Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

2003 • 3,114 citations

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

2001 • 2,534 citations

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

2002 • 2,081 citations

The role of the novel adipocyte-derived hormone adiponectin in human disease

2003 • 1,097 citations

Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis

2003 • 922 citations

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

2001 • 896 citations

Adiponectin: action, regulation and association to insulin sensitivity

2005 • 631 citations

Mice Lacking Adiponectin Show Decreased Hepatic Insulin Sensitivity and Reduced Responsiveness to Peroxisome Proliferator-activated Receptor γ Agonists

2005 • 621 citations

Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity

2004 • 543 citations

A Transgenic Mouse with a Deletion in the Collagenous Domain of Adiponectin Displays Elevated Circulating Adiponectin and Improved Insulin Sensitivity

2003 • 533 citations

Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

2003 • 481 citations

Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice

2000 • 357 citations

Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARα, PPARγ, and LXR

2003 • 262 citations

Effects of Diet and Genetic Background on Sterol Regulatory Element-Binding Protein-1c, Stearoyl-CoA Desaturase 1, and the Development of the Metabolic Syndrome

2005 • 232 citations

Adiponectin and its role in the obesity-induced insulin resistance and related complications.

2004 • 222 citations

Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase

2002 • 197 citations

Adiponectin and its role in the obesity-induced insulin resistance and related complications.

2004 • 183 citations

Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1

2004 • 174 citations

Serine Phosphorylation Proximal to Its Phosphotyrosine Binding Domain Inhibits Insulin Receptor Substrate 1 Function and Promotes Insulin Resistance

2004 • 124 citations

Expression of Adiponectin Receptor mRNA in Human Skeletal Muscle Cells Is Related to In Vivo Parameters of Glucose and Lipid Metabolism

2004 • 122 citations

Insulin Regulation of Fatty Acid Synthase Gene Transcription: Roles of USF and SREBP‐1c

2004 • 113 citations

Adiponectin Receptor 1 Gene (ADIPOR1) as a Candidate for Type 2 Diabetes and Insulin Resistance

2004 • 99 citations

Genetic Variation in Adiponectin Receptor 1 and Adiponectin Receptor 2 Is Associated With Type 2 Diabetes in the Old Order Amish

2005 • 98 citations

Regulation of adiponectin receptor gene expression in diabetic mice

2004 • 98 citations

Adiponectin downregulates its own production and the expression of its AdipoR2 receptor in transgenic mice

2006 • 80 citations

Adiponectin Is Functionally Active in Human Islets but Does Not Affect Insulin Secretory Function or β-Cell Lipoapoptosis

2005 • 77 citations

Genetic Analysis of ADIPOR1 and ADIPOR2 Candidate Polymorphisms for Type 2 Diabetes in the Caucasian Population

2006 • 74 citations

Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy

2005 • 72 citations

Potential Role of Acyl-Coenzyme A:Cholesterol Transferase (ACAT) Inhibitors as Hypolipidemic and Antiatherosclerosis Drugs

2005 • 71 citations

A Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with a Unique in Vitro Profile and Potent Glucose and Lipid Effects in Rodent Models of Type 2 Diabetes and Dyslipidemia

2005 • 65 citations

Obesity and lipids

2005 • 45 citations

Genetic variants of adiponectin receptor 2 are associated with increased adiponectin levels and decreased triglyceride/VLDL levels in patients with metabolic syndrome.

2006 • 32 citations