Modulating Calmodulin Binding Specificity through Computational Protein Design

MOLMOL: A program for display and analysis of macromolecular structures

1996 • 7,169 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

De Novo Protein Design: Fully Automated Sequence Selection

1997 • 1,129 citations

Three-dimensional structure of calmodulin

1985 • 1,035 citations

Target Enzyme Recognition by Calmodulin: 2.4 Å Structure of a Calmodulin-Peptide Complex

1992 • 1,031 citations

How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices

1990 • 839 citations

Molecular and Structural Basis of Target Recognition by Calmodulin

1995 • 752 citations

The dead-end elimination theorem and its use in protein side-chain positioning

1992 • 698 citations

Modulation of Calmodulin Plasticity in Molecular Recognition on the Basis of X-Ray Structures

1993 • 615 citations

Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin

2001 • 586 citations

CALMODULIN AND CALMODULIN-BINDING PROTEINS IN PLANTS

1998 • 467 citations

Tryptophan Fluorescence Quenching by Methionine and Selenomethionine Residues of Calmodulin: Orientation of Peptide and Protein Binding

1998 • 366 citations

Design, structure and stability of a hyperthermophilic protein variant

1998 • 348 citations

Redistribution and loss of side chain entropy upon formation of a calmodulin-peptide complex.

2000 • 298 citations

Efficient rotamer elimination applied to protein side-chains and related spin glasses

1994 • 279 citations

A novel target recognition revealed by calmodulin in complex with Ca2+-calmodulin-dependent kinase kinase.

1999 • 239 citations

On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces

1991 • 213 citations

NMR Solution Structure of a Complex of Calmodulin with a Binding Peptide of the Ca²⁺ Pump^,

1999 • 192 citations

Solution structure of Calmodulin-W-7 complex: the basis of diversity in molecular recognition

1998 • 161 citations

Computational design of an integrin I domain stabilized in the open high affinity conformation.

2000 • 131 citations

Ca²⁺-Binding and Structural Dynamics in the Functions of Calmodulin

1994 • 118 citations

Energetics of Target Peptide Binding by Calmodulin Reveals Different Modes of Binding

2001 • 115 citations

Fluorescence Properties of Calmodulin-Binding Peptides Reflect Alpha-Helical Periodicity

1987 • 112 citations

Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca 2+ /calmodulin-dependent kinase kinase peptide 1 1Edited by K. Morikawa

2001 • 105 citations

Topology of the calmodulin-melittin complex 1 1Edited by P.E. Wright

1998 • 95 citations

Achieving stability and conformational specificity in designed proteins via binary patterning11Edited by C. R. Matthews

2001 • 79 citations

Surface Exposure of the Methionine Side Chains of Calmodulin in Solution

1999 • 78 citations

Methionine to Glutamine Substitutions in the C-terminal Domain of Calmodulin Impair the Activation of Three Protein Kinases

1996 • 76 citations

Computational protein design

2001 • 56 citations

From synthetic coiled coils to functional proteins: automated design of a receptor for the calmodulin-binding domain of calcineurin

1998 • 40 citations

Activation of calcineurin and smooth muscle myosin light chain kinase by Met-to-Leu mutants of calmodulin

1998 • 39 citations

Spectroscopic Characterization of the Interaction between Calmodulin-Dependent Protein Kinase I and Calmodulin

2000 • 32 citations

Thermodynamics of target peptide recognition by calmodulin and a calmodulin analogue: implications for the role of the central linker

1999 • 24 citations

Designing Protein<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi mathvariant="italic">β</mml:mi></mml:math>-Sheet Surfaces by<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi mathvariant="italic">Z</mml:mi></mml:math>-Score Optimization

2000 • 22 citations

Design of a Synthetic Receptor for the Calmodulin-Binding Domain of Calcineurin

1997 • 17 citations