Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

2001 • 4,874 citations

The hormone resistin links obesity to diabetes

2001 • 4,720 citations

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

1995 • 3,159 citations

Cellular mechanisms of insulin resistance

2000 • 2,692 citations

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

2001 • 2,534 citations

AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity

1996 • 2,229 citations

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1992 • 2,216 citations

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

1992 • 2,189 citations

cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)

1996 • 2,082 citations

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

2002 • 2,081 citations

Roles of PPARs in health and disease

2000 • 1,941 citations

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

2001 • 1,903 citations

PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

2001 • 1,659 citations

Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

2000 • 1,438 citations

Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

2001 • 1,285 citations

Adipogenesis and Obesity: Rounding Out the Big Picture

1996 • 1,268 citations

Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation

2002 • 1,132 citations

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy

1999 • 1,040 citations

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

2001 • 896 citations

The role of TNFα and TNF receptors in obesity and insulin resistance

1999 • 771 citations

Genetic Variation in the Gene Encoding Adiponectin Is Associated With an Increased Risk of Type 2 Diabetes in the Japanese Population

2002 • 707 citations

Obesity in the new millennium

2000 • 707 citations

Cellular and Molecular Aspects of Adipose Tissue Development

1992 • 671 citations

Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists

1997 • 614 citations

Molecular Mechanism of Metabolic Syndrome X: Contribution of Adipocytokines · Adipocyte‐derived Bioactive Substances

1999 • 607 citations

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

2000 • 519 citations

Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue.

1992 • 377 citations

Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin.

1999 • 211 citations

The fourth Musketeer ? from Alexandre Dumas to Claude Bernard

1995 • 187 citations

Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice

2002 • 153 citations

Biomechanical Strain Induces Class A Scavenger Receptor Expression in Human Monocyte/Macrophages and THP-1 Cells

2001 • 92 citations

Resistance to Neointimal Hyperplasia and Fatty Streak Formation in Mice With Adrenomedullin Overexpression

2002 • 42 citations