Isolation and sequence analysis of serine protease cDNAs from mouse cytolytic T lymphocytes.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Efficient isolation of genes by using antibody probes.

1983 • 2,065 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

Serine Proteases: Structure and Mechanism of Catalysis

1977 • 1,238 citations

Evolution of Proteolytic Enzymes

1984 • 641 citations

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

Human natural killer cells: biologic and pathologic aspects.

1984 • 419 citations

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1987 • 393 citations

A novel serine esterase expressed by cytotoxic T lymphocytes

1985 • 319 citations

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

1986 • 316 citations

Efficient mapping of protein antigenic determinants.

1986 • 292 citations

Cloning of a cDNA for a T Cell-Specific Serine Protease from a Cytotoxic T Lymphocyte

1986 • 247 citations

Novel Serine Proteases Encoded by Two Cytotoxic T Lymphocyte-Specific Genes

1986 • 246 citations

Serine esterase in cytolytic T lymphocytes

1986 • 240 citations

Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell lines.

1980 • 235 citations

Molecular cloning of human cathepsin G: structural similarity to mast cell and cytotoxic T lymphocyte proteinases

1987 • 218 citations

The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14

1986 • 197 citations

Substrate binding site in bovine chymotrypsin A_γ. Crystallographic study using peptide chloromethyl ketones as site-specific inhibitors

1971 • 181 citations

Isolation and characterization of a serine esterase from cytolytic T cell granules

1986 • 177 citations

The mechanism of cell-mediated cytotoxicity. I. Killing by murine cytotoxic T lymphocytes requires cell surface thiols and activated proteases.

1980 • 155 citations

Granules of cytolytic T-lymphocytes contain two serine esterases.

1986 • 148 citations

Lymphokine-activated killer cells in rats. III. A simple method for the purification of large granular lymphocytes and their rapid expansion and conversion into lymphokine-activated killer cells.

1988 • 147 citations

Covalent structure of a group-specific protease from rat small intestine. Appendix: Crystallographic data for a group specific protease from rat intestine

1978 • 144 citations

Cytotoxic T‐Lymphocytes How Do They Function?

1983 • 124 citations

Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family.

1987 • 122 citations

Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes.

1986 • 112 citations

Cellular and Humoral Mechanisms of Cytotoxicity: Structural and Functional Analogies

1987 • 111 citations

Effects of N alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes.

1980 • 105 citations

Cytotoxic T lymphocyte mediated cytolysis

1988 • 99 citations

Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytes.

1988 • 92 citations

Isolation and initial characterization of multiple species of T-lymphocyte subset cDNA clones.

1987 • 67 citations

cDNA cloning of granzyme C, a granule-associated serine protease of cytolytic T lymphocytes.

1988 • 57 citations

Cell-mediated cytotoxic reactions

1986 • 30 citations

The role of cytoplasmic granule components in cytolutic lymphocyte-mediated cytolysis

1987 • 24 citations

Immune systems: Complement-like cytotoxicity?

1986 • 13 citations