GROWTH FACTORS AND CANCER

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

Epidermal Growth Factor

1979 • 2,964 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1976 • 2,458 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Molecular biology of the cell

1983 • 1,007 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

The cloning of normal “Mast” cells in tissue culture

1965 • 886 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Purification and properties of colony-stimulating factor from mouse lung-conditioned medium.

1977 • 624 citations

Cellular Transforming Genes

1982 • 622 citations

Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor.

1983 • 568 citations

Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus

1980 • 560 citations

An Unidentified Virus which causes the Rapid Production of Tumours in Mice

1964 • 535 citations

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.

1979 • 530 citations

The nature and action of granulocyte-macrophage colony stimulating factors

1980 • 526 citations

Hemopoietic colony-stimulating factors

1984 • 468 citations

In Vitro Experiments on the Effects of Mouse Sarcomas 180 and 37 on the Spinal and Sympathetic Ganglia of the Chick Embryo

1997 • 449 citations

Regulation of B-Cell Growth and Differentiation by Soluble Factors

1983 • 432 citations

Procedures for the purification of interleukin 3 to homogeneity.

1982 • 428 citations

Transforming activity of human tumor DNAs.

1981 • 374 citations

Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.

1984 • 361 citations

Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus

1980 • 356 citations

Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.

1981 • 302 citations

Proteins encoded by v-myc and c-myc oncogenes: Identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines

1983 • 297 citations

Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1)

1981 • 274 citations

Nucleotide Sequence of the p21 Transforming Protein of Harvey Murine Sarcoma Virus

1982 • 272 citations

THE ROLE OF ERYTHROPOIETIN IN REGULATION OF POPULATION SIZE AND CELL CYCLING OF EARLY AND LATE ERYTHROID PRECURSORS IN MOUSE BONE MARROW

1977 • 251 citations

BALB and kirsten murine sarcoma viruses alter growth and differentiation of EGF-dependent BALB/c mouse epidermal keratinocyte lines

1983 • 224 citations

Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors

1980 • 213 citations

The Newer Gut Hormones

1977 • 210 citations

Molecules stimulating early red cell, granulocyte, macrophage, and megakaryocyte precursors in culture: Similarity in size, hydrophobicity, and charge

1982 • 207 citations

Immortalized B lymphocytes produce B-cell growth factor

1984 • 204 citations

Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins

1984 • 203 citations

Detection of epidermal growth factor-urogastrone and its receptor during fetal mouse development

1980 • 186 citations

The regulated expression of β-globin genes introduced into mouse erythroleukemia cells

1983 • 186 citations

Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids

1983 • 182 citations

Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes

1982 • 179 citations

Differential sensitivity of human B cell subsets to activation signals delivered by anti-mu antibody and proliferative signals delivered by a monoclonal B cell growth factor.

1983 • 179 citations

Characterization of a serum factor stimulating the differentiation of myelomonocytic leukemic cells

1980 • 170 citations

chapter 6 Nerve Growth Factors and Control of Nerve Growth

1980 • 158 citations

Hemopoietic Colonies

1977 • 156 citations

A METHOD FOR OBTAINING SUSPENSIONS OF LIVING CELLS FROM THE FIXED TISSUES, AND FOR THE PLATING OUT OF INDIVIDUAL CELLS

1916 • 138 citations

Granulocyte/macrophage-, megakaryocyte-, eosinophil- and erythroid-colony-stimulating factors produced by mouse spleen cells

1980 • 132 citations

Isolation of murine fetal hemopoietic progenitor cells and selective fractionation of various erythroid precursors

1981 • 98 citations

Separable helper factors support B cell proliferation and maturation to Ig secretion.

1982 • 85 citations

Expression of the hepatitis B virus surface, core and E antigen genes by stable rat and mouse cell lines

1982 • 78 citations

Growth Factors and Stem Cells

1984 • 77 citations

The production of committed hemopoietic colony-forming cells from multipotential precursor cells in vitro

1982 • 74 citations

Origin and Function of Avian Retrovirus Transforming Genes

1980 • 70 citations

Simian sarcoma virus, type 1 (Lagothrix): focus assay and demonstration of nontransforming associated virus.

1972 • 67 citations

Susceptibility of suckling-infant, and resistance of adult, mice of the C3h and of the C57 lines to inoculation with AK leukemia

1950 • 47 citations

Characterization of β-globin mRNA in the β0 thalassemias

1978 • 46 citations

Polypeptide growth factors: Some structural and mechanistic considerations

1980 • 42 citations

Gastrin and the transforming protein of polyoma virus have evolved from a common ancestor

1982 • 38 citations

Chapter 11 Early Organization of The Central Nervous System: Form and Pattern

1980 • 21 citations

Readings in mammalian cell culture

1982 • 17 citations

The complex mediators of cell growth and differentiation

1984 • 3 citations