IFNα activates dormant haematopoietic stem cells in vivo
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Abstract
References (31)
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 • 5,932 citations
HOW CELLS RESPOND TO INTERFERONS
1998 • 3,937 citations
SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells
2005 • 3,056 citations
Functional Role of Type I and Type II Interferons in Antiviral Defense
1994 • 2,437 citations
Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell
1996 • 2,160 citations
Inducible Gene Targeting in Mice
1995 • 1,897 citations
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
2008 • 1,753 citations
Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease
1996 • 1,560 citations
Bone-marrow haematopoietic-stem-cell niches
2006 • 1,332 citations
Hematopoietic Stem Cell Quiescence Maintained by p21 cip1/waf1
2000 • 1,326 citations
Interferons at age 50: past, current and future impact on biomedicine
2007 • 1,102 citations
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
2008 • 818 citations
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
2004 • 784 citations
Upregulation of Flt3 Expression within the Bone Marrow Lin−Sca1+c-kit+ Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity
2001 • 691 citations
Innate Recognition of Viruses
2007 • 671 citations
Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years
2006 • 539 citations
Complex Modulation of Cell Type-Specific Signaling in Response to Type I Interferons
2006 • 500 citations
Chronic myeloid leukaemia
2007 • 490 citations
Concise Review: Stem Cell Antigen-1: Expression, Function, and Enigma
2007 • 381 citations
Phenotypic and Functional Changes Induced at the Clonal Level in Hematopoietic Stem Cells After 5-Fluorouracil Treatment
1997 • 280 citations
5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation.
1990 • 247 citations
Dormant and Self‐Renewing Hematopoietic Stem Cells and Their Niches
2007 • 225 citations
Mechanisms of Disease: cancer stem cells—targeting the evil twin
2008 • 194 citations
Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A–null mice
2002 • 186 citations
Targeted CML therapy: controlling drug resistance, seeking cure
2005 • 179 citations
The role of interferon-alpha in the treatment of chronic myeloid leukemia
2007 • 77 citations
Prostaglandin A2-mediated Stabilization of p21 mRNA through an ERK-dependent Pathway Requiring the RNA-binding Protein HuR
2004 • 77 citations
Celebrating the New
2008 • 75 citations
Therapeutic targets in chronic myeloid leukaemia
2007 • 38 citations
First-Line management of CML: a state of the art review.
2008 • 13 citations
Optimal initial therapy for patients with newly diagnosed chronic myeloid leukemia in chronic phase
2007 • 4 citations