In Vivo Evidence that 5-HT2C Receptor Antagonist but not Agonist Modulates Cocaine-Induced Dopamine Outflow in the Rat Nucleus Accumbens and Striatum

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors

1985 • 1,855 citations

Neuropsychopharmacology

1990 • 1,545 citations

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors

1985 • 803 citations

SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist

1997 • 519 citations

Neuropsychopharmacology

2003 • 430 citations

Serotonin2C receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and electrophysiological analysis in the rat

2000 • 333 citations

Differential Effects of the 5-HT2A Receptor Antagonist M100,907 and the 5-HT2C Receptor Antagonist SB242,084 on Cocaine-induced Locomotor Activity, Cocaine Self-administration and Cocaine-induced Reinstatement of Responding

2002 • 247 citations

Pattern of expression of the serotonin2C receptor messenger RNA in the basal ganglia of adult rats

1997 • 240 citations

In vitro and in vivo profile of SB 206553, a potent 5‐HT_2C/5‐HT_2B receptor antagonist with anxiolytic‐like properties

1996 • 239 citations

The medical benefit of 5-HT research

2002 • 226 citations

Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study

1999 • 220 citations

5-HT2A and 5-HT2C/2B Receptor Subtypes Modulate Dopamine Release Induced in Vivo by Amphetamine and Morphine in Both the Rat Nucleus Accumbens and Striatum

2002 • 213 citations

Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behavior.

2000 • 209 citations

Enhanced Locomotor, Reinforcing, and Neurochemical Effects of Cocaine in Serotonin 5-Hydroxytryptamine 2C Receptor Mutant Mice

2002 • 152 citations

Opposite change of in vivo dopamine release in the rat nucleus accumbens and striatum that follows electrical stimulation of dorsal raphe nucleus: role of 5-HT3 receptors.

1998 • 143 citations

Evidence for 5-HT4 receptor subtype involvement in the enhancement of striatal dopamine release induced by serotonin: a microdialysis study in the halothane-anesthetized rat

1995 • 136 citations

m-Chlorophenylpiperazine excites non-dopaminergic neurons in the rat substantia nigra and ventral tegmental area by activating serotonin-2C receptors

2001 • 124 citations

Activation of 5-HT2C receptors reduces the locomotor and rewarding effects of nicotine

2001 • 120 citations

The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies.

1990 • 118 citations

DARPP-32 mediates serotonergic neurotransmission in the forebrain

2002 • 116 citations

Use of Calcium Antagonism for the Characterization of Drug-Evoked Dopamine Release from the Brain of Conscious Rats Determined by Microdialysis

1989 • 115 citations

Serotonin 5-HT2C receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine

2002 • 109 citations

Opposite Change ofIn VivoDopamine Release in the Rat Nucleus Accumbens and Striatum That Follows Electrical Stimulation of Dorsal Raphe Nucleus: Role of 5-HT₃Receptors

1998 • 108 citations

Hyperlocomotive and Discriminative Stimulus Effects of Cocaine Are Under the Control of Serotonin_2C(5-HT_2C) Receptors in Rat Prefrontal Cortex

2003 • 104 citations

Pharmacological Studies of the Acute Effects of (+)-3,4-Methylenedioxymethamphetamine on Locomotor Activity, Role of 5-HT1B/1D and 5-HT2 Receptors

2002 • 101 citations

Stimulation of 5‐hydroxytryptamine (5‐HT_2C) receptors in the ventrotegmental area inhibits stress‐induced but not basal dopamine release in the rat prefrontal cortex

2002 • 94 citations

An investigation of the role of 5-HT2C receptors in modifying ethanol self-administration behaviour

2002 • 93 citations

Effects of the 5-HT2C/2B Antagonist SB 206553 on Hyperactivity Induced by Cocaine

1999 • 81 citations

Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1

2002 • 81 citations

Behavioral Effects of 5-HT2CReceptor Antagonism in the Substantia Nigra Zona Reticulata of the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson's Disease

1998 • 80 citations

Activation of mesolimbic dopamine function by phencyclidine is enhanced by 5-HT2C/2B receptor antagonists: neurochemical and behavioural studies

2000 • 75 citations

The effect of serotonergic agents on haloperidol-induced striatal dopamine release in vivo: opposite role of 5-HT2A and 5-HT2C receptor subtypes and significance of the haloperidol dose used

2000 • 74 citations

Serotonin 5-HT2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens

1998 • 74 citations

Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine

1993 • 68 citations

5-HT 3 receptor antagonist MDL 72222 attenuates cocaine- and mazindol-, but not methylphenidate-induced neurochemical and behavioral effects in the rat

2002 • 62 citations

Selective serotonin reuptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens

2003 • 61 citations

Cocaine and central monoaminergic neurotransmission: A review of electrophysiological studies and comparison to amphetamine and antidepressants

1988 • 60 citations

Conditional involvement of striatal serotonin₃ receptors in the control of in vivo dopamine outflow in the rat striatum

2003 • 59 citations

The selective serotonin1A-receptor antagonist WAY 100635 blocks behavioral stimulating effects of cocaine but not ventral striatal dopamine increase

2002 • 49 citations

Central serotonin4 receptors selectively regulate the impulse-dependent exocytosis of dopamine in the rat striatum: in vivo studies with morphine, amphetamine and cocaine

2002 • 48 citations

Systemic and local cocaine increase extracellular serotonin in the nucleus accumbens

1996 • 46 citations

Electrophysiological basis of the reinforcing effects of cocaine

1990 • 46 citations

Serotonin potentiates dopamine inhibition of ventral tegmental area neurons in vitro

1996 • 44 citations

Nigrostriatal Lesions Alter Oral Dyskinesia and c-Fos Expression Induced by the Serotonin Agonist 1-(m-Chlorophenyl)piperazine in Adult Rats

2000 • 43 citations

Effect of acute and chronic administration of the selective 5‐HT_2C receptor antagonist SB‐243213 on midbrain dopamine neurons in the rat: An in vivo extracellular single cell study

2002 • 32 citations

5‐HT_2C receptor antagonists: Potential in schizophrenia

2001 • 23 citations