Preproenkephalin mRNA expression in the developing and adult rat brain

Endogenous Opioids: Biology and Function

1984 • 1,223 citations

Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin

1982 • 928 citations

Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides

1982 • 621 citations

Rat brain preproenkephalin mRNA. cDNA cloning, primary structure, and distribution in the central nervous system.

1984 • 540 citations

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

1984 • 486 citations

Localization of preproenkephalin mRNA in the rat brain and spinal cord by in situ hybridization

1987 • 345 citations

Neurotrophic molecules

1989 • 270 citations

Brain Region and Gene Specificity of Neuropeptide Gene Expression in Cultured Astrocytes

1989 • 219 citations

Perinatal development of the endorphin- and enkephalin- containing systems in the rat brain

1979 • 201 citations

Molecular cloning and sequence determination of rat preproenkephalin cDNA: sensitive probe for studying transcriptional changes in rat tissues.

1984 • 190 citations

Biology of Opioid Peptides

1979 • 185 citations

Identification of opioid peptides regulating proliferation of neurons and glia in the developing nervous system

1991 • 163 citations

Expression of preproenkephalin mRNA by cultured astrocytes and neurons.

1988 • 130 citations

Distribution of Enkephalin Immunoreactivity in Germinative Cells of Developing Rat Cerebellum

1985 • 124 citations

A neuropeptide precursor in cerebellum: proenkephalin exists in subpopulations of both neurons and astrocytes.

1990 • 112 citations

Opioid-dependent growth of glial cultures: Suppression of astrocyte DNA synthesis by met-enkephalin

1990 • 108 citations

The regulation of proenkephalin expression in a distinct population of glial cells.

1990 • 107 citations

Endogenous opioids regulate cell proliferation in the retina of developing rat

1991 • 95 citations

Ontogenesis of enkephalinergic systems in rat brain: Post-natal changes in enkephalin levels, receptors and degrading enzyme activities

1980 • 94 citations

Ontogenesis of opiate binding sites and radioimmunoassayable β-endorphin and enkephalin in regions of rat brain

1982 • 90 citations

Cellular localization of proenkephalin mRNA and enkephalin peptide products in cultured astrocytes

1990 • 90 citations

Primary Structure of the Human Proenkephalin Gene

1983 • 73 citations

Cellular localization of proenkephalin mRNA in rat brain: gene expression in the caudate-putamen and cerebellar cortex.

1986 • 69 citations

Quantitation of proenkephalin A messenger RNA in bovine brain, pituitary and adrenal medulla: correlation between mRNA and peptide levels.

1985 • 68 citations

In Situ Hybridization: A Methodological Guide

1989 • 61 citations

Prenatal ontogeny of neurons with enkephalin-like immunoreactivity in the rat central nervous system: an immunohistochemical mapping investigation.

1982 • 43 citations

Heterogeneous expression of car☐ypeptidase E and proenkephalin mRNAs by cultured astrocytes

1992 • 42 citations

Ontogeny of zeta (ζ), the opioid growth factor receptor, in the rat brain

1992 • 37 citations

Developmental expression of the proenkephalin and prosomatostatin genes in cultured cortical and cerebellar astrocytes

1992 • 37 citations

Developmental expression of proenkephalin mRNA and peptides in rat striatum

1989 • 34 citations

Ultrastructural localization of enkephalin-like immunoreactivity in developing rat cerebellum

1990 • 33 citations

Postnatal expression of opioid genes in rat brain

1989 • 33 citations

Growth factors, their receptors and development

1989 • 33 citations

Differential regulation of proenkephalin expression in astrocytes by cytokines.

1992 • 28 citations

Transient increases and individual variations in preprocholecystokinin gene expression in rat telencephalic regions during postnatal development: a quantitative comparison between preprocholecystokinin mRNA and preproenkephalin mRNA

1988 • 26 citations

The abnormal cerebellar organization of weaver and reeler mice does not affect the cellular distribution of three neuronal mRNAs

1988 • 25 citations

Detection of the mRNA coding for enkephalin precursor in the rat brain and adrenal by using an ‘in situ’ hybridization procedure

1986 • 25 citations

Differential ontogenetic expression and regulation of proenkephalin and preprosomatostatin mRNAs in rat caudate-putamen as studied by in situ hybridization histochemistry

1991 • 25 citations

Tissue- and treatment-specific usage of multiple preproenkephalin transcriptional start sites.

1992 • 23 citations

Postnatal development of preproenkephalin mRNA containing neurons in the rat lower brainstem

1990 • 22 citations

Differential regulation of proenkephalin expression in astrocytes by cytokines

1992 • 19 citations

Localization of preproenkephalin a mRNA in the neonatal rat retina

1991 • 19 citations

Interleukin‐1β regulates proenkephalin gene expression in astrocytes cultured from rat cortex

1992 • 17 citations

Regulation of adrenomedullary preproenkephalin mRNA: effects of hypoglycemia during development

1992 • 16 citations

Expression of proenkephalin mRNA in developing cerebellar cortex of the rat: expression levels coincide with maturational gradients in Purkinje cells

1991 • 16 citations

Expression of vasopressin and opiates but not of oxytocin genes studied by in situ hybridization in embryonic rat brain primary cultures

1990 • 14 citations

Ontogeny of proenkephalin gene expression in the rat hypothalamus

1991 • 14 citations

Perinatal morphine exposure alters peptidergic development in the striatum

1992 • 11 citations

In Situ mRNA Hybridization: Standard Procedures and Novel Approaches

1989 • 7 citations