Replication, expression and segregation of plasmid-borne DNA in genetically transformed malaria parasites

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

Transfection of Plasmodium falciparum within human red blood cells.

1995 • 383 citations

Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine.

1996 • 380 citations

Structurally Distinct, Stage-Specific Ribosomes Occur in Plasmodium

1987 • 309 citations

Characterization of promoters and stable transfection by homologous and nonhomologous recombination in Plasmodium falciparum.

1996 • 272 citations

Inducible Gene Expression in Trypanosomes Mediated by a Prokaryotic Repressor

1995 • 248 citations

Stable Transfection of Malaria Parasite Blood Stages

1995 • 239 citations

Nucleosome positioning and modification: chromatin structures that potentiate transcription

1994 • 182 citations

Structure and expression of a post-transcriptionally regulated malaria gene encoding a surface protein from the sexual stages of Plasmodium berghei

1993 • 162 citations

Recombination associated with replication of malarial mitochondrial DNA.

1996 • 160 citations

Recombination associated with replication of malarial mitochondrial DNA.

1996 • 148 citations

Plasmodium berghei: The application of cultivation and purification techniques to molecular studies of malaria parasites

1995 • 142 citations

Microtubular organization visualized by immunofluorescence microscopy during erythrocytic schizogony in Plasmodium falciparum and investigation of post-translational modifications of parasite tubulin

1993 • 115 citations

Transfection of the malaria parasite and expression of firefly luciferase.

1993 • 115 citations

DNA synthesis in Plasmodium berghei during asexual and sexual development

1986 • 110 citations

Synthesis of DNA during the asexual cycle of Plasmodium falciparum in culture

1984 • 103 citations

Expression of a Plasmodium Gene Introduced into Subtelomeric Regions of Plasmodium berghei Chromosomes

1996 • 86 citations

Synchronized erythrocytic schizogony and gametocytogenesis of Plasmodium berghei in vivo and in vitro

1985 • 77 citations

Parasitism and chromosome dynamics in protozoan parasites: is there a connection?

1995 • 77 citations

Plasmodium berghei: Gametocyte production, DNA content, and chromosome-size polymorphisms during asexual multiplication in vivo

1989 • 66 citations

Periodic expression of nuclear and mitochondrial DNA replication genes during the trypanosomatid cell cycle

1994 • 62 citations

Transcriptional differences in polymorphic and conserved domains of a complete cloned P. falciparum chromosome

1993 • 61 citations

Plasmodium species: Flow cytometry and microfluorometry assessments of DNA content and synthesis

1987 • 60 citations

Physical and functional mapping of the transcriptional start sites of Plasmodium falciparum proliferating cell nuclear antigen

1996 • 55 citations

Differential expression in blood stages of the gene coding for the 21-kilodalton surface protein of ookinetes of Plasmodium berghei as detected by RNA in situ hybridisation

1994 • 41 citations

Organelle DNAs: The bit players in malaria parasite DNA replication

1996 • 27 citations

The effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl) adenine on nuclear and organellar DNA synthesis in erythrocytic schizogony in malaria

1994 • 25 citations

Cell cycle regulation of p34 cdc2 kinase activity in Physarum polycephalum

1990 • 23 citations

Strategies for the Genetic Manipulation ofSaccharomyces cerevisiae

1992 • 15 citations