Neuregulin found in cultured-sciatic nerve conditioned medium causes neuronal differentiation of PC12 cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

GDNF: a Potent Survival Factor for Motoneurons Present in Peripheral Nerve and Muscle

1994 • 1,261 citations

Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection.

1987 • 1,012 citations

Identification of Heregulin, a Specific Activator of p185 ^erbB2

1992 • 963 citations

Axons from CNS neurones regenerate into PNS grafts

1980 • 928 citations

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 • 830 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages.

1987 • 711 citations

ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family

1993 • 612 citations

Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons.

1995 • 595 citations

Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons.

1987 • 495 citations

Isoform-specific expression and function of neuregulin

1997 • 384 citations

A diffusible agent of mouse sarcoma, producing hyperplasia of sympathetic ganglia and hyperneurotization of viscera in the chick embryo

1953 • 359 citations

Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor.

1995 • 337 citations

Expression of Neuregulins and their Putative Receptors, ErbB2 and ErbB3, Is Induced during Wallerian Degeneration

1997 • 329 citations

Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve

1989 • 280 citations

Purification of adult rat sciatic nerve ciliary neuronotrophic factor

1986 • 253 citations

Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships.

1993 • 237 citations

Nerve growth activities in rat peripheral nerve

1982 • 235 citations

Neurite-promoting factors and extracellular matrix components accumulating in vivo within nerve regeneration chambers

1984 • 223 citations

Structural and Functional Aspects of the Multiplicity of Neu Differentiation Factors

1994 • 220 citations

Differential effects of NGF, FGF, EGF, cAMP, and dexamethasone on neurite outgrowth and sodium channel expression in PC12 cells

1990 • 181 citations

Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.

1994 • 180 citations

A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation.

1985 • 171 citations

Sensory and Motor Neuron-derived Factor. A NOVEL HEREGULIN VARIANT HIGHLY EXPRESSED IN SENSORY AND MOTOR NEURONS

1995 • 170 citations

Induction of axon growth into schwann cell implants grafted into lesioned adult rat spinal cord

1991 • 168 citations

Rat astrocytes and Schwann cells in culture synthesize nerve growth factor-like neurite-promoting factors

1987 • 165 citations

La influencia del neurotropismo en la regeneracion de los centros nerviosos

1911 • 154 citations

Structural and functional aspects of the multiplicity of Neu differentiation factors.

1994 • 148 citations

Brain neurons and glial cells express Neu differentiation factor/heregulin: a survival factor for astrocytes.

1994 • 147 citations

Regrowth of axons in lesioned adult rat spinal cord: promotion by implants of cultured Schwann cells

1994 • 147 citations

Insulin-like growth factor II stimulates motor nerve regeneration.

1992 • 141 citations

The neuronal cell-surface molecule mitogenic for Schwann cells is a heparin-binding protein.

1988 • 134 citations

Purification and characterization of a trophic factor for embryonic peripheral neurons: Comparison with fibroblast growth factors

1990 • 111 citations

Role of Peripheral Nerve Extracellular Matrix in Schwann Cell Function and in Neurite Regeneration

1989 • 110 citations

Expression of multiple neuregulin transcripts in postnatal rat brains

1994 • 109 citations

Neuronal growth factors produced by adult peripheral nerve after injury

1986 • 89 citations

Schwann Cells Express NDF and SMDF/n-ARIA mRNAs, Secrete Neuregulin, and Show Constitutive Activation of erbB3 Receptors: Evidence for a Neuregulin Autocrine Loop

1997 • 85 citations

Overlapping and Additive Effects of Neurotrophins and CNTF on Cultured Human Spinal Cord Neurons

1994 • 79 citations

Cultured neonatal schwann cells contain and secrete neuregulins

1996 • 74 citations

Peripheral nerve contains heterogeneous growth factors that support sensory neurons in vitro

1981 • 58 citations

Neonatal Oligodendrocytes Contain and Secrete Neuregulins In Vitro

1997 • 54 citations

NGF/BDNF chimeric proteins: analysis of neurotrophin specificity by homolog-scanning mutagenesis

1992 • 50 citations

Schwann cell heparan sulfate proteoglycans play a critical role in glial growth factor/neuregulin signaling

1996 • 41 citations

Neuregulins in glial cells.

1998 • 33 citations

Kinetics of production of a novel growth factor after peripheral nerve injury

1990 • 30 citations

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration

1987 • 28 citations

Diffusible factor(s) from adult rat sciatic nerve increases cell number and neurite outgrowth of cultured embryonic ventral mesencephalic tyrosine hydroxylase‐positive neurons

1990 • 27 citations

Ciliary neurotrophic factor (CNTF) enhances the effects of nerve growth factor on PC12 cells

1994 • 23 citations

Neutrophic influence of denervated sciatic nerve of on adult dorsal root ganglion neurons

1994 • 22 citations

Characterization of a Schwann cell neurite‐promoting activity that directs motoneuron axon outgrowth

1994 • 19 citations

Peripheral nerve extract promotes long-term survival and neurite outgrowth in cultured spinal cord neurons

1984 • 19 citations

Neuronal differentiation of PC12 and chick embryo ganglion cells induced by a sciatic nerve conditioned medium: characterization of the neurotrophic activity

1995 • 18 citations

In situ measurements of external pH and optical density oscillations in Dictyostelium discoideum aggregates.

1986 • 17 citations

Neurotrophic Effects and Mechanism of Insulin, Insulin-Like Growth Factors, and Nerve Growth Factor in Spinal Cord and Peripheral Neurons

1989 • 17 citations

Biological activity of a new neuronal growth factor from injured peripheral nerve

1989 • 16 citations

Influence of factors released from sciatic nerve on adult dorsal root ganglion neurons

1994 • 16 citations

Axotomized frog sciatic nerve releases diffusible neurite-promoting factors

1992 • 11 citations

Multiple neurotrophic factors including NGF-like activity in nerve regeneration chamber fluids

1995 • 10 citations

Neu Differentiation Factor (NDF) and the Neuregulin (NRG) Family

1995 • 2 citations