes in oncogenesis

1991 • 1,663 citations

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1994 • 1,043 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1995 • 990 citations

Breast cancer screening with mammography: overview of Swedish randomised trials

1993 • 981 citations

c-erbB-2 Expression and Response to Adjuvant Therapy in Women with Node-Positive Early Breast Cancer

1994 • 981 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1995 • 454 citations

The RING Finger

1993 • 417 citations

THE BIOCHEMISTRY OF 3′-END CLEAVAGE AND POLYADENYLATION OF MESSENGER RNA PRECURSORS

1992 • 387 citations

Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins

1989 • 358 citations

A novel RING finger protein interacts with the cytoplasmic domain of CD40.

1994 • 345 citations

The LIM domain: a new structural motif found in zinc-finger-like proteins

1994 • 327 citations

Identification and preliminary characterization of a protein motif related to the zinc finger.

1993 • 327 citations

The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML.

1995 • 324 citations

Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen.

1991 • 322 citations

Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2.

1987 • 279 citations

Cytokine receptors and signal transduction

1992 • 269 citations

Identification of Four Novel Human Genes Amplified and Overexpressed in Breast Carcinoma and Localized to the q11-q21.3 Region of Chromosome 17

1995 • 248 citations

Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2

1991 • 242 citations

How Big Is the Universe of Exons?

1990 • 228 citations

rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.

1988 • 150 citations

TheSaccharomyces cerevisiae RAD18gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequence

1988 • 147 citations

Plasmid and bacteriophage vectors for excision of intact inserts

1987 • 127 citations

Expression of novel DNA-binding protein with zinc finger structure in various tumor cells.

1990 • 120 citations

The cloning and characterization of a maternally expressed novel zinc finger nuclear phosphoprotein (xnf7) in Xenopus laevis

1991 • 103 citations

The p53-associated protein MDM2 contains a newly characterized zinc-binding domain called the RING finger

1994 • 92 citations

Expression of tumour necrosis factor α and its receptors in carcinoma of the breast

1994 • 75 citations

Why do cancer cells metastasize into particular organs?

1992 • 71 citations

Clinical implications of metastatic process

1992 • 63 citations

Zinc finger diversity

1994 • 43 citations

The biology of breast cancer

1994 • 22 citations

The mouseMel-18“RING-finger” gene: genomic organization, promoter analysis and chromosomal assignment

1993 • 13 citations