Back to search

IFNα activates dormant haematopoietic stem cells in vivo

Data up to Jan 2025

Published2009
Citations1,230
References31

Total Citations Per Year

Abstract

References (31)

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

HOW CELLS RESPOND TO INTERFERONS

1998 • 3,937 citations

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

2005 • 3,056 citations

Functional Role of Type I and Type II Interferons in Antiviral Defense

1994 • 2,437 citations

Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell

1996 • 2,160 citations

Inducible Gene Targeting in Mice

1995 • 1,897 citations

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

2008 • 1,753 citations

Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

1996 • 1,560 citations

Bone-marrow haematopoietic-stem-cell niches

2006 • 1,332 citations

Hematopoietic Stem Cell Quiescence Maintained by p21 cip1/waf1

2000 • 1,326 citations

Interferons at age 50: past, current and future impact on biomedicine

2007 • 1,102 citations

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

2008 • 818 citations

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

2004 • 784 citations

Upregulation of Flt3 Expression within the Bone Marrow Lin−Sca1+c-kit+ Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity

2001 • 691 citations

Innate Recognition of Viruses

2007 • 671 citations

Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years

2006 • 539 citations

Complex Modulation of Cell Type-Specific Signaling in Response to Type I Interferons

2006 • 500 citations

Chronic myeloid leukaemia

2007 • 490 citations

Concise Review: Stem Cell Antigen-1: Expression, Function, and Enigma

2007 • 381 citations

Phenotypic and Functional Changes Induced at the Clonal Level in Hematopoietic Stem Cells After 5-Fluorouracil Treatment

1997 • 280 citations

5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation.

1990 • 247 citations

Dormant and Self‐Renewing Hematopoietic Stem Cells and Their Niches

2007 • 225 citations

Mechanisms of Disease: cancer stem cells—targeting the evil twin

2008 • 194 citations

Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A–null mice

2002 • 186 citations

Targeted CML therapy: controlling drug resistance, seeking cure

2005 • 179 citations

The role of interferon-alpha in the treatment of chronic myeloid leukemia

2007 • 77 citations

Prostaglandin A2-mediated Stabilization of p21 mRNA through an ERK-dependent Pathway Requiring the RNA-binding Protein HuR

2004 • 77 citations

Celebrating the New

2008 • 75 citations

Therapeutic targets in chronic myeloid leukaemia

2007 • 38 citations

First-Line management of CML: a state of the art review.

2008 • 13 citations

Optimal initial therapy for patients with newly diagnosed chronic myeloid leukemia in chronic phase

2007 • 4 citations

Cited By (0)

Loading...
IFNα activates dormant haematopoietic stem cells in vivo (2009) – Nature | Metascience Observatory Explorer