Adiponectin downregulates its own production and the expression of its AdipoR2 receptor in transgenic mice

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

2001 • 4,874 citations

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

1999 • 4,825 citations

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

2002 • 4,335 citations

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

1995 • 3,159 citations

Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients

2000 • 3,142 citations

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

2003 • 3,114 citations

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

2001 • 2,534 citations

Novel Modulator for Endothelial Adhesion Molecules

1999 • 2,168 citations

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

2002 • 2,081 citations

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

2001 • 1,903 citations

PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

2001 • 1,659 citations

Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

2000 • 1,438 citations

Tumor Necrosis Factor α: A Key Component of the Obesity-Diabetes Link

1994 • 1,302 citations

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

2003 • 1,155 citations

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

2003 • 1,056 citations

Adiponectin Reduces Atherosclerosis in Apolipoprotein E-Deficient Mice

2002 • 1,028 citations

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

2002 • 969 citations

Uncoupling of Obesity from Insulin Resistance Through a Targeted Mutation in aP2 , the Adipocyte Fatty Acid Binding Protein

1996 • 900 citations

Adiponectin acts in the brain to decrease body weight

2004 • 797 citations

Minireview: Adiposity, Inflammation, and Atherogenesis

2003 • 773 citations

Update on Adipocyte Hormones

2004 • 633 citations

Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation

2005 • 626 citations

Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity

2004 • 543 citations

A Transgenic Mouse with a Deletion in the Collagenous Domain of Adiponectin Displays Elevated Circulating Adiponectin and Improved Insulin Sensitivity

2003 • 533 citations

Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-α

2003 • 517 citations

Involvement of AMP-Activated Protein Kinase in Glucose Uptake Stimulated by the Globular Domain of Adiponectin in Primary Rat Adipocytes

2003 • 446 citations

Tissue distribution of the AMP‐activated protein kinase, and lack of activation by cyclic‐AMP‐dependent protein kinase, studied using a specific and sensitive peptide assay

1989 • 437 citations

Adipose tissue and adipokines: for better or worse

2004 • 381 citations

Modulation of Adipose Tissue Expression of Murine Matrix Metalloproteinases and Their Tissue Inhibitors With Obesity

2002 • 262 citations

A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo.

1990 • 217 citations

Influences of Ionomycin, Dibutyryl-cycloAMP and Tumour Necrosis Factor-alpha on Intracellular Amount and Secretion of apM1 in Differentiating Primary Human Preadipocytes

2000 • 192 citations

Peripheral, But Not Central, Administration of Adiponectin Reduces Visceral Adiposity and Upregulates the Expression of Uncoupling Protein in Agouti Yellow (Ay/a) Obese Mice

2003 • 148 citations

Pre- and post-translational negative effect of β-adrenoceptor agonists on adiponectin secretion: in vitro and in vivo studies

2002 • 144 citations

Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins

2002 • 139 citations

Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins

2002 • 121 citations

Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3‐L1 adipocytes

2004 • 105 citations

Regulation by fatty acids of angiotensinogen gene expression in preadipose cells

1997 • 83 citations

Chromosomal Localization, Expression Pattern, and Promoter Analysis of the Mouse Gene Encoding Adipocyte-Specific Secretory Protein Acrp30

2001 • 71 citations

Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: correlations with aberrant crypt foci promotion in rats.

2003 • 69 citations

Glucose Transporter in Insulin Sensitive Tissues of Lean and Obese Mice. Effect of the Thermogenic Agent BRL 26830A*

1990 • 69 citations

Leptin treatment markedly increased plasma adiponectin but barely decreased plasma resistin of ob/ob mice

2004 • 55 citations

The Human apM-1, an Adipocyte-Specific Gene Linked to the Family of TNF's and to Genes Expressed in Activated T Cells, Is Mapped to Chromosome 1q21.3-q23, a Susceptibility Locus Identified for Familial Combined Hyperlipidaemia (FCH)

1999 • 41 citations

Improvement of glucose homeostasis and hepatic insulin resistance in ob/ob mice given oral molybdate

1997 • 40 citations

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1992 • 5 citations