Autonomous Expressions of Cytokine Genes by Human Lung Cancer Cells and Their Paracrine Regulation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Secretory products of macrophages.

1987 • 2,670 citations

Cancer: Principles and Practice of Oncology.

1988 • 1,907 citations

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.

1989 • 753 citations

Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor

1986 • 528 citations

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.

1986 • 396 citations

Macrophages and metastasis--a biological approach to cancer therapy.

1985 • 354 citations

Various human hematopoietic growth factors (interleukin-3, GM-CSF, G- CSF) stimulate clonal growth of nonhematopoietic tumor cells [see comments]

1989 • 294 citations

Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation.

1988 • 247 citations

Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line.

1990 • 241 citations

Human granulocyte-macrophage colony-stimulating factor is a growth factor active on a variety of cell types of nonhemopoietic origin.

1988 • 238 citations

Human glioblastoma cells release interleukin 6 in vivo and in vitro.

1990 • 237 citations

Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.

1992 • 235 citations

Constitutive production of interleukin 6 by ovarian cancer cell lines and by primary ovarian tumor cultures.

1990 • 226 citations

Expression of the interleukin 6 receptor and interleukin 6 in prostate carcinoma cells.

1990 • 154 citations

Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro

1989 • 147 citations

Constitutive production of macrophage colony-stimulating factor by human ovarian and breast cancer cell lines.

1989 • 135 citations

Human granulocyte-macrophagecolony-stimulating factor is a growth factor active on avariety of cell types of nonhemopoietic origin

1988 • 106 citations

Functional and phenotypic analysis of tumor-infiltrating. Lymphocytes isolated from human primary and metastatic. Liver tumors and cultured in recombinant interleukin-2

1989 • 95 citations

Regulation of tumor necrosis factor gene expression in colorectal adenocarcinoma: in vivo analysis by in situ hybridization.

1989 • 90 citations

Expression of major histocompatibility antigens and nature of inflammatory cellular infiltrate in ovarian neoplasms

1983 • 81 citations

IL-4 up-regulates IL-1 receptor antagonist gene expression and its production in human blood monocytes.

1992 • 74 citations

Investigation of cytokine gene expression in human colorectal cancer.

1990 • 71 citations

Macrophage tumor necrosis factor-alpha release is induced by contact with some tumors.

1990 • 70 citations

Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.

1988 • 66 citations

Paraneoplastic syndrome of hypercalcemia and leukocytosis caused by squamous carcinoma cells (T3M-1) producing parathyroid hormone-related protein, interleukin 1 alpha, and granulocyte colony-stimulating factor.

1989 • 58 citations

Granulocyte-macrophage colony-stimulating factor (GM-CSF) production by glioblastoma cells. Despite the presence of inducing signals GM-CSF is not expressed in vivo.

1992 • 57 citations

Role of alveolar macrophages in pulmonary neoplasias

1986 • 54 citations

Constitutive production of granulocyte colony‐stimulating factor and interleukin‐6 by a human lung cancer cell line, KSNY: Gene amplification and increased mRNA stability

1991 • 48 citations

Giant cell carcinomas of the lung producing colony-stimulating factor in vitro and in vivo.

1985 • 45 citations

Production of interleukin 6 from human liver cell lines: production of interleukin 6 is not concurrent with the production of alpha-fetoprotein.

1990 • 45 citations

Stimulation of tumor necrosis factor release from monocytic cells by the A375 human melanoma via granulocyte-macrophage colony-stimulating factor.

1990 • 42 citations

Bladder cancer. Human leukocyte antigen II, interleukin-6, and interleukin-6 receptor expression determined by the polymerase chain reaction

1991 • 32 citations

In situ hybridisation for cytokine gene transcripts in the solid tumour microenvironment

1993 • 30 citations

The immunological network at the site of tumor rejection

1986 • 27 citations

Induction of a 26-kDa membrane-form tumor necrosis factor (TNF)-α in human alveolar macrophages

1993 • 19 citations

Coding region structure of interleukin-8 gene of human lung giant cell carcinoma LU65C cells that produce LUCT/interleukin-8: homogeneity in interleukin-8 genes

1990 • 15 citations

IL-6 in malignant pleural effusions and its augmentation by intrapleural instillation of IL-2

1992 • 14 citations

Colony-stimulating factor (CSF) and CSF-stimulating activity produced by a human giant cell carcinoma of the lung.

1986 • 2 citations